The invention discloses a magnesium-chrome composite spinel brick which is made from synthetical magnesium-chrome spinel sand, magnesia, chromium concentrate and chrome oxide according the weight percentages as follows: taking 65 percent to 70 percent of MgO, 20 percent to 25 percent of Cr2O3, 0.5 percent to 1.2 percent of SiO2, 4 percent to 6 percent of Fe2O3, 2 percent to 4 percent of Al2O3 and 0.5 percent to 1.2 percent of CaO to the material of the number one synthetical magnesium-chrome spinel sand; taking 55 percent to 60 percent of MgO, 30 percent to 35 percent of Cr2O3, 0.5 percent to 1.2 percent of SiO2, 4 percent to 6 percent of Fe2O3, 2 percent to 4 percent of Al2O3 and 0.5 percent to 1.2 percent of CaO to the material of the number two synthetical magnesium-chrome spinel sand; taking 70 percent to 75 percent of MgO, 14 percent to 19 percent of Cr2O3, 0.8 percent to 1.2 percent of SiO2, 4.5 percent to 7 percent of Fe2O3, 2 percent to 4 percent of Al2O3 and 0.8 percent to 1.5 percent of CaO to the material of the number three synthetical magnesium-chrome spinel sand; taking 97 percent to 98.5 percent of MgO, 0.5 percent to 1.3 percent of SiO2, 0.5 percent to 1.3 percent of CaO and 0.2 percent to 0.5 percent of Fe2O3 to the material of the magnesia; taking 50 percent to 60 percent of Cr2O3, 9 percent to 15 percent of MgO, 0.3 percent to 1.5 percent of SiO2, 15 percent to 25 percent of Fe2O3 and 8 percent to 15 percent of Al2O3 to the material of the chromium concentrate; taking 92 percent to 96 percent of Cr2O3 and 4 percent to 8 percent of ZrO to the material of the chrome oxide. The invention has the advantage of having the characteristics of compact structure, thermal shock resistance, anti-scaling off, erosion resistance etc.