Preparation of Chinese medicine clinopodium polycephalum saponin

A technology of cutting off blood flow and total saponins, which is applied to the preparation process of effective parts of traditional Chinese medicine and its pharmaceutical application field, and can solve problems such as large dosage, unstable quality, and unclear quality control indicators

Inactive Publication Date: 2005-10-12
李也实
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, there are gynecological hemostatic drugs such as Duanxue Flow Tablets currently available in the market: ①Water-extracted and alcohol-precipitated or alcohol-extracted water-precipitated cru

Method used

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Examples

Experimental program
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Embodiment Construction

[0081] Described preparation method:

[0082] way one

[0083] (1) Extraction section

[0084] Take blood-breaking medicinal materials that meet the requirements of the current edition of "Chinese Pharmacopoeia", cleanly select, remove weeds and roots, cut into 2-3 cm sections, and put 100 kg (total saponin content 0.31%) into a multifunctional extraction tank, Add 12 times the amount of neutral water (pH value 6.5 to 7.5), soak for 24 hours, extract for 1 hour, filter (pass through a 200-mesh sieve), and centrifuge; add 12 times the amount of neutral water to extract the drug residue 3 times, each time 1 hour, filter, combine, operate as above, pour the extract into a concentration tank, concentrate under reduced pressure to a concentrated solution with a relative density of 1.10-1.15 (thermal measurement at 60°C), cool to room temperature, add ethanol to the alcohol content 50% to 60%, stir evenly, stand for 24 to 48 hours, filter, and recover ethanol from the filtrate; wa...

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PUM

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Abstract

Production of Chinese medicine Duanxueliu total saponin is carried out by extracting, enriching, refining and obtaining Duanxueliu total saponin. It is effective part of Duanxueliu , total saponin is >=50%, Duanxueliu saponin A is >=5%. It can be used for medicaments research, tablet, chewing tablet, capsule, soft capsule, oral liquid, syrup, dropping pill and injection.

Description

technical field [0001] The invention belongs to a preparation process of an effective part of a traditional Chinese medicine and its medicinal application, in particular to a preparation process of the effective part of the traditional Chinese medicine for treating hemorrhage, especially gynecological hemorrhagic diseases - total saponins of blood-breaking and its medicinal application. Background technique [0002] Bleeding diseases are very common in daily life and clinical practice, especially gynecological hemorrhage, such as: functional uterine bleeding, menorrhagia, metrorrhagia, various gynecological bleeding caused by family planning measures, etc. 1 / 3. Gynecological bleeding is related to various factors such as hormones and endocrine functions in the body. The use of chemical drugs to stop bleeding can only cure the symptoms, and the effect is not ideal. However, the types of chemical drugs used for the treatment of bleeding diseases are limited, and they also have...

Claims

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Application Information

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IPC IPC(8): A61K9/00A61P7/04A61P15/00C07H1/08
Inventor 李也实
Owner 李也实
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