The invention relates to a home management method and system for hemodialysis patients based on an informatization technology. The method is characterized in that 1) a management system comprising a patient end, a medical care end and a server is arranged, and the medical care end is wirelessly connected with the patient end through the server or directly connected with the patient end to form a two-way communication loop; 2) the patient end carries out weight measurement reminding, blood pressure measurement reminding, water drinking reminding and medicine taking reminding at regular time so as to enable a patient to carry out weight measurement, blood pressure measurement, quantitative water drinking and quantitative medicine taking at regular time, and if the weight, the blood pressure and the water intake of the patient exceed limits, an alarm is given out; and 3) the medical care terminal monitors the body weight, blood pressure, water intake and medicine taking of the patient and performs health propaganda and education to guide the patient to control the body weight, measure the blood pressure, control the water intake and a medicine taking amount, and the medical care terminal transmits propaganda and education videos or documents to the patient terminal to supervise and urge the patient to conduct learning, observe the learning progress and perform examination reminding. The method and the device have the outstanding substantial characteristic and remarkable progress of capability of monitoring the body weight condition, the water drinking condition and the blood pressure control condition of the patient.