Device for causing injury of laboratory animal

A component and platform technology, applied in medical science, veterinary equipment, veterinary surgery, etc., can solve problems affecting the progress of spinal cord injury, poor reliability of results, difficult to damage parts, etc., and achieve simple structure, convenient operation, and strong repeatability Effect

CN101375810AInactive Publication Date: 2009-03-04BEIHANG UNIV +2
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Publication Date
2009-03-04
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention provides a device for causing damage to an experimental animal, which comprises a platform and an altitude controller arranged on the platform, and further comprises a striking component, a horizontal bracket and a vertical bracket; the striking component comprises a striking bar, a striking head, a guiding pipe, an electromagnet, a power and a switch; the guiding pipe, which is an open-ended through-tube, is fixed on the horizontal bracket; a cover of the striking bar is arranged in clearance fit with the guiding pipe; one end of the striking bar is connected with the striking head, and the other end of the striking bar is made of ferromagnetic materials and arranged in the magnetic field produced by the electromagnet; the electromagnet and the power are electrically connected with the switch; the altitude controller and the vertical bracket are vertically connected with the horizontal bracket; and the electromagnet is fixed on the vertical bracket. The device causes fixed-point and fixed-amount damage to animal tissue such as spinal cord, reduces artificial errors through mechanized operation, and enhances the repeatability of an experiment.
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Description

technical field

[0001] The invention relates to a device for injuring experimental animals. Background technique

[0002] Spinal cord injury is a serious trauma. There are many cases of spinal cord injury every year, and the number of cases is increasing year by year. Therefore, spinal cord injury is a serious threat to human health and cannot be ignored. However, people still don't know much about the mechanism and treatment methods of spinal cord injury, so the treatment of spinal cord injury is still a worldwide problem.

[0003] In order to study the occurrence mechanism and pathological changes of spinal cord injury well, and to find effective treatment methods for spinal cord injury, it is necessary to establish a standard and ideal animal experimental model. At present, most animal injury experiments use artificial injury methods, such as artificially transecting or half-transecting the spinal cord with a blade; manually releasing weights to hit the spinal cord, but ...

Examples

Embodiment Construction

[0023] Such as figure 1 , figure 2 , image 3 and Figure 4 Shown, the structure of device of the present invention is as follows:

[0024] The device includes a platform 1, a height adjuster 2, a strike assembly, a horizontal support 3 and a vertical support 4; the height adjuster 2 is vertically connected to the platform 1 through a slide rail 18 and can move freely on the platform, and the horizontal support 3 is vertically connected On the height adjuster 2, the vertical support 4 is vertically fixed on the horizontal support 3;

[0025] The strike assembly includes a strike rod 5, a copper strike head 6, a guide tube 7, an electromagnet 8, a power supply and a switch 9; the electromagnet 8 is fixed on the vertical support 4; the electromagnet 8, the power supply and the switch 9 are electrically connected; the guide tube 7 is a hollow tube with openings at both ends, which is vertically fixed on the horizontal support 3; the strike rod 5 is sleeved in the guide pipe ...