Combination of medication for treating obstetrical diseases and preparation method

A technology for obstetric diseases and compositions, which is applied in the direction of drug combination, pharmaceutical formula, drug delivery, etc., can solve the problems of unsatisfactory extraction of active ingredients, difficult quality, large solvent and time consumption, and achieve the effect of easy product quality standards

Inactive Publication Date: 2005-08-31
WUHAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, most traditional Chinese medicines for postpartum qi deficiency and blood stasis need to be decocted, which consumes a lot of solvents and time, and the extraction of active ingredients is not satisfactory.
Such as traditional biochemical soup, the quality is difficult to control uniformly, it is inconvenient to carry and store, it is not easy to industrial production and other factors affect its wide application

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] 120 parts of angelica, 95 parts of Chuanxiong, 30 parts of peach kernel

[0055] 10 parts of roasted licorice, 10 parts of ginger

[0056] Its preparation steps are as follows:

[0057] ①Put the Chinese herbal decoction pieces of angelica, chuanxiong, peach kernel, paojiang, and licorice in a pulverizer to pulverize, and then pass through a 100-mesh sieve, and mix the powders of different medicinal materials after pulverization, put them in an extraction tank, and add ethanol Aqueous solution, and introduce microwave extraction to make it move at a speed of 2.5 billion times / second. Extract.

[0058] ②Put the above extract in a vacuum decompression concentration tank for decompression concentration at a temperature of 30°C or 50°C for 4 or 10 or 20 or 30 or 40 or 60 or 72 hours, and at the same time collect volatile substance;

[0059] ③Combine the decompression concentrate and volatile substances into the spray drying tower, use supersonic jet technology, the jet v...

Embodiment 2

[0062] Angelica 90 parts, Chuanxiong 120 parts, peach kernel 40 parts

[0063] 15 parts of roasted licorice, 15 parts of gunjiang

[0064] Its preparation step is identical with 1.-3. in embodiment 1, and the 4th step is according to Chinese Pharmacopoeia 2000 edition two preparation microcapsule standards, does not add adjuvant material, makes nanometer compound traditional Chinese medicine microcapsule, each consumption is 1-2g, Take 1-4 times a day.

Embodiment 3

[0066] Angelica 100 parts, Chuanxiong 110 parts, peach kernel 50 parts

[0067] 20 parts of roasted licorice, 20 parts of gunjiang

[0068] Its preparation steps are identical with 1.-3. in embodiment 1, and the 4. step is according to Chinese Pharmacopoeia 2000 edition two preparation film standard, film-forming material adopts polyvinyl alcohol, makes nano biochemical film agent, and the size of every film area is 2 -100 square centimeters, the drug content is 1-50 grams, each film is applied for 1-7 days, and the application sites: abdomen, back, chest.

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PUM

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Abstract

A Chinese medicine for treating obstetrical diseases is prepared from 5 Chinese-medicinal materials including Chinese angelica root, Chuan-xiong rhizome, peach kernel, liquorice root, etc through slicing, pulverizing, proportionally mixing, preparing nanoparticles, microwave extracting, vacuum concentrating, and spray drying.

Description

technical field [0001] The invention belongs to the field of treating obstetric diseases of promoting blood circulation, removing blood stasis, warming meridians and relieving pain, and more specifically relates to a pharmaceutical composition for treating obstetric diseases, and also relates to a preparation method of the medicine. Background technique [0002] This medicine is derived from a classic obstetric prescription, and it is mainly used for postpartum blood stasis and lochia. Clinically, it mainly treats postpartum diseases and some gynecological diseases. The former includes uterine involution incompleteness, postpartum lochia, induced abortion, vaginal bleeding after medical abortion, postpartum fever, endometritis, placental membrane residue, postpartum abdominal pain, etc., and the latter Including uterine fibroids, uterine hypertrophy and metrorrhagia. [0003] At present, most traditional Chinese medicines for treating postpartum ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/00A61P15/00
Inventor 宋金春杨芰王芳杨鹤曾俊芬徐明霞彭燕
Owner WUHAN UNIV
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