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Application of campanumoea polysaccharide in preparation of medicament and health care food

A technology for health food and drug preparation, applied in the fields of health care development and medicine, can solve the problems of patients' social activity decline, affect the quality of life, neurotransmitter disorders, etc., to improve cognitive dysfunction, enhance hematopoietic function, and promote trauma. repaired effect

Active Publication Date: 2012-07-11
THE KEY LAB OF CHEM FOR NATURAL PROD OF GUIZHOU PROVINCE & CHINESE ACADEMY OF SCI
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Neuronal damage, neurotransmitter imbalance, neuronal plasticity inhibition may be caused by microembolism, anesthesia, hypoxia, hypoxia, hypoperfusion, and systemic inflammatory response after surgery, which may lead to postoperative cognitive dysfunction, mental and behavioral disorders, and Sleep cycle disturbances caused by anxiety, fear, euphoria, and apathy increase patient hospitalization time and medical costs, and lead to decreased social mobility, seriously affecting quality of life

Method used

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  • Application of campanumoea polysaccharide in preparation of medicament and health care food
  • Application of campanumoea polysaccharide in preparation of medicament and health care food
  • Application of campanumoea polysaccharide in preparation of medicament and health care food

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Experimental program
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Effect test

Embodiment Construction

[0042] Implementation 1. Polysaccharides from Codonopsis pilosula as a preparation to promote postoperative recovery

[0043] Codonopsis pilosula medicinal material is extracted with water and precipitated with alcohol to prepare crude polysaccharide of Codonopsis pilosula; further purified by column chromatography to prepare pure polysaccharide CJP-1 of Codonopsis pilosula. Then adopt conventional technology to prepare dosage forms such as tablets, capsules and oral liquids with the polysaccharide of Codonopsis pilosula as a raw material.

[0044] Implementation 2. Dosage study

[0045] The experimental part refers to "Chinese Medicine Pharmacological Research Methodology". The acute toxicity test shows that the mice did not die after being fed with a dose of 3.75g / kg of Codonopsis polysaccharide (185 times the adult dose), indicating that Codonopsis polysaccharide is safe and non-toxic side effect.

[0046] Implementation 3. Research on the effect of drugs on improving cog...

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Abstract

The invention discloses application of campanumoea polysaccharide in preparation of medicament and health care food, which relates to the technical field of medicine and health care. The campanumoea polysaccharide is characterized by being used for preparing medicament and medicinal preparation for promoting functional recovery after various medical, surgical and obstetric operations and during tumor chemotherapy and burn / scald treatment, and preparing health care food or health care additives with health care effect on metabolism reduction, valetudinarianism, gastrointestinal function decline, inappetence and low immunity. Moreover, the prepared medicament and food have the characteristics of high efficiency, no toxicity and high safety.

Description

technical field [0001] The invention belongs to the technical field of medicine and health care development, and relates to a new medical application of Chinese herbal medicine Codonopsis pilosula, specifically the application of Codonopsis codonopsis polysaccharide in preparing medicine and health food. Background technique [0002] Surgery is a "double tough sword". While treating, it will also cause certain trauma to the body, which will cause a series of endocrine and metabolic changes, increase consumption, and also cause bleeding, pain, edema, constipation, infection, etc. Serial complications. Neuronal damage, neurotransmitter imbalance, neuronal plasticity inhibition may be caused by microembolism, anesthesia, hypoxia, hypoxia, hypoperfusion, and systemic inflammatory response after surgery, which may lead to postoperative cognitive dysfunction, mental and behavioral disorders, and Sleep cycle disorders caused by anxiety, fear, euphoria, and apathy increase patient ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/715A61P17/02A61P39/00A61P25/00A61P7/00A61P7/06A61P1/14A61P35/00A61P39/02A61P37/04A23L1/29A23L1/30A23L33/105A23L33/125
Inventor 杨娟张振东彭梅吴兰芳景永帅杨小生
Owner THE KEY LAB OF CHEM FOR NATURAL PROD OF GUIZHOU PROVINCE & CHINESE ACADEMY OF SCI
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