Taxus nontoxic extract process

Abstract

The invention relates to a taxus nontoxic extract process, comprising the following steps: (1) grinding trunks and roots of taxus into taxius dried powders according to the weight proportion of 4:1; (2) putting 2kg of taxus raw material together with 8kg of liquor with alcohol content of 55-65 percent into a sealed glass bottle at the temperature of 25-40 DEG C; (3) respectively adding 250g of liquor and 100g of taxus dried powders at the seventh day, the 14th day and the 21th day of immersion, then stirring, simultaneously heating to the temperature of 50-60 DEG C till the liquor becomes maroon in color, finishing the immersion processing when the liquor is pink after drying by dripping on the ground; (4) filtering, removing residues, sealing and precipitating for more than 48 hours, removing precipitates, heating the immersed finished product to the temperature of 50-100 DEG C by using a container, vacuum extracting, keeping wet extract and drying the wet extract to obtain taxol alcohol extract. The invention has the advantages of: being capable of preventing tumors in advanced when used as an additive of a health care product, and treating tumors and relieving the pain of patients when used as an additive of antineoplastic Chinese patent drugs.

Description

technical field [0001] The invention relates to the field of additives for food, health care products and medicines, in particular to a process for the non-toxic extract of yew. Background technique [0002] At the briefing meeting of the Cancer Prevention and Propaganda Week held in 2005, the Ministry of Health reported that at present, the average annual number of cancer cases in my country is about 1.8 million to 2 million, and the number of deaths is about 1.4 million to 1.5 million; In the middle of the year, the number of cancer deaths in my country will double. Experts predict that the number of cancer deaths in China will exceed 4 million in 2020. Among the malignant tumor mortality rates, lung cancer ranks first among male and female malignant tumors. [0003] The medicinal value of yew is mainly reflected in its extract - secondary metabolite derivative - paclitaxel. Based on the research results of Dr. Fang Weishuo (Fang Weishuo—graduated from Peking Union Medica...

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Problems solved by technology

[0005] At present, the price of paclitaxel with 98% purity in the international market is 400,000 to 600,000 US dollars per kilogram, and the price of paclitaxel with 70% purity in my country is 1.6 to 1.8 million yuan per kilogram, which is more expensive than the price of gold.

[0006] The current use of yew in the world is mainly based on extracting paclitaxel from yew, making it into injections, and using it in the form of injection chemotherapy. The degree of secondary damage caused by chemotherapy to patients is obvious to all. There are many Chinese medicines in China. Use of yew A small amount of yew raw materials can be added to various traditional Chinese medicine prescriptions, but it should not be used in excess, for fear that its toxicity will cause other harm to patients

[0007] At present, there is no very good and effective method to treat the pain of tumor patients in our country. The analgesics currently used are mainly western medicines, but their disadvantages are that long-term use will cause dependence and drug resistance in patients, while traditional Chinese medicines do not have this difficulty. can solve this shortcoming

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