Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Medicament for ophthalmology

A technology of eye drops and excipients, applied in the field of research and development of new pharmaceutical products

Inactive Publication Date: 2007-09-05
SCHOOL OF OPHTHALMOLOGY & OPTOMETRY WENZHOU MEDICAL COLLEGE
View PDF2 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, at present, Huangteng has no research and application of ophthalmic topical preparations, only oral preparations or injections are used to treat conjunctivitis; and the traditional medicinal material Huangteng has experience in treating eye diseases among the people, and Huangteng decoction is used to smoke eyes. , or wash the eyes with Huangteng water decoction, which has a good effect of clearing away heat and detoxifying

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] The preparation of embodiment 1, palmatine eye ointment

[0037] Preparation prescription:

[0038] Palmatine 10.0g main ingredient

[0039] Vaseline 80.0g Base

[0040] Liquid paraffin 10.0g base

[0041] Lanolin 8.0g Base

[0042] Make 110g ointment

[0043] Preparation method: Dissolve palmatine in 5ml of water for injection, add matrix, grind thoroughly, and obtain.

Embodiment 2

[0044] Embodiment 2, the preparation of palmatine ophthalmic gel

[0045] Preparation prescription:

[0046] Palmatine 5.0g main ingredient

[0047] Glycerin 12.0g base

[0048] PEG-80 3.0g matrix

[0049] Carbomer 6.2g base

[0050] Sodium bisulfite 0.8g Antioxidant

[0051] Chlorhexidine Gluconate 1.0g Preservative

[0052] Sodium hydroxide Appropriate amount pH adjuster

[0053] Add water for injection to 1000ml

[0054] Make 1000ml gel

[0055] Preparation method: according to the above preparation prescription, weigh carbomer and glycerin, add appropriate amount of water for injection, stir to form a gel matrix; take patellogenin, add appropriate amount of water for injection to dissolve, add PEG-80 and stir evenly; The rattan solution is added into the gel matrix, and then sodium bisulfite and chlorhexidine gluconate are added respectively, and sodium hydroxide is used to adjust...

Embodiment 3

[0056] Embodiment 3, preparation 1 of palmatine eye drops

[0057] Prescription of Padogenin Eye Drops 1:

[0058] Palmatine 20.0g main ingredient

[0059] Dextrose 80g Osmolality regulator

[0060] Phenylalcohol 5.0ml Preservative

[0061] Sodium Thiosulfate 1.0g Antioxidant

[0062] Phosphate buffer, appropriate amount, pH adjuster

[0063] Add water for injection to 1000ml

[0064] Make 1000ml eye drops

[0065] Preparation method: according to the above prescription, weigh glucose and sodium thiosulfate, mix well, add an appropriate amount of water for injection to dissolve, add phenylethanol; add the main drug palmatine to the above solution, add water for injection to the full amount, and add 3g of activated carbon , heated and boiled for 5 minutes, let cool, filtered, subpackaged, each 5ml, that is.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a Chinese medicament for local use on ophthalmology prepared by using Huangtengsu as the main component, wherein the dosages types include eye ointment, eye gel and eye drop. The ophthalmology preparation not only has good effect in treating opthalmitis caused by bacteria and fungus, but also has appreciable protection action to chemical opthalmitis.

Description

technical field [0001] This invention relates to the research and development of new medical products, specifically the preparation of a traditional Chinese medicine ophthalmic topical preparation with palmatine as the main drug. Background technique [0002] Palmatine hydrochloride, also known as palmatine hydrochloride, is an alkaloid substance derived from traditional Chinese medicine, which is extracted and separated from the traditional Chinese medicine Fibraureatinctoria. Palmatine belongs to the proberberine class of benzyltetrahydroisoquinoline alkaloids and has a wide range of biological effects. Current studies have shown that palmatine has significant anti-pathogenic microorganisms and protozoa; it has significant inhibitory effects on a variety of Gram-positive and negative bacteria, and has a significant inhibitory effect on a variety of fungi such as Candida albicans and gypsum-like hairy fungi. , Pei's coloring bacteria, etc. also have a strong inhibitory eff...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/00A61K31/4375A61K36/59A61P27/02
Inventor 张帆
Owner SCHOOL OF OPHTHALMOLOGY & OPTOMETRY WENZHOU MEDICAL COLLEGE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com