Hysteromyoma treating suppository and its preparing method

Abstract

The present invention discloses a kind of hysteromyoma treating suppository and its preparation process. The hysteromyoma treating suppository is prepared with danozol 10-20 wt%, stearic acid 10-20 wt% and semi-synthetic fatty acid ester 60-80 wt%. The preparation process includes the following steps: heating stearic acid and semi-synthetic fatty acid ester in water bath at 60-90 deg.c; adding danozol after cooling to 40-50 deg.c; preparing in hot smelting process and sealing and packing. The present invention has the beneficial effects of: raised curative effect, reduced toxic side effect on liver of the medicine, less stimulation on stomach, etc.

Description

technical field [0001] The invention relates to a suppository for treating uterine fibroids and a preparation method thereof. Background technique [0002] Uterine fibroids (myoma of uterus) is the most common benign tumor in female reproductive organs, more common in women aged 30-50, it is estimated that about 20%-25% of women aged 35-50 suffer from uterine fibroids [1] . 335 Swiss women aged 25-40 were randomly selected, and the incidence rate of uterine fibroids was 5.4% in vaginal B-ultrasound examination. The prevalence of fibroids increases with age, 7.8% for 33-40 years old. The incidence of autopsy fibroids is 50%. Among the 10 uterine specimens undergoing hysterectomy for other reasons, the incidence of fibroids was found to be 77% in serial sections at intervals of 2 mm. Black women are three times more likely to have fibroids than white women, based on ultrasound and hysterectomy specimens. Fibroids occur in 6%-34% of women undergoing hysteroscopy for vagina...

AI Technical Summary

Problems solved by technology

[0011] ①The drug has great toxic and side effects on the liver;

[0012] ②The drug has great irritation to the stomach;

[0013] ③ Drugs are easily destroyed by digestive juices;

[0014] ④Slow absorption, slow onset, long acting time