Method for preparing general flavone and total alkaloid of sophora flavescens simultaneously

A technology of total flavonoids and total alkaloids of Sophora flavescens, applied in the field of medicine
CN101084989AInactive Publication Date: 2007-12-12石任兵 +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
石任兵
Publication Date
2007-12-12
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a method for simultaneously preparing total flavone extract and total alkaloid extract of Radix sophorae flavescentis. Total flavone extract mainly comprises flavanones (flavanonols) such as norkurarinone, kurarinone, and isokurarinon and other flaconoids such as trifolirhizin, xanthohumol, and kuraridin. Total alkaloid extract mainly comprises matrine n-oxide, N-oxysophocarpine, matrine, sophocarpine, sophoridine, and sophoramine. Total flavone extract and total alkaloid extract can be extracted through one or more of methods of solvent-extraction, solvent extraction, macroporous adsorbent resin, extraction by supercritical fluid, column chromatography, and liquid-liquid countercurrent distribution chromatography. Flavonoid content in total flavone extract is 5-100wt%, wherein the content of norkurarinone, xanthohumol, kuraridin, and trifolirhizin occupies 1-100wt%.Alkaloid content in total alkaloid extract is 5-100wt%, wherein the content of matrine n-oxide, N-oxysophocarpine, matrine and sophocarpine occupies 5-100wt%.
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Description

technical field

[0001] The invention belongs to the technical field of medicine. In particular, it relates to a preparation method and a quality control method for simultaneously preparing the total flavonoid extract and the total alkaloid extract of Sophora flavescens and its application in the fields of pharmaceuticals, health care products and cosmetics. Background technique

[0002] Sophora flavescens is the dried root of Sophora flavescens Ait., a plant of the genus Sophora in the leguminous family. It has the effects of clearing away heat and dampness, killing insects and diuresis. Sophora flavescens contains a large amount of flavonoids and alkaloids, which have antibacterial, insecticidal, antiviral, and anti-inflammatory effects, and are the main material basis for the medicinal effects of flavescens. At present, there is no report on the method of simultaneously extracting and separating the total flavonoid extract and the total alkaloid extract of Sophora flavesc...

Claims

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