The invention discloses medicine-food dual-purpose colorful vermicelli which comprises the following raw materials by mass: 50 to 95% of refined wheat flour, 5-50% of cell wall breaking powder, 0.5-2% of salt, 3-12% of a natural food additive and the right amount of water. The cell wall breaking powder is prepared by low temperature superfine pulverization, and is realized through the technology of superfine powder. After cell wall breaking of medicine-food dual-purpose food materials, human medicine and food absorption rate can be increased, the bioavailability is improved, easy fracture of in the vermicelli production process can be effectively prevented, and the finished product rate can be improved. The preparation technology of the medicine-food dual-purpose colorful vermicelli is as follows: superfine grinding, dosing, homogeneous mixing, kneading dough, curing, pressing, molding, shelving, low temperature drying, off-shelving, section cutting, packaging to obtain the finished product, and can produce all new varieties of high content of colorful vermicelli.