Quality control method of siberian cocklebur fruit capsule for treating rhinitis

Abstract

The invention discloses a method for controlling the quality of a fructus xanthil rhinitis capsule. The content of scutelloside is measured by the efficient liquid chromatography, and octadecylsilane chemically bonded silica is used as a filling agent; an acetonitrile-0.3 percent phosphoric acid solution is of a moving phase, the volume ratio thereof is 20 to 80, and the flow speed is 1ml / min; the detection wavelength is from 275 to 276nm; the column temperature is 35 DEG C; a check variety solution and a test article solution are respectively precisely absorbed and are injected into a liquid chromatograph to be tested, and calculation is performed according to a measurement result, thereby gaining the content of the scutelloside in the fructus xanthil rhinitis capsule content. On the basis of the original quality standard thin layer chromatography qualitative discrimination, the quality control method is additionally provided with the method for measuring the content of the scutelloside, and causes the quality control of the fructus xanthil rhinitis capsule to be much more accurate and efficient, thereby benefiting more to the exertion of the clinical efficacy of the fructus xanthil rhinitis capsule; and the content measurement method has simple operation, accurate result, favorable precision, stability and reproduction quality, etc.

Description

technical field [0001] The invention belongs to the technical field of quality control of pharmaceutical preparations, and in particular relates to a quality control method of cocklebur rhinitis capsules. Background technique [0002] Xanthium Rhinitis Capsules are recorded in the fourteenth volume of the Ministry of Health's drug standards for traditional Chinese medicine prescriptions. Chronic rhinitis, sinusitis, allergic rhinitis, etc. [0003] Xanthium Rhinitis Capsules are made of Xanthium extract powder 180g, gypsum extract powder 1.76g, Angelica dahurica extract powder 62.1g, borneol 30g, magnolia flower volatile oil 4ml, menthol 15g, magnolia flower extract powder 72.2g, Scutellaria baicalensis Extract powder 25.3g is a capsule preparation made from raw materials. The preparation method is: in addition to the volatile oil of magnolia flower, mix borneol, menthol and appropriate amount of starch, grind into fine powder, mix with the above-mentioned extract powders, ...

AI Technical Summary

Problems solved by technology

Since the quality of medicines is closely related to human health, the requirements for quality control of medicines are getting higher and higher, and safety and efficacy are equally important. The quality control is not accurate and reliable enough, does not meet the needs of the development of modern medicine, and needs to be further improved

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