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Soothe the nerves Chinese medicinal composition and its applications for preparing climacteric syndrome medicament

A composition and technology of traditional Chinese medicine, applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problems of increasing incidence of endometrial cancer and breast cancer and affecting the wide application of estrogen therapy

Active Publication Date: 2008-08-27
SHANGHAI SEVENTH PEOPLES HOSPITAL +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the limitations of many drug contraindications and the potential risk of increased incidence of endometrial cancer and breast cancer, the wide application of estrogen therapy has been affected.

Method used

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  • Soothe the nerves Chinese medicinal composition and its applications for preparing climacteric syndrome medicament
  • Soothe the nerves Chinese medicinal composition and its applications for preparing climacteric syndrome medicament
  • Soothe the nerves Chinese medicinal composition and its applications for preparing climacteric syndrome medicament

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0027] Preparation Example 1 Mixture I

[0028] Prescription: Salvia miltiorrhiza 150g, Rhizoma Cyperi (made) 100g, Ligustrum lucidum (made) 100g, Sedum notoginseng 250g, mulberry 100g, Xiangyuan 100g, Nocturnal vine 300g.

[0029] Preparation method: the above seven flavors, add 7 times the amount of incense and soak in water for 30 minutes, after fully infiltrating, decoct for 15 minutes, filter, and set aside. Add 8 times the amount of water for the first time and soak the other six herbs for 45 minutes. After fully infiltrating, combine with Cyperus cyperi residues, decoct for 1.5 hours, add 4 times the amount of water for the second time, and decoct for 0.5 hours. Filter the decoction and let it stand for more than 12 hours. Separate the supernatant, concentrate to an appropriate amount, add Cyperus cyperi extract, 2 g of benzoic acid, 0.3 g of ethylparaben and 200 ml of simple syrup, add water to make 1000 ml, stir well, subpackage, and sterilize to obtain.

preparation example 2

[0030] Preparation Example 2 Mixture II

[0031] Soak 60g of Ligustrum lucidum, 60g of mulberry, 250g of Sedum japonica and 200g of Sedum notoginseng in 10 times of water for 1 hour. After fully soaking, decoct for 1.5 hours. Add 3 times the amount of water for the second time and decoct for 0.5 hours. Filter the decoction and let it stand for more than 12 hours. Separate the supernatant, concentrate to an appropriate amount, add 2g of benzoic acid, 0.3g of ethylparaben and 200ml of simple syrup, add water to make 1000ml, stir well, dispense and sterilize.

preparation example 3

[0032] Preparation Example 3 Mixture III

[0033] Soak Cyperus cyperi 60g with 6 times the amount of water for 30 minutes. After fully soaking, decoct for 15 minutes, filter and set aside. Soak 90g of Ligustrum lucidum, 90g of mulberry, 280g of Sedum japonica, 200g of Sedum notoginseng and 100g of Salvia miltiorrhiza in 10 times of water for 1 hour. Add 3 times the amount of water and cook for 0.5 hours. Filter the decoction and let it stand for more than 12 hours. Separate the supernatant, concentrate to an appropriate amount, add 2g of benzoic acid, 0.3g of ethylparaben and 200ml of simple syrup, add water to make 1000ml, stir well, dispense and sterilize.

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Abstract

The invention provides a traditional Chinese medicine compound for tranquilization, which comprises the following components: 10 to 100g of ligustrum lucidum, 10 to 100g of mulberry, 30 to 300g of caulis polygoni multiflori, and 25 to 250g of Herba Sedi Aizoon. The traditional Chinese medicine compound can futher comprise the components as follows: Salvia miltiorrhiza is 15 to 150g, Prepared Nutgrass Galingale Rhizome is 10 to 100g, and Xiangyuan is 10 to 100g. Adding and subtracting can be performed based on the components, and the traditional Chinese medicine compound can further comprise epimedium powder and Rhizoma Curculiginis or comprise tortoise plastron, rhizoma anemarrhenae and phellodendron. The traditional Chinese medicine compound shows the action equivalent to a climacteric-syndrome-relieving tablet in an experimental animal model and clinical cases, and can be used for preparing the drugs for treating climacteric syndrome.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and relates to a traditional Chinese medicine composition for calming the nerves, in particular to a traditional Chinese medicine composition for treating menopausal syndrome. Background technique [0002] Frequent insomnia can cause great harm to the human body, resulting in decreased body immunity and weakened resistance to various diseases; it can cause memory loss and headaches, affecting work, study and life; it can lead to autonomic disorders; it can cause Alzheimer's disease; As well as lead to premature aging and shorten lifespan. Lack of sleep in children will also affect the growth and development of the body. [0003] The number of patients with insomnia is currently increasing year by year. For the treatment of insomnia, sleeping pills are widely used, but long-term use often produces side effects such as tolerance, dependence, and addiction, which aggravate the symptoms ...

Claims

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Application Information

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IPC IPC(8): A61K36/704A61K36/8905A61K36/88A61K36/8964A61K9/10A61K9/16A61K9/48A61K9/20A61P15/12A61P25/20A61K35/56A61K35/586
Inventor 叶景华叶玉妹张国通张和平李琴韵钱燕娟蒋小丰
Owner SHANGHAI SEVENTH PEOPLES HOSPITAL
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