Approach to administering ocular medication
a technology for ocular medication and eye drops, which is applied in the field of eye drops and eye drops, can solve the problems of patients with impaired motor skills, caregivers, patients risking improper dosing, and the use of conventional eye drops is difficult even for experienced patients, so as to facilitate the instillation
Inactive Publication Date: 2016-07-07
GLASSER TERRY S DR
View PDF3 Cites 1 Cited by
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Benefits of technology
The FMA provides easy, comfortable, and effective ocular drug delivery, increasing compliance and bioavailability, reducing side effects, and minimizing contamination and injury, while maintaining effective dosing and pH balance.
Problems solved by technology
Conventional eye drops are difficult to use even for experienced patients.
They are more problematic for children, the elderly, patients with impaired motor skills, and caregivers.
Patients risk improper dosing, contamination of the eye dropper container, expensive waste due to spillage, and injury to the eyes from contact with the dropper bottle.
These factors contribute to poor compliance.
These preservatives are known to cause morphological changes to the cornea, conjunctiva, and surrounding areas, which lead to irritation, stinging, burning, epiphora, hyperemia, keratitis, allergic and immune response, and scarring (1).
Subsequent reflex tearing leads to dilution of the medication, which can further alter pharmacodynamics.
At least 80% of the drop is lost from excess tearing, spillage due to overflow from the eye's cul de sac, and rapid drainage through the nasolacrimal duct which increases the risk of systemic side effects (2).
Although these methods are relatively safe, they have not fully addressed the main problems associated with drop delivery.
In addition, they have not been implemented on a large scale (5).
3. Difficult physical manipulation of the eye dropper bottle system by patients and caregivers.
4. Psychological apprehension of the eye drop instillation process.
5. Eye drop preservation process.
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View moreImage
Smart Image Click on the blue labels to locate them in the text.
Smart ImageViewing Examples
Examples
Experimental program
Comparison scheme
Effect test
Embodiment Construction
[0037]Referring to FIGS. 1, 1A, and 2, the present invention comprises a device, a filter matrix applicator (FMA) (10) comprising a flexible elongated handle (15) bonded to a sterile filter matrix (20), which can be medicated or un-medicated, separated by a barrier membrane (30). Flexible elongated handle (15) of a length of approximately but not limited to 2 inches, with a thickness of at least 0.004 inches. It can be made of paper, plastic or another suitable flexible material. The width of the handle can be 0.25 of an inch.
[0038]The barrier membrane (30, 90) can be made of a semi-permeable or impermeable material such as rubber, plastic, waxes, petroleum base product, or another material that is waterproof. As shown in FIG. 7A, once the medicated fluid is placed upon the filter matrix (80), the barrier membrane (90) traps the fluid within the structure of the filter matrix (80) thereby providing a more exact dose of ophthalmic agent to be instilled to the eye. If a pre-medicated ...
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More PUM
Login to View More Abstract
The invention is a device and a method for delivering a dose of a pharmaceutical agent to the eye. The device and method provide a safe and effective way to instill a specified dose of the agent to the eye virtually independent of gravity and posture. The device includes a filter matrix in which the fluid capture and release properties can be modified. The filter matrix is attached to a flexible handle with an impermeable or semipermeable membrane there between.
Description
BACKGROUND[0001]This invention relates to a process and a device for adding a controlled dose of fluid to the eye. Conventional eye drops are difficult to use even for experienced patients. They are more problematic for children, the elderly, patients with impaired motor skills, and caregivers. Patients risk improper dosing, contamination of the eye dropper container, expensive waste due to spillage, and injury to the eyes from contact with the dropper bottle. These factors contribute to poor compliance. In addition, preservatives are added to the drops to provide medicine stability and reduce microbial contamination. These preservatives are known to cause morphological changes to the cornea, conjunctiva, and surrounding areas, which lead to irritation, stinging, burning, epiphora, hyperemia, keratitis, allergic and immune response, and scarring (1).[0002]Subsequent reflex tearing leads to dilution of the medication, which can further alter pharmacodynamics. The quantity and concent...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More Application Information
Patent Timeline
Login to View More Patent Type & AuthorityApplications(United States)
IPC IPC(8): A61F9/00
CPCA61F9/0008A61P27/02
InventorGLASSER, TERRYOBIE, SPENCER
OwnerGLASSER TERRY S DR