9 results about "Chemical research" patented technology

This invention belongs to the field of microbial electrochemistry and single-cell analysis technology, and specifically relates to a femtocoulomb-level single-bacterial surface charge imaging method and its application. This technology is based on electrochemiluminescence microscopy, utilizing the spontaneous enrichment of cationic ECL luminescent molecules by the electrostatic field of the negative charge on the bacterial surface, thereby non-destructively enhancing its ECL signal. By establishing a quantitative relationship between the ECL intensity enhancement ratio and the number of adsorbed molecules, and combining this with COMSOL simulation to determine the thickness of the luminescent layer, it achieves for the first time high-throughput, high spatiotemporal resolution dynamic quantitative measurement of femtocoulomb-level charges on the surface of a single living bacterium. The invented technology has high sensitivity, high resolution, and good biocompatibility, and can be used to reveal bacterial metabolic-charge regulation mechanisms, analyze synergistic electron transport pathways, and screen highly electroactive bacterial subpopulations in situ, providing a key tool for microbial electrochemical research.

The application discloses a reaction optimization method based on double-view contrast learning and double-layer attention, and relates to the technical field of chemical informatics and artificial intelligence. The method comprises the following steps: constructing a double-view molecular representation model, extracting molecular features from a graph structure view and a path sequence view, and pre-training the model through self-supervised contrast learning; constructing a chemical reaction prediction model; pre-training the chemical reaction prediction model by using the extracted molecular features in a chemical reaction data set; taking the reaction prediction model as a proxy model of Bayesian optimization; and realizing the collaborative and rapid optimization of material variables such as reactants, catalysts and solvents, and numerical condition variables such as temperature and concentration. The application effectively solves the problems of missing molecular representation information and low optimization efficiency of high-dimensional mixed variables in the prior art, and significantly speeds up the chemical research and development process.

The invention belongs to the field of chemical research service, and particularly relates to a preparation method of aluminum oxide aerogel with super-hydrophobicity. Comprising the following steps: mixing aluminum salt, deionized water and aluminum powder, and heating and stirring for reaction to form stable aluminum sol; adding a spinning aid into the aluminum sol, uniformly stirring, and standing to obtain an aerogel precursor solution; uniformly mixing and stirring aluminum sol, acid, alcohol, a water repellent agent and a spinning aid to obtain prepolymer sol; spinning the prepolymer sol into an aerogel precursor through electrostatic spinning; and drying the gel precursor to obtain the aluminum oxide hydrophobic aerogel. The aluminum oxide aerogel material prepared by the method has high specific surface area, excellent heat insulation performance and stable super-hydrophobic performance.

The utility model relates to a kind of high-efficiency micro solid powder quantitative metering and transfer tool, it is related to laboratory chemical research field, including: disposable sampling head, disposable sampling head includes outer tube and piston block, piston block is slidably sleeved in outer tube;One end of piston block is connected drive module, drive module is used to drive piston block to slide in outer tube, and the other end of piston block is formed between the outer tube away from drive module and the cavity for accommodating powder.

The application discloses a high-dimensional parameter global optimization chemical intelligent design system and relates to the technical field of chemical design. The high-dimensional parameter global optimization chemical intelligent design system defines the core architecture of the high-dimensional parameter global optimization chemical intelligent design system, integrates four core modules of chemical and material database construction, chemical descriptor extraction, high-dimensional structure-activity relationship prediction model training, intelligent design and reverse deduction, and forms a full-process closed-loop technical scheme of data-feature-model-design. The core benefit is that the traditional chemical research and development is broken through the limitation of scattered data, fragmented algorithm and experience-dependent design, and for the first time, the integrated design from data automatic collection to intelligent scheme output is realized, a systematic solution for high-dimensional parameter global optimization is provided, the protection foundation of the whole technical scheme is laid, and the intelligent level and research and development efficiency of chemical research and development are significantly improved.

The utility model relates to the technical field of chemical research, and discloses a material analysis detector liquid sampler with an anti-splashing baffle, which comprises a pneumatic tube, the bottom of the pneumatic tube is slidably connected with a rubber head, the outer side of the pneumatic tube is fixedly connected with a protective shell, the left side of the protective shell is fixedly connected with a hinge, and the left side of the protective shell is fixedly connected with an anti-splashing baffle. A baffle is fixedly connected to the left side of the hinge, a piston head is slidably connected to the inner side of the air pressure pipe, a piston rod is fixedly connected to the top end of the piston head, a shifting piece is fixedly connected to the top end of the piston rod, and a resistance fixing piece is fixedly connected to the outer side of the shifting piece. According to the utility model, the piston can be pushed to move by using fingers to drive the shifting piece, the absorption amount can be automatically controlled, the convenience is improved by single-hand operation, more operation space can be provided during operation, and an anti-splashing baffle plate is additionally arranged, so that the injury to operators caused by splashing of chemical reagents during operation is prevented.

The invention discloses a reaction optimization method based on double-view comparative learning and double-layer attention, and relates to the technical field of chemical informatics and artificial intelligence. The method comprises the following steps: constructing a double-view molecular representation model, respectively extracting molecular features from a graph structure view and a path sequence view, and carrying out self-supervised contrast learning pre-training on the model; constructing a chemical reaction prediction model; the method comprises the following steps: pre-training a chemical reaction prediction model by utilizing molecular characteristics extracted in a chemical reaction data set, and taking the reaction prediction model as an agent model of Bayesian optimization to realize collaborative rapid optimization of substance variables of reactants, catalysts, solvents and the like and numerical condition variables of temperature, concentration and the like. According to the method, the problems of molecular characterization information loss and low high-dimensional mixed variable optimization efficiency in the prior art are effectively solved, and the chemical research and development process is remarkably accelerated.

A deformable combined funnel stand belongs to the technical field of experimental equipment and comprises a funnel group and a bearing group, the funnel group can be turned over and is used for changing the length and the width of a funnel supporting plate by turning over a funnel supporting plate unit according to needs; the bearing set can be turned over and used for changing the length and the width of the bearing plate by turning over the bearing plate unit according to needs. According to the utility model, the funnel group and the bearing group can be turned over to change the overall length and width, so that the purpose of changing the shape of the occupied space is achieved. After the deformable combined funnel stand is put into use, other experiments can be conveniently carried out cooperatively, the combined form can be changed according to the size of a storage space, the deformable combined funnel stand is convenient to store, and the deformable combined funnel stand is flexible in structural design and use, can support and store a plurality of funnels and receive filtrate containers at the same time, and is high in working efficiency. The filter is suitable for laboratory filtering links in metallurgy, environmental protection and other industries, and has certain application prospects in the field of chemical research.

The invention discloses a seasonal river water environment quality evaluation method based on chemical research service data, and the method comprises the following steps: 1, deploying a low-field nuclear magnetic resonance online detection device on each sampling section, applying a radio frequency excitation pulse to a water sample entering a detection cavity, and collecting a free induction attenuation signal; collecting the one-dimensional nuclear magnetic resonance spectrum vectors of the sampling sections according to seasonal division to form a nuclear magnetic resonance spectrum data set; 2, constructing a one-dimensional convolutional neural network model, and forming a pollutant feature matrix corresponding to each sampling section in each season; and step 3, establishing classic domain matter elements and joint domain matter elements corresponding to each water quality grade according to a water environment quality standard, and summarizing water environment quality evaluation grades of each sampling section in each season to form a seasonal river water environment quality comprehensive evaluation result. According to the invention, on-site rapid detection and automatic spectrogram analysis of organic pollutants are realized, and the problem of poor timeliness of traditional off-line detection is overcome.