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Antimony halide medicine composition for treating leukemia and lymphoma

A technology of antimony halides and compositions, which is applied in the field of pharmaceutical compositions for the treatment of leukemia and malignant lymphoma, and can solve problems such as limited curative effect

Inactive Publication Date: 2004-07-28
苏州市第二人民医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] Cancer is a disease that seriously endangers human health. The current treatment methods are mainly surgery, radiotherapy, and chemotherapy, but all of them have limited efficacy.

Method used

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  • Antimony halide medicine composition for treating leukemia and lymphoma
  • Antimony halide medicine composition for treating leukemia and lymphoma
  • Antimony halide medicine composition for treating leukemia and lymphoma

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0081] Embodiment one: a kind of antimony halide pharmaceutical composition for the treatment of leukemia and lymphoma, containing antimony trichloride (SbCl 3 ), its content is 10mg / m 2 d. The rest are pharmaceutical carriers and / or excipients.

Embodiment 2

[0082] Embodiment two: a kind of antimony halide pharmaceutical composition for the treatment of leukemia and lymphoma, containing antimony trichloride (SbCl 3 ) and cytarabine, antimony trichloride (SbCl 3 ) content is 8mg / m 2 d, the content of cytarabine is 50mg / m 2 d. The rest are pharmaceutical carriers and / or excipients.

Embodiment 3

[0083] Embodiment three: a kind of antimony halide pharmaceutical composition for the treatment of leukemia and lymphoma, containing antimony trichloride (SbCl 3 ) and vincristine, antimony trichloride (SbCl 3 ) content is 5mg / m 2 d, the content of vincristine is 2mg / m 2 d. The rest are pharmaceutical carriers and / or excipients.

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PUM

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Abstract

The invented compound contains effective dose of antimony halide and medicinal carrier and / or excipient. The described antimony halide includes antimonous chloride, antimonous bromide, antimonous triiodide, antimonous fluoride, antimonous pentafluoride and antimony pentachloride, the active component in the described compound is one of the above-mentioned antimony halide or their combination. Said invention relates to adoption of antimony halide, special SbCl3 to cure various leukemia and malignant lymphoma.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating malignant tumors, in particular to a pharmaceutical composition for treating malignant tumors with at least antimony halide as an active ingredient, preferably treating leukemia and malignant lymphoma. Background technique [0002] 1. Introduction to Leukemia and Malignant Lymphoma [0003] Leukemia refers to malignant tumors of blood-forming tissues. In a single cell, transformation to malignancy typically occurs in two or more steps, followed by proliferation and clonal expansion. In some leukemias, specific chromosomal translocations have been identified with consistent leukemic cell morphology and specific clinical features (eg, in chronic myeloid leukemia, translocations of chromosomes 9 and 22; in acute promyelocytic Translocations of chromosomes 15 and 17 in leukemia). Acute leukemia is mainly dominated by undifferentiated cell populations, and chroni...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K33/24A61P35/00A61P35/02
Inventor 何志洁
Owner 苏州市第二人民医院
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