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Medicine contg. bamboo viegar, chitosan and silver ion, and prepn. method and application thereof

A technology of chitosan and silver ions, applied in botany equipment and methods, medical preparations containing active ingredients, applications, etc., can solve the problems of short validity period, failure, and the curative effect is only half a year.

Inactive Publication Date: 2006-09-06
翁莹冰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Although relevant medical and scientific research workers have done a lot of research and developed many medicines for treating and preventing skin diseases such as beriberi: everything from insoles, socks to external washing potions, these methods and medicines have a short period of validity, and most of them can be cured within half a day. It will recur within a month, and the curative effect is only half a year.
In addition, tinea manuum, psoriasis, jock itch, tinea versicolor and other scabies skin diseases as well as pruritus, acne, body odor, etc. are all common skin diseases, and there are many factors that affect the therapeutic effect of external medicines for skin diseases. Rapidly absorbed by the epidermal tissue of the skin, unstable medicinal ingredients, volatile and ineffective, short duration of medicinal efficacy, and prone to drug resistance are the main reasons for the low cure rate of skin diseases
At present, there is still a lack of externally used drugs for skin diseases such as beriberi with strong antibacterial power, long-lasting antibacterial effect, no drug resistance, no allergies to the skin, and no irritation.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0018] The preparation method of the medicament of the present invention is to control the acetic acid content in the bamboo vinegar at 3%-6%, filter the bamboo vinegar to remove impurities and sediments, and then make the powdery or flake deacetylation degree 75%-85%. Chitosan with a viscosity of 0.30-0.50 Pa·S and a molecular weight of less than 100,000 is added to the bamboo vinegar according to the formula ratio, and the addition amount is 0.5%-3.0% of the bamboo vinegar. Constantly stir until the chitosan dissolves completely, and control the pH value in the range of 2.0-2.5. The solution is filtered to remove insoluble matter, and the chitosan solution is allowed to stand to be a uniform glue, and then the silver nitrate solution is added, and the silver ion addition ( (calculated as silver-Ag) is 0.05%-0.1% and stirred for about 30 minutes, allowing the silver ion to fully complex with chitosan to form a silver ion coordination compound.

[0019] In the above-mentioned ...

Embodiment 1

[0023] In this example, the bamboo vinegar is adjusted to contain 3%-4% acetic acid, and the impurities and precipitates are removed by filtration, and then the degree of deacetylation in powder or flake form is 75%-85%, the viscosity is 0.30-0.50Pa·S, and the molecular weight is < 100,000 chitosan is added in the bamboo vinegar liquid according to the formula ratio, and the addition amount is 1.0% of the bamboo vinegar. Stir continuously until the chitosan is completely dissolved, and control the pH value in the range of 2.0-2.5. Solution filtration, remove insoluble matter, leave standstill overnight, allow chitosan solution to be uniform chitosan derivative glue, then add silver nitrate solution, silver ion addition (in terms of Ag) is 0.05%, and stir about For 30 minutes, allow the silver ion to fully complex with the chitosan derivative to form a silver ion coordination compound. The process of this example is suitable for producing the spray agent of the present inventi...

Embodiment 2

[0025] In this embodiment, the bamboo vinegar is adjusted to contain 4%-5% acetic acid, and the impurities and precipitates are removed by filtration, and then the powdery or sheet-like deacetylation degree is 75%-85%, the viscosity is 0.30-0.50Pa·S, and the molecular weight is < 100,000 chitosan is added in the bamboo vinegar liquid according to the formula ratio, and the addition amount is 1.5% of the bamboo vinegar. Stir continuously until the chitosan is completely dissolved, and control the pH value in the range of 2.0-2.5. The solution is filtered to remove insolubles, left standing overnight, allowing the chitosan solution to be a uniform chitosan derivative glue, then adding the silver nitrate solution, the silver ion addition (in Ag) is 0.1%, and stirring for about 30 Minutes, let the silver ion fully complex with the chitosan derivative to form a silver ion coordination compound. The process of this embodiment is suitable for manufacturing the medicament for spreadi...

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Abstract

A medicine containing bamboo vinegar, chitosan and silver ions for treating dermatopathy, such as beriberi, is prepared through filtering bamboo, vigegar, adding the deacetylated chitosan, stirring for full dissolving, regulating pH=2.0-2.5, filtering, laying aside, adding the solution of silver nitrate, and stirring for 30 min. Its advantages are broad spectrum, high and durable curative effect, and high safety.

Description

technical field [0001] The invention relates to a medicament containing bamboo vinegar, chitosan and silver ions, a preparation method and application thereof. Background technique [0002] Although relevant medical and scientific research workers have done a lot of research and developed many medicines for treating and preventing skin diseases such as beriberi: everything from insoles, socks to external washing potions, these methods and medicines have a short period of validity, and most of them can be cured within half a day. It will relapse again within a month, and the curative effect is only half a year. In addition, tinea manuum, psoriasis, jock itch, tinea versicolor and other scabies skin diseases as well as pruritus, acne, body odor, etc. are all common skin diseases, and there are many factors that affect the therapeutic effect of external medicines for skin diseases. Rapidly absorbed by the epidermal tissue of the skin, unstable medicinal ingredients, volatile a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01N65/00A61K31/716A61K33/38A61P17/00A01N65/44
Inventor 翁莹冰翁仁发
Owner 翁莹冰
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