Technique for preparing embolism agent of granule of polyvinyl alcohol

Abstract

A process for preparing the granular embolizing agent from polyvinyl alcohol includes such steps as dissolving polyvinyl formal in aseptic water for injection, freezing at -20--40 deg.C for 10-12 hr, planning on the obtained ice block multiple times to obtain ice particles, classifying by wet sieving by immersing the sieve in suspension to obtain wet polyvinyl formal particles, freezing again, and dry sieving for classifying.

Description

technical field [0001] The invention relates to a preparation process of an embolic agent, in particular to a preparation process of a polyvinyl alcohol particle embolic agent. Background technique [0002] Currently in medical technology, as interventional therapy becomes more mature, it is used more and more frequently. The key technology of interventional therapy is that the granular embolic agent used to block the blood supply of tumor tissue has high requirements on the size of the particles, and the foam particles are now imported from abroad, which are more expensive; The manufacturing process is the problem to be solved by the present invention. [0003] The pulverization of materials mainly uses external mechanical force, impact, crushing and grinding to destroy the cohesion between the molecules of the material, so as to achieve the purpose of pulverization. The most effective pulverizing technologies and machines at present are: (1) Impact pulverizing technology...

AI Technical Summary

Problems solved by technology

[0005] The deficiency of the method of the present invention is: due to drying immediately after freezing and crushing, and then sieving, the large and small particles are mixed together, and due to the electrostatic adsorption of the particles, the large and small particles are aggregated, and it is difficult to disperse them