Device for rapid detection of infectious agents
a technology for infectious agents and devices, applied in the field of systems for detecting contaminants, can solve the problems of costly recalls, inability to easily perform testing on-site during the manufacturing process, and time-consuming and expensive process for samples for infectious agents
Active Publication Date: 2015-05-05
FUNDAMENTAL SOLUTIONS
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Benefits of technology
Enables rapid, sensitive, and cost-effective detection of infectious agents in biological samples, such as Escherichia coli, within minutes, without the need for culturing, allowing for immediate action and reducing the risk of contamination spread.
Problems solved by technology
Previously, testing of samples for infectious agents was a time consuming and expensive process that was largely divorced from the manufacturing process.
Due to the need for additional culturing or enriching time, and specialized tools and skills, the testing could not easily be performed on-site during the manufacturing process.
As a consequence, the manufacturing process was typically divorced from the testing process, resulting in the need for costly recalls when the testing process later found the presence of infectious agents, and the like.
However, the Rider process suffered from several drawbacks, such as a low signal-to-noise ratio that resulted in the process being undependable for use in large scale testing.
Method used
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[0040]Certain terminology is used in the following description for convenience only and is not limiting. The words “right,”“left,”“lower” and “upper” designate directions in the drawings to which reference is made. The words “inwardly” and “outwardly” refer to directions toward and away from, respectively, the geometric center of the stated component and designated parts thereof. Additionally, the words “a” and “an”, as used in the claims and in the corresponding portions of the specification, mean “at least one.” The terminology includes the words above specifically mentioned, derivatives thereof and words of similar import.
[0041]The present invention provides a portable, self-contained system for rapidly (i.e., within one to five minutes or more) detecting infectious agents, particularly pathogens in biological samples, particularly samples derived from beef, pork, or other meat, poultry, fish, or vegetable matter, although other biological materials, such as healthcare instrument...
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Abstract
A portable system for real time detection of the presence of an infectious agent in a biological sample employs a reagent which detects the presence of a specific infectious agent in the sample, and emits a detectable signal when the reagent reacts with the sample and detects the presence of the infectious agent. A test cartridge has a reaction chamber for receiving the sample and the reagent. The reaction chamber has a predetermined internal geometry and at least one inner surface. Introducing the sample and the reagent into the test cartridge mixes the sample and the reagent. A testing unit receives the test cartridge, and includes a sensor for detecting an emitted detectable signal. The detection of the emitted detectable signal is indicative of the presence of the infectious agent in the sample.
Description
CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This patent application claims the benefit of U.S. Provisional Patent Application Ser. No. 61 / 570,016 filed on Dec. 13, 2011 and entitled “Portable Detection Device,” the disclosure of which is hereby incorporated by reference herein in its entirety and made part of the present U.S. utility patent application for all purposes.BACKGROUND OF THE INVENTION[0002]The described invention relates in general to a system for detecting contaminants in biological samples. More specifically, the present invention relates to a system for detecting infectious agents or pathogens in food samples in real time using a reagent such as a biosensor.[0003]Previously, testing of samples for infectious agents was a time consuming and expensive process that was largely divorced from the manufacturing process. In order to test for the presence of an infectious agent, a sample was typically enriched or cultured. This process requires the presence of a lab, and typ...
Claims
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IPC IPC(8): C12M1/00C12M3/00G01N21/75G01N21/76G01N33/12
CPCG01N21/75G01N21/763G01N33/12G01N2201/0221G01N33/48G01N35/00G01N33/56916G01N2201/12C12Q1/10
InventorWILLIAMS, MARVIN R.MCBRAIRTY, CHARLESPFAUTZ, DANIEL W.ZUPANCIC, THOMAS J.ZENG, LINGCHUNWEIMAN, ANDREWBRODY, RICHARD S.KITTLE, JOSEPHTRUSCOTT, ANTHONYBARANOWSKI, ROBERT
OwnerFUNDAMENTAL SOLUTIONS