Medicine for treating allergic rhinitis

A kind of medicine and medicine liquid technology, applied in the medicine field of treating allergic rhinitis

Inactive Publication Date: 2007-08-29
YURENTANG MEDICINE DEV CHANGSHA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

There is no patent or literature disclosing the medicine prepared by the prescription in this patent application and its application in the treatment of allergic rhinitis

Method used

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  • Medicine for treating allergic rhinitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Embodiment 1: the preparation of medicinal liquid

[0016] Take 200g of Goose Bubiograss, 200g of Chuanxiong, 40g of Asarum, 40g of Magnolia Magnolia, and 40g of Scutellaria baicalensis. For the above five flavors, take goose not eating grass, chuanxiong, asarum and magnolia, crush them into 4-8mm particles, add 10 times the amount of water, distill for 5 hours to extract volatile oil, and refrigerate for later use; combine Scutellaria baicalensis and distilled medicinal residues, add water and decoct twice , add 10 times of water for the first time, decoct for 1.5 hours, add 8 times of water for the second time, decoct for 1 hour, combine the decoction, filter, and concentrate the filtrate to an extract with a relative density of 1.10 (60°C), add Ethanol to make the alcohol content reach 60%, let it stand for 24 hours, filter, recover ethanol from the filtrate, add distilled water to dissolve the concentrate, refrigerate, filter, and refrigerate the filtrate for later ...

Embodiment 2

[0017] Embodiment 2: the mensuration of medicinal liquid osmotic pressure

[0018] Osmolality was measured by the hematocrit method. Rinse the needle of the syringe with 0.9% sodium chloride solution containing 5% heparin, take fresh blood and put it in the hematocrit tube to the scale of 100, centrifuge at 3000rpm for 30min, discard the plasma, use 0.9% sodium chloride solution as a standard control, and measure 3 batches respectively The osmotic pressure of the liquid. Results The osmotic pressures of the three batches of medicinal solutions met the regulations.

Embodiment 3

[0019] Embodiment 3: the effect of medicinal liquid on guinea pig TDI allergic rhinitis

[0020] Take 30 guinea pigs, weighing 263±40g, regardless of sex, and divide them into 3 groups randomly according to weight stratification. Among them, 1 group was given olive oil as a normal control; the other 2 groups were given 10% TDI olive oil solution (TDI for short) to prepare guinea pig allergic rhinitis model; 5ul on each side, once a day, and then once every other day after 7 days, until the end of administration. On the 15th day of modeling, 15 minutes before administration of olive oil or TDI, the normal control group and the model control group were given normal saline, and the other group was given 96 mg / kg of liquid; the volume was 0.25 ml for nasal administration with a micro-injector / kg, once a day, for 7 days.

[0021] Compared with normal saline, the content of serum IgE and histamine in the nasal mucosa of guinea pig TDI allergic rhinitis model increased significant...

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Abstract

The present invention discloses a Chinese medicine for curing allergic rhinitis. It is made up by using (by wt%) 10-50% of centipede, 10-50% of ligusticum root, 5-20% of asarum, 5-20% of magnolia flower and 5-20% of scutellaria root through a certain preparation process. Said invention also provides its preparation process and concrete steps. Said medicine can be made into nose drops and nose spray preparation.

Description

technical field [0001] The invention relates to the preparation and application of a medicine for treating allergic rhinitis. Background technique [0002] Qing Wu Qian's "Golden Mirror of Medicine", "Selected Edition of Zhang Zanchen's Clinical Experience" published by People's Medical Publishing House in 1981, "600 Commonly Used Chinese Proprietary Medicines" published by Traditional Chinese Medicine Ancient Books Publishing House in 1992, " "Handbook of Clinical Prescriptions", "Integrated Miraculous Prescriptions" edited by Yang Yunxiang, etc., and Xiao Junlou et al. (Journal of External Treatment of Traditional Chinese Medicine 2000; 9(2): 46) disclosed the composition of the prescription of Biyun Powder, but did not disclose the composition of the prescription in this patent application , some of the medicines in the prescription of this patent application are the same as some of the medicines in the prescription of Biyunsan, and some of the medicines are different. T...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/575A61K9/08A61P11/02A61P37/08
Inventor 张佑平朱豫强陈立峰
Owner YURENTANG MEDICINE DEV CHANGSHA
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