Device for causing injury of laboratory animal

Abstract

The invention provides a device for causing damage to an experimental animal, which comprises a platform and an altitude controller arranged on the platform, and further comprises a striking component, a horizontal bracket and a vertical bracket; the striking component comprises a striking bar, a striking head, a guiding pipe, an electromagnet, a power and a switch; the guiding pipe, which is an open-ended through-tube, is fixed on the horizontal bracket; a cover of the striking bar is arranged in clearance fit with the guiding pipe; one end of the striking bar is connected with the striking head, and the other end of the striking bar is made of ferromagnetic materials and arranged in the magnetic field produced by the electromagnet; the electromagnet and the power are electrically connected with the switch; the altitude controller and the vertical bracket are vertically connected with the horizontal bracket; and the electromagnet is fixed on the vertical bracket. The device causes fixed-point and fixed-amount damage to animal tissue such as spinal cord, reduces artificial errors through mechanized operation, and enhances the repeatability of an experiment.

Description

Technical field [0001] The invention relates to a device for causing damage to experimental animals. Background technique [0002] Spinal cord injury is a serious trauma. There are many cases of spinal cord injury every year, and the number of cases is increasing year by year. Therefore, spinal cord injury is a serious threat to human health and cannot be ignored. However, at present, people do not know much about the mechanism and treatment of spinal cord injury, so that the treatment of spinal cord injury is still a worldwide problem. [0003] In order to study the mechanism and pathological changes of spinal cord injury, in order to find an effective treatment for spinal cord injury, it is necessary to establish a standard and ideal animal experimental model. At present, most animal injury experiments use artificial injury methods, such as artificially transection and half-transect the spinal cord with blades; manually release weights to hit the spinal cord, but these methods a...

AI Technical Summary

Problems solved by technology

At present, most animal injury experiments use artificial injury methods, such as artificially transecting or half-transecting the spinal cord with a blade; manually releasing weights to hit the spinal cord, but these methods are difficult to accurately locate and quantitatively control the injury site, and are easy to incorporate the operator's attention. Errors lead to poor reliability of results and poor repeatability of experiments, thus affecting the progress of spinal cord injury research

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