Effective part of seesile stemona alkaloid and its application

A technology of effective parts and alkaloids, which is applied in the field of effective parts of alkaloids and pharmaceutical preparations containing effective parts of alkaloids, can solve problems such as unfavorable large-scale production, and achieve low cost, safe production and high purity. Effect

Inactive Publication Date: 2011-02-09
SHANGHAI UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It can be known from the above reports that it is found that a large number of organic solvent extraction methods such as chloroform are used in the current extraction process, and the extraction amount is only 0.33% to 0.44%, which is not conducive to large-scale production

Method used

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  • Effective part of seesile stemona alkaloid and its application
  • Effective part of seesile stemona alkaloid and its application
  • Effective part of seesile stemona alkaloid and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Example 2

Embodiment 2

[0021] Example 3

Embodiment 3

[0023] Alkaloids 1g, stearic acid 15g, lanolin 2g, liquid paraffin 25ml, triethanolamine 2g, glycerin 5ml, distilled water 50ml.

[0024] Take the alkaloids of the basilica and grind it evenly with a small amount of liquid paraffin, and set it aside. Put stearic acid, lanolin and liquid paraffin in a container, heat in a water bath until melted, and continue to heat to 70-80°C; take another triethanolamine, glycerin and distilled water, heat to 70-80°C, slowly pour in stearic acid, etc. The mixture is stirred in the same direction as it is added, and alkaloids are added until emulsified and coagulated. For external use, it is used to kill Demodex mites parasitic on the human body.

[0025] Example 4

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PUM

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Abstract

The present invention relates to extraction process and medicinal application of sessile stemona alkaloid. Sessile stemona alkaloid is extracted through the following steps: 1. extracting with alcohol solution or acid aqua; and 2. purifying with cation exchange resin. The sessile stemona alkaloid product has the sessile stemona alkaloid content over 50 %. The extracting process uses alcohol, no toxic organic solvent and reusable cation exchange resin, and has high safety and low cost. The medicine composition with the sessile stemona alkaloid may be used in treating skin diseases and diseasesof respiratory tract, and in preventing and controlling plant diseases and pests.

Description

technical field [0001] The present invention relates to an effective part of a traditional Chinese medicine and the application of the pharmaceutical preparation thereof, in particular to an effective part of the alkaloids of the plant and a pharmaceutical preparation containing the effective part of the alkaloids of the plant and an application thereof. technical background [0002] Checking the domestic and foreign literature reports on Ceprea, it is found that there are few extraction methods for the total alkaloids of Ceprea. Lin Wenhan {[1] Lin Wenhan, Ye Yang, Xu Rensheng. A Study on the Structure of New Alkaloids in Centipeda Antatus. Organic Chemistry, 1991, 11: 500-3; [2] Lin Wenhan, Xu Rensheng. Zhong Qiongxin. Chemical research on the new alkaloids of Phyllostachys chinensis. Acta Chimica Sinica, 1991, 49: 927-31. [3] Lin Wenhan, Xu Rensheng, Zhong Qiongxin. Chemical research on the alkaloids of Phyllostachys chinensis II. Structural studies of bases. Acta Chemi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/904A61K8/97A61K9/00A61K9/06A61K9/02A61P17/00A61P15/02A61P33/02A61P33/14A61P11/00A61P31/06A61Q19/00A01N65/46A01P17/00A01P7/02A01P7/04C07G5/00
Inventor 张彤张亚中陶建生季光
Owner SHANGHAI UNIV OF T C M
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