Herbal composition for inhibiting melanoma cell metastasis and manufacturing method thereof

a technology of melanoma cell metastasis and herbal composition, which is applied in the direction of medical preparations, pharmaceutical delivery mechanisms, antineoplastic agents, etc., can solve problems such as poor prognosis

Inactive Publication Date: 2020-12-24
ST LOTUS BIOTECH CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Melanoma having metastatic activity is a more dangerous skin cancer, it is also the main cause of death of ski

Method used

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  • Herbal composition for inhibiting melanoma cell metastasis and manufacturing method thereof
  • Herbal composition for inhibiting melanoma cell metastasis and manufacturing method thereof

Examples

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examples

[0018]The following examples are not intended to be limiting, rather they merely present various aspects of the present invention.

[0019]Example 1. Method for preparing the Chinese herbal medicine composition of the present invention

[0020]After 5 kg of Tribulus taiwanense and 5 kg of Houttuynia cordata (Heartleaf Houttuynia Herb) were soaked with 20% edible alcohol for 48 hours, a filtrate was obtained with Silica based columns, and then concentrated at high temperature to increase the concentration by 7 fold to form an extract. Other ten herbs including 1 kg of Lilium brownii var viridulum (Lily Bulb), 2 kg of Atractylodes macrocephala (Rhizome), 2 kg of Poria cocos (Schw) Wolf (Tuckahoe), 1 kg of Ziziphi Spinosae Semen (Spine Date Seed), 3 kg of Adenophora morrisonensis (American silvertop root), 2 kg of Semen Astragali Complanati (Flatstem Milkvetch Seed), 0.5 kg of Zingiber officinale (Fresh Ginger), 3 kg of Pogostemon cablin (Cablin Potchouli Herb), 0.5 kg of Ziziphus jujube (Co...

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Abstract

The present invention relates to a Chinese herbal medicine composition which is prepared from a raw material comprising the following ratio: 1 part by weight of Lilium brownii var viridulum (Lily Bulb), 5 parts by weight of Houttuynia cordata (Heartleaf Houttuynia Herb), 2 parts by weight of Atractylodes macrocephala (Rhizome), 2 parts by weight of Poria cocos (Schw) Wolf (Tuckahoe), 1 part by weight of Ziziphi Spinosae Semen (Spine Date Seed), 3 parts by weight of Adenophora morrisonensis (American silvertop root), 2 parts by weight of Semen Astragali Complanati (Flatstem Milkvetch Seed), 0.5 parts by weight of Zingiber officinale (Fresh Ginger), 5 parts by weight of Tribulus terrestris (Puncturevine Caltrap Fruit), 3 parts by weight of Pogostemon cablin (Cablin Potchouli Herb), 0.5 parts by weight of Ziziphus jujube (Common Jujube), and 0.1 parts by weight of dried Dimocarpus longan (Dried Longan Pulp). The invention also relates to a method of using the herbal composition for inhibiting melanoma cell metastasis. The invention also relates to a process for the preparation of the herbal composition.

Description

TECHNICAL FIELD[0001]The present invention relates to a Chinese herbal medicine composition, which is used in a method for inhibiting melanoma cell metastasis and a method for preparing the same.BACKGROUND OF THE INVENTION[0002]Tumor metastasis is a complex process that usually involves several steps. First, the cancer cells detach from the primary site of a tumor, and migrate to the lymphatic system or blood vessels to destroy the vascular basement membrane and enter the lymph or blood. At this time, the cancer cells must escape from the attack of the immune system in order to survive, and adsorb to distant vascular endothelium, extravasate to a new metastatic site, and then regenerate into a tumor.[0003]Melanoma is highly metastatic, and lung is one of the main organs to which it metastasizes. Melanoma having metastatic activity is a more dangerous skin cancer, it is also the main cause of death of skin cancers, about 75%, the prognosis is not good, and the rate for survival longe...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K36/8967A61K36/78A61K36/888A61K36/725A61K36/23A61K36/481A61K36/185A61K36/53A61K36/77A61K9/00A61P35/04
CPCA61K36/23A61K36/77A61K36/481A61P35/04A61K2236/333A61K36/9068A61K36/78A61K36/185A61K36/888A61K9/0053A61K36/725A61K36/8967A61K36/53A61K36/076A61K2300/00
Inventor LEE, CHIH-CHEN
Owner ST LOTUS BIOTECH CORP
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