Detection method of xanthi rhinitis capsules

Abstract

The invention discloses a quality control method of Xanthium rhinitis capsules, which uses high-performance liquid chromatography to measure the content of baicalin, uses octadecylsilane bonded silica gel as a filler, and acetonitrile with a volume ratio of 20:80 0.3% phosphoric acid solution is the mobile phase, the flow rate is 1ml / min; the detection wavelength is 275-276nm; the column temperature is 35°C; the reference substance solution and the test solution are accurately drawn respectively, injected into the liquid chromatograph, measured, and calculated according to the measurement results , that is, the content of baicalin in Xanthium rhinitis capsule content. Based on the qualitative identification of the original quality standard TLC, the quality control method adds the content determination method of baicalin, which makes the quality control of Xangerzi Biyan Capsules more accurate and effective, and thus more conducive to ensuring its clinical curative effect; Moreover, the content determination method is simple in operation, accurate in result, good in precision, stability, reproducibility and the like.

Description

technical field [0001] The invention belongs to the technical field of quality control of pharmaceutical preparations, and in particular relates to a quality control method of cocklebur rhinitis capsules. Background technique [0002] Xanthium Rhinitis Capsules are recorded in the fourteenth volume of the Ministry of Health's drug standards for traditional Chinese medicine prescriptions. Chronic rhinitis, sinusitis, allergic rhinitis, etc. [0003] Xanthium Rhinitis Capsules are made of Xanthium extract powder 180g, gypsum extract powder 1.76g, Angelica dahurica extract powder 62.1g, borneol 30g, magnolia flower volatile oil 4ml, menthol 15g, magnolia flower extract powder 72.2g, Scutellaria baicalensis Extract powder 25.3g is a capsule preparation made from raw materials. The preparation method is: in addition to the volatile oil of magnolia flower, mix borneol, menthol and appropriate amount of starch, grind into fine powder, mix with the above-mentioned extract powders, ...

AI Technical Summary

Problems solved by technology

Since the quality of medicines is closely related to human health, the requirements for quality control of medicines are getting higher and higher, and safety and efficacy are equally important. The quality control is not accurate and reliable enough, does not meet the needs of the development of modern medicine, and needs to be further improved

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