Cell processing liquid for diagnosis of liquid based cytology

A cytology and treatment liquid technology, applied in the field of cell treatment liquid, can solve the problems of cell damage, poor removal of impurities such as red blood cells, etc., and achieve the effect of low cost

Inactive Publication Date: 2011-01-26
南京卡博生物科技有限公司
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  • Summary
  • Abstract
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  • Claims
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AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to provide a cell treatment solution for liquid-based cytology diagnosis, which solves the problem that the current cell treatment solution has damage to cells and has a poor effect on removing impurities such as tissue fragments, mucus, and red blood cells that have no diagnostic value in the sample. question

Method used

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Examples

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Embodiment Construction

[0007] A cell treatment solution for liquid-based cytology diagnosis according to an embodiment includes: sulfonic acid substances, non-ionic osmotic pressure regulators, polyethylene glycol octylphenyl ether, formaldehyde and ethanol. The sulfonic acid is sulfuric acid. A nonionic osmotic pressure regulator is dimethylurea. Wherein, the content of sulfuric acid is 2g / L, the content of dimethyl urea is 0.5g / L, the content of polyethylene glycol octyl phenyl ether is 6g / L, the content of formaldehyde is 3g / L, and the content of ethanol is 24g / L.

[0008] The sulfuric acid with a content of 2g / L in the cell treatment solution can control the pH value at about 4, and the polyethylene glycol octyl phenyl ether with a content of 6g / L can make tissue fragments and mucus without diagnostic value within this pH range. Impurities such as red blood cells and red blood cells are selectively and quickly destroyed and dissolved, and at the same time, the background of the slices can be m...

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Abstract

The invention relates to a cell processing liquid for diagnosis of liquid based cytology, which comprises a sulfonic acid material, a non-ion type osmotic pressure regulator, polyoxyethylene octyl phenyl ether, formaldehyde and ethanol, wherein the sulfonic acid material is at least one of sulfuric acid, methanesulfonic acid or para-toluenesulfonic acid, and the non-ion type osmotic pressure regulator is dimethyl urea. The invention solves the problems that the current cell processing liquid can damage the cells and has a poor effect of removing impurities such as fragments of tissue, mucus, red blood cells and the like which have no values for diagnose, and the invention has low cost.

Description

technical field [0001] The invention belongs to the field of cell treatment liquid and relates to a cell treatment liquid for liquid-based cytology diagnosis. Background technique [0002] At present, the cell treatment solution is harmful to the cells, which is not conducive to further medical testing, and when encountering samples containing more blood cells and mucus, it is not effective in removing impurities such as tissue fragments, mucus, and red blood cells that have no diagnostic value, resulting in The background of the prepared cell smear is not clear, the number of cells is reduced, and the rate of misdiagnosis and missed diagnosis increases. Contents of the invention [0003] The purpose of the present invention is to provide a cell treatment solution for liquid-based cytology diagnosis, which solves the problem that the current cell treatment solution has damage to cells and has a poor effect on removing impurities such as tissue fragments, mucus, and red blo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12Q1/02
Inventor 吕军赵世鹏
Owner 南京卡博生物科技有限公司
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