Ciclesonide medicinal spraying agent and its preparation method

Abstract

The invention discloses a Ciclesonide medicinal water spray agant and its preparing process, wherein the constituents include (by weight portions): Ciclesonide 1 part, solvent 0.2-4 parts, emulsifying agent 0.04-4 parts, water 0.2-0.4 part. The process requires no casting agents such as CFC and HFC, thereby no pressure containers are needed.

Description

technical field [0001] The invention relates to a medicinal water spray, in particular to a medicine water spray containing ciclesonide. Background technique [0002] Ciclesonide is a drug used to treat respiratory diseases such as asthma and is usually given by mouth or nose. For oral or nasal administration, a propellant is required to atomize ciclesonide to form mist droplets. [0003] It is generally believed that ciclesonide needs to be atomized into droplets with a particle size of about 5 μm through a propellant, so that the drug can be delivered to the bronchopulmonary and other parts of the human body, so as to achieve the therapeutic effect. Therefore, the ciclesonide in the market all adopts freon (CFC) or HFA and so on as propellant, as patent: medical aerosol CN1257421A, promptly uses HFA-134a or 227 as propellant, and freon can cause ozone layer The destruction of freon has been gradually banned. Therefore, it is a subject of great concern to seek a new prope...

AI Technical Summary

Problems solved by technology

Therefore, the ciclesonide in the market all adopts freon (CFC) or HFA and so on as propellant, as patent: medical aerosol CN1257421A, promptly uses HFA-134a or 227 as propellant, and freon can cause ozone layer The destruction of freon has been gradually banned. Therefore, it is a subject of great concern to seek a new propellant to replace Freon.

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