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Use of Sini decoction in preparing medicine for treating hypothyroidism sexual function reduction

A technology of Sini Decoction and sexual function, applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problems of hypothyroidism, sexual function, unsatisfactory curative effect, vertebral-basilar artery insufficiency, etc.

Inactive Publication Date: 2009-02-11
SHANXI UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0028] 2.3 Vertebral-basilar artery insufficiency
[0040] However, the treatment method of supplementing thyroid hormone commonly used in modern medicine is not ideal for the treatment of hypothyroidism and decreased sexual function.
In the pharmacological research on the effect of Sini Decoction on hypothyroid sexual function reduction, the inventors found that the drug can increase the level of sex hormones and have a therapeutic effect on hypothyroid sexual function reduction, which has not been seen in the prior art. A report about the use of Sini Decoction in the treatment of hypothyroidism and decreased sexual function

Method used

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  • Use of Sini decoction in preparing medicine for treating hypothyroidism sexual function reduction
  • Use of Sini decoction in preparing medicine for treating hypothyroidism sexual function reduction
  • Use of Sini decoction in preparing medicine for treating hypothyroidism sexual function reduction

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0093] Take 3Kg of Aconite and 3Kg of Radix Glycyrrhizae, mix them, add water and decoct twice, the first time for 2 hours, the second time for 1.5 hours, combine the decoctions, and filter.

[0094] Get 2Kg of dried ginger and add it into a steam distillation device for steam distillation, extract the volatile oil and store it in another device. Add water to the ginger dregs and decoct for 1 hour. The decoction is combined with the aqueous solution after distilling and separating the volatile oil, and filtered.

[0095] Combine the dried ginger decoction and the aconite licorice decoction, and concentrate to a thick paste with a relative density of 1.20-1.25 (50-60°C).

[0096] Add appropriate amount of auxiliary materials starch and magnesium stearate to the thick paste, mix evenly and make granules, after cooling and drying, spray dried ginger volatile oil, compress into tablets under airtight conditions, and coat to make Sini tablets.

Embodiment 2

[0098] Take 3Kg of Aconite and 3Kg of Radix Glycyrrhizae, mix them, add water and decoct twice, the first time for 2 hours, the second time for 1.5 hours, combine the decoctions, and filter.

[0099] Get 2Kg of dried ginger and add it into a steam distillation device for steam distillation, extract the volatile oil and store it in another device. Add water to the ginger dregs and decoct for 1 hour. The decoction is combined with the aqueous solution after distilling and separating the volatile oil, and filtered.

[0100] Combine the dried ginger decoction and the aconite licorice decoction, and concentrate to a thick paste with a relative density of 1.20-1.25 (50-60°C).

[0101] Add an appropriate amount of auxiliary material starch into the thick paste, mix evenly and make granules, after cooling and drying, spray dried ginger volatile oil, mix evenly, put into capsules to make Sini capsules.

Embodiment 3

[0103] Take 3Kg of Aconite and 3Kg of Radix Glycyrrhizae, mix them, add water and decoct twice, the first time for 2 hours, the second time for 1.5 hours, combine the decoctions, and filter.

[0104] Get 2Kg of dried ginger and add it into a steam distillation device for steam distillation, extract the volatile oil and store it in another device. Add water to the ginger dregs and decoct for 1 hour. The decoction is combined with the aqueous solution after distilling and separating the volatile oil, and filtered.

[0105] Combine the dried ginger decoction and the aconite licorice decoction, and concentrate to a thick paste with a relative density of 1.20-1.25 (50-60°C).

[0106] Add ethanol to the thick paste, stir evenly, let stand for 24 hours, filter, concentrate under reduced pressure, recover ethanol to make a thick paste, add appropriate amount of water to dilute, refrigerate for 24 hours, filter, add appropriate amount of simple syrup and antiseptic Add the above-menti...

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Abstract

The invention relates to an application of a traditional Chinese drug composite, namely a sini decoction, in preparing a drug for treating hypothyroid sexual function reduction. When researching the effect of the sini decoction on rat models with hypothyroid sexual function reduction, the rats are found to experience obvious increase of testosterone level, obvious rise of T level in blood serum after being lavaged with the sini decoction; meanwhile, the level of thyroid hormone gradually recovers, thus indicating that the sini decoction can improve the generating function of rats with hypothyroid sexual function reduction and enhance sexual function by adjusting the secretion of sex hormone. The invention adds the new application of the sini decoction in treating hypothyrosis, especially hypothyroid sexual function reduction and extends indications for the traditional Chinese drug composite, namely the sini decoction.

Description

technical field [0001] The invention relates to a new application of Sini Decoction, a traditional Chinese medicine preparation, in particular to the application of Sini Decoction in the preparation of medicines for treating hypothyroidism and decreased sexual function. Background technique [0002] Sini Decoction originated from "Treatise on Febrile Diseases" and consists of aconite, dried ginger, and licorice. "Treatise on Febrile Diseases" established this prescription for the sun's bad disease turning to Taiyin, or Taiyin, Shaoyin and other cold transformation syndromes. Take it to restore the yang to rescue the adversity, strengthen the body and strengthen the body, so as to overcome the yin and cold, and it is used for the treatment of yin and cold. , Yang Qi declines, and there are symptoms such as rebellious limbs, aversion to cold and tiredness, abdominal urgency, listlessness, diarrhea, vomiting, inability to eat, sweating, and thready pulse. Now it is often used ...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P5/14
Inventor 裴妙荣王晓英
Owner SHANXI UNIV OF CHINESE MEDICINE
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