Use of -(4-hydroxy-3-methoxyphenyl)-7-(4- hydroxyphenyl)-3,5-dihydroxy heptane
A technology of methoxyphenyl and hydroxyheptane is applied in the field of extracting diarylheptane compounds from galangal, and can solve the problems such as no public reports on anti-Candida albicans.
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Embodiment 1
[0009] A method for extracting diaryl heptane compound 1-(4-hydroxyl-3-methoxyphenyl)-7-(4-hydroxyphenyl)-3,5-dihydroxyheptane from Galanga, comprising Follow the steps below:
[0010] (1) 3.5 kilograms of galangal medicinal materials are pulverized, (galangal was purchased from Tianjin Chinese Herbal Pieces Factory in March, 2004, identified by the Pharmacy Teaching and Research Office of Tianjin Medical University) plus 10 kilograms of ethanol aqueous solution with a concentration of 90% by volume, heated to reflux for 6 After 1 hour, the extract was filtered, extracted 3 times, and the filtrate was concentrated under reduced pressure to 50°C when the relative density was 1.10 extract (300g), added distilled water 4 times the mass of the extract to dissolve, extracted 3 times with chloroform, The extract was concentrated under reduced pressure to obtain 150 g of chloroform extract. The extract was separated by silica gel column chromatography (1.2 kg, 100-200 mesh), and pet...
Embodiment 2
[0015] Antibacterial activity of 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-3,5-dihydroxyheptane
[0016] compound
Embodiment 3
[0018] Combining 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-3,5-dihydroxyheptane with pharmaceutically acceptable carriers to make various dosage forms, For the treatment of diseases caused by Candida albicans.
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