2results about How to "New structure" patented technology

A class of novel mubezhiside compounds, their preparation, and applications, including: mubezhiside A and mubezhiside B. This invention removes impurities directly via macroporous lipid column chromatography after boiling in water, simultaneously removing both aqueous and lipid-soluble impurities with high efficiency. Following impurity removal, silica gel column chromatography is used for purification, allowing for significantly larger sample loading and shorter processing time compared to ODS column chromatography. Preparative HPLC is employed for final purification, greatly improving the purification effect.

Yohimbine derivatives, their preparation methods, and uses. This invention discloses compounds of Formula I and pharmaceutical compositions comprising compounds of Formula I. The compounds of Formula I of this invention, as adrenaline receptor α2A (ADRA2A) antagonists or partial antagonists, can treat and / or prevent inflammatory bowel disease (IBD), particularly ulcerative colitis (UC), Crohn's disease (CD), or enteritis.