Method for preparing hollow fiber with temperature sensitive medicinal hydrogel and application thereof

Abstract

The invention relates to a method for preparing temperature-sensitive aquagel hollow fiber, wherein it uses hollow fiber as carrier, whose chamber contains temperature-sensitive aquagel; the aquagel will change phase at human temperature to release the drug. And the preparation comprises a, holding the holes of hollow fiber; b, putting temperature-sensitive monomer solution into the chamber of hollow fiber; c, compositing temperature-sensitive aquagel in the chamber; d, using said aquagel to absorb drub. The invention has better temperature-sensitive property and slow-release property.

Description

technical field

[0001] The invention relates to a preparation method and application of a thermosensitive drug carrier hollow fiber, in particular to a drug temperature-sensitive hydrogel hollow fiber capable of realizing drug temperature-sensitive release, and a preparation method and application thereof. Background technique

[0002] The treatment of various acute and chronic diseases can be realized through the release of drugs. At present, various release systems such as tablets, injections, suppositories, ointments, and aerosols have been formed. However, due to various reasons, using these common drug administration methods, the drug concentration in the human body can only be maintained for a short period of time and fluctuates greatly; Inconvenient, often difficult to be accepted by patients. Therefore, the traditional drug release system cannot fully meet the needs of patients, and new controllable drug release systems have received more and more attention. [000...

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