95 results about "Biological immunity" patented technology

The present invention relates to compositions and methods for treatment of microbial disorder by modulation of the host immune response. More particularly, the present invention relates to compositions that mediate an anti-microbial immune response, and methods of treating a microbial infection using such compositions.

The invention relates to a dipterex bionic enzyme linked immunosorbent detection method. The bionic enzyme linked immunosorbent detection method with high sensitivity on the dipterex is established by using a dipterex molecular imprinting polymer film as an artificial antibody instead of a biological antibody and by utilizing an enzyme linked immunosorbent assay principle. The lowest detection limit of the method is 7 ugL<-1> and is far less than the highest residue limit value; and the analysis time is greatly shortened (by 1.0 hour compared with the traditional biological immune analysis time), so the method is applicable to rapid detection of the dipterex. A bionic antibody prepared by the method can be reused for more than 50 times, so cost is greatly reduced; and the method is simplein pretreatment, high in sensitivity, simple in test operation and applicable to rapid detection of the dipterex in various kinds of food.

The invention relates to an oestrone derivative for detecting oestrone content in a biological sample and a preparation method of the oestrone derivative. The structural formula of the oestrone derivative is shown as a formula (I). Oestrone immunogens with high immunogenicity and corresponding antibodies are prepared in succession by using the oestrone derivative. The oestrone immunogen is high inspecificity and high in immunogenicity, and the anti-oestrone specific antibody is high in specificity and high in titer, is capable of well recognizing and binding oestrone, and does not have any cross reaction with common 92 chaff interferents. The invention further discloses an oestrone enzyme-labeled conjugate, and an oestrone homogeneous enzyme immunoassay detection reagent is prepared by utilizing the anti-oestrone specific antibody and the oestrone enzyme-labeled conjugate. The reagent is capable of conveniently, rapidly, and accurately measuring the oestrone content in the biologicalsample, multiple samples are determined on a full-automatic biochemical analyzer, high throughput and rapid determination of the oestrone is realized, the accuracy is high, the specificity is high, and the accuracy and detection efficiency are greatly improved compared with the previous detection.

The invention belongs to the field of immunobiology and relates to immunogenic polypeptide of 71-type VP1 antigen of enterovirus, a preparation method and application thereof, and particularly relatesto the immunogenic polypeptide of the 71-type VP1 antigen of the enterovirus. The immunogenic polypeptide has an amino acid sequence shown as any sequence of SEQ ID NO.1-SEQ ID NO.5 in a sequence table, or an amino acid sequence formed by substituting, deleting or adding one or more amino acids for the sequence and with equal functions. The invention also relates to the preparation method of theimmunogenic polypeptide and the application to preparation of a diagnostic reagent for EV71 viruses. The immunogenic polypeptide has good antigenicity and immunogenicity and provides research basis for early development of the diagnostic reagent and vaccine research and development of EV71.

The invention discloses a preparation method of a bioimmune sensor with dual signal development strategies of electrochemiluminescence and photoelectrochemistry constructed on the basis of functional nanomaterials. The prepared sensor is simple to operate, easy to carry, fast to detect, and low in cost, and can be used in Rapid and sensitive detection of ethinyl estradiol in daily production, life and other fields.