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Method for capturing ion in Multipole ion trap and multipole ion trap device

An ion trap, ion trap technology, applied in the direction of positive/negative analyte ion analysis/introduction/generation, particle separation tube, discharge tube, etc., to achieve the effect of high signal-to-noise ratio

Active Publication Date: 2010-12-29
THERMO FINNIGAN
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, conventional multipole trapping can only simultaneously confine particles whose mass / charge ratios do not differ by more than a factor of a few hundred

Method used

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  • Method for capturing ion in Multipole ion trap and multipole ion trap device
  • Method for capturing ion in Multipole ion trap and multipole ion trap device
  • Method for capturing ion in Multipole ion trap and multipole ion trap device

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Embodiment Construction

[0024] figure 1 Shown is a mass spectrometry system 100 operating in accordance with one aspect of the present invention. System 100 includes a precursor ion donor 110 , a 2D multipole ion trap 120 , a reagent ion donor 130 and a controller 140 . The precursor ion donor 110 is used to generate ions, which include precursor ions. Ions generated by precursor ion donor 110 are implanted into 2D multipole ion trap 120 . The reagent ion donor 130 generates ions including reagent ions. Ions generated by the reagent ion donor 130 are also injected into the 2D multipole ion trap 120 . The 2D multipolar ion trap 120 forms a channel, wherein the oscillating potential generated by the periodically varying voltage applied to the different electrodes in the ion trap 120 by the controller 140 from the precursor ions and the reagent ions is confined in the radial direction and the axial direction. in this channel.

[0025] Precursor ion donor 110 includes: one or more precursor ion sour...

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Abstract

Methods and apparatus for trapping or guiding ions. Ions are introduced into an ion trap or ion guide. The ion trap or ion guide includes a first set of electrodes and a second set of electrodes. The first and second sets of electrodes are arranged to define an ion channel to trap or guide the introduced ions. Periodic voltages are applied to electrodes in the first set of electrodes to generate a first oscillating electric potential that radially confines the ions in the ion channel, and periodic voltages are applied to electrodes in the second set of electrodes to generate a second oscillating electric potential that axially confines the ions in the ion channel.

Description

[0001] Cross References to Related Applications [0002] This application claims priority to U.S. copending patent application Ser. No. 10 / 764,435, filed January 23, 2004, entitled "Confining Positive and Negative Ions with Fast Oscillation Electric Potentials," which is hereby incorporated by reference in its entirety. technical field [0003] The present invention relates to mass spectrometers. Background technique [0004] A mass spectrometer analyzes the mass of sample particles, such as atoms, molecules, etc., and typically includes an ion source, one or more mass analyzers, and one or more detectors. In the ion source, sample particles are ionized. Sample particles can be ionized using a variety of techniques, such as chemical reactions, electrostatic forces, laser beams, electron beams, or other particle beams. The ions are transmitted to one or more mass analyzers so that they separate the particles based on their mass / charge ratio. This separation can be in time,...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): H01J49/42
CPCH01J49/063H01J49/0095H01J49/4225H01J49/0072
Inventor 约翰·E·P·西卡
Owner THERMO FINNIGAN
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