Medicine for acute ischemic apoplexy and its preparing method
A technology for ischemic stroke and acute phase, which is applied in drug combinations, pharmaceutical formulations, medical preparations containing active ingredients, etc. The effect of reducing the size of infarct in the brain and improving the physical syndrome of hemiplegia
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Embodiment 1
[0017] 1. Take 200g of Danshen decoction pieces, add 10 times the amount of water, heat and decoct 3 times, 1.5 hours each time, combine 3 times of water extracts, concentrate under reduced pressure to a relative density of 1.10-1.15 (50°C), add 5% gelatin Aqueous solution, stirring continuously, until the supernatant does not produce precipitation, let it stand for 30 minutes, add ethanol until the alcohol content reaches 75%, stir evenly, refrigerate for 24 hours, filter, recover ethanol under reduced pressure and concentrate to a relative density of 1.30 ( 60°C), vacuum-dried to obtain Danshen extract.
[0018] 2. Take 180g of Radix Paeoniae Rubra, crush it into a coarse powder, add 6 times the amount of 70% ethanol, heat and reflux twice, each time for 2 hours, combine the two alcohol extracts, recover the ethanol under reduced pressure and concentrate to a relative density of 1.10-1.15 (50°C), refrigerated for 72 hours, filtered, the filtrate was extracted 4 times with an...
Embodiment 2
[0022] 1. Take 220g of Danshen decoction pieces, add 13 times the amount of water, heat and decoct twice for 2.5 hours each time, combine the two water extracts, concentrate under reduced pressure to a relative density of 1.10-1.15 (50°C), add 5% gelatin Aqueous solution, stirring continuously, until the supernatant does not produce precipitation, stand still for 60 minutes, add ethanol until the alcohol content reaches 80%, stir evenly, refrigerate for 48 hours, filter, recover ethanol under reduced pressure and concentrate to a relative density of 1.35 ( 60°C), vacuum-dried to obtain Danshen extract.
[0023] 2. Take 200g of Radix Paeoniae Rubra, crush it into a coarse powder, add 8 times the amount of 80% ethanol, heat and reflux 3 times, each time for 2 hours, combine the ethanol extract, recover the ethanol under reduced pressure and concentrate to a relative density of 1.10-1.15 (50 ℃), refrigerated for 28 hours, filtered, and the filtrate was extracted 5 times with an e...
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