Slow released capsule of lindamycin sodium and bletilla tuber glue for animal and birds
A linomycin sodium, bioadhesion technology, applied in the direction of drug delivery, plant raw materials, medical preparations with inactive ingredients, etc., can solve the problem of unsatisfactory adhesion and drug release performance, dangerous disease threats, safety Not ideal and other problems, to achieve the effect of improving drug treatment effect, good treatment effect, and improving bioavailability
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Embodiment 1
[0013] Example 1: Preparation of Linmycin Sodium Bletilla Gum Bioadhesive Sustained Release Capsules
[0014] a. Preparation of Bletilla striata gum: Bletilla striata 5kg, crushed, added 40L of distilled water, heated in a water bath at 60°C, soaked and stirred, the extract is filtered through four layers of gauze, and the medicine residue is added with distilled water, repeated dipping, combining the filtrate several times, and concentrating, Add 95% ethanol to make the alcohol content reach 70%, and a large amount of white flocculent precipitate will be deposited. Let it stand overnight, filter the next day, recover the ethanol, collect the precipitate, wash with ethanol 3 times, evaporate the ethanol, and dry at about 80°C , Weighing, smashing, you can get 1.1kg of Bletilla striata gum; Bletilla striata gum: It is yellow dry powder, tasteless and odorless, insoluble in ethanol, soluble in water, and a thick colloid. α-Naphthol concentrated sulfuric acid and alkaline copper tart...
Embodiment 2
[0016] Example 2: The prepared Linmycin sodium and Bletilla gum bioadhesive sustained-release capsules are used to treat livestock and poultry infections caused by Staphylococcus, Streptococcus pneumoniae, Escherichia coli, and typhoid bacilli. The mode of administration is mixed material or drinking water, poultry 0.05-0.1g / kg body weight, livestock 0.03-0.06g / kg body weight, twice a day, 3-5 days as a course of treatment.
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