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A technology of composition and regulator, which can be applied in the directions of drug combination, medical preparation containing active ingredient, active ingredient of hydroxyl compound, etc., and can solve the problem of undiscovered coronary heart disease, heart condition, etc.
Inactive Publication Date: 2009-05-13
SOLVAY PHARMA GMBH
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Embodiment 1
[0114] Example 1: Containing K ATP Channel Modulators and CBs x Regulator capsules
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Abstract
The invention is directed to pharmaceutical compositions comprising pharmacologically effective quantities of each of a) at least one KATP channel modulator as a first active agent and b) at least one CBx modulator as a second active agent. The invention further relates to the use of such compositions and to methods of treating, preventing, delaying progression of, delaying onset of and/or inhibiting a variety of disease conditions including obesity, diabetes mellitus, metabolic syndrome, syndrome X, insulinoma, familial hyperinsulemic hypoglycemia, male pattern baldness, detrusor hyperreactivity, asthma, neuroprotection, epilepsy, analgesia, cardioprotection, angina, cardioplegia, arrhythmia, coronary spasm, peripheral vascular disease, cerebral vasospasm, appetite regulation, neurodegeneration, pain - including neuropathic pain and chronic pain - and impotence in mammals and humans by administering such compositions to subjects in need thereof. The invention also is directed to processes of manufacturing such compositions.
Description
technical field [0001] The present invention relates to novel combination treatments for a variety of disease conditions in mammals and humans, including obesity, diabetes, metabolic syndrome, syndrome X, insulinoma, familial hyperinsulinemic hypoglycemia, male Alopecia pattern, detrusor hyperactivity, asthma, neuroprotection, epilepsy, analgesia, cardioprotection, angina pectoris, cardioplegia, arrhythmia, coronary artery spasm, peripheral vascular disease, cerebral vasospasm, appetite regulation, neurodegeneration, Pain - including neuropathic pain and chronic pain - and impotence. The present invention also relates to ATP Channel Modulators and CBs x Novel pharmaceutical compositions of modulators and said pharmaceutical compositions for preventing various disease states, treating various disease states, delaying the progression of various disease states, delaying the onset of various disease states and / or inhibiting various disease states conditions including obesity, d...
Claims
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