Cloning and expression of recombinant adhesive protein mefp-2 of the blue mussel, mytilus edulis

a technology of blue mussels and recombinant proteins, applied in the field of cloning and expression of recombinant adhesive proteins of blue mussels, mytilus edulis, can solve the problems of many mussels sacrificed, no conventional glues that can be applied in aqueous environment, no commercial product incorporates any of the other proteins known to be involved in underwater adhesion
US20060029996A1Inactive Publication Date: 2006-02-09THE UNITED STATES AS REPRESENTED BY THE DEPARTMENT OF ENERGY
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Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
THE UNITED STATES AS REPRESENTED BY THE DEPARTMENT OF ENERGY
Publication Date
2006-02-09
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention includes a Mytilus edulis cDNA having a nucleotide sequence that encodes for the Mytilus edulis foot protein-2 (Mefp-2), an example of a mollusk foot protein. Mefp-2 is an integral component of the blue mussels' adhesive protein complex, which allows the mussel to attach to objects underwater. The isolation, purification and sequencing of the Mefp-2 gene will allow researchers to produce Mefp-2 protein using genetic engineering techniques. The discovery of Mefp-2 gene sequences will also allow scientists to better understand how the blue mussel creates its waterproof adhesive protein complex.
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Description

CROSS REFERENCED APPLICATIONS

[0001] This patent application was filed by Applicants on the same day as another patent application filed by Applicants entitled “CLONING AND EXPRESSION OF RECOMBINANT ADHESIVE PROTEIN MEFP-10F THE BLUE MUSSEL, MYTILUS EDULIS”, having Serial No. ______.U.S. GOVERNMENT RIGHTS

[0002] The United States Government may have rights in this invention pursuant to Contract No. DE-AC07-99ID13727 between the U.S. Department of Energy and Bechtel BWXT Idaho, LLC, representing the Idaho National Engineering & Environmental Laboratory (INEEL).TECHNICAL FIELD

[0003] The invention relates to isolated or purified nucleic acid molecules encoding an adhesive protein, for example, Mefp-2 of the blue mussel, Mytilus edulis. Adhesives that can be derived from the present invention can be used in a variety of fields including but not limited to: military applications, construction products, plastics, electronics, automobile and aviation products as well as several biomedical...

Claims

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