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Interventional medical appliance and manufacturing method thereof

A medical device and drug technology, applied in the field of medical devices, can solve the problems of delaying vascular endothelialization, reducing the incidence of restenosis in the stent, etc., and achieve the effects of inhibiting proliferation, reducing the incidence rate, and promoting growth

Inactive Publication Date: 2012-04-04
SHANGHAI MICROPORT MEDICAL (GROUP) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Therefore, the existing drug stents that inhibit intima or media hyperplasia cannot minimize the incidence of in-stent restenosis
In addition, inhibition of vascular intima or medial hyperplasia will also lead to the problem of delayed vascular endothelialization, and incomplete endothelialization of blood vessels may cause late thrombosis

Method used

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  • Interventional medical appliance and manufacturing method thereof
  • Interventional medical appliance and manufacturing method thereof
  • Interventional medical appliance and manufacturing method thereof

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Embodiment Construction

[0039] In order to enable those skilled in the art to better understand the technical solutions in the present application, the technical solutions in the embodiments of the present application will be clearly and completely described below in conjunction with the drawings in the embodiments of the present application. Obviously, the described The embodiments are only some of the embodiments of the present application, but not all of them. Based on the embodiments in this application, all other embodiments obtained by persons of ordinary skill in the art without creative efforts shall fall within the scope of protection of this application.

[0040] An embodiment of the present application provides an interventional medical device, including: a stent body, wherein: a drug release structure is provided on the surface of the stent body, and the drug in the drug release structure is a drug that inhibits the proliferation of adventitial fibroblasts.

[0041] An example:

[0042] ...

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Abstract

The invention discloses an interventional medical appliance and a manufacturing method thereof. The interventional medical appliance comprises a bracket body, wherein the surface of the bracket body is provided with a medicament releasing structure; and a medicament in the medicament releasing structure is a medicament for restraining proliferation of adventitial fibroblasts. When the interventional medical appliance is transplanted into a human body, the medicament for restraining the proliferation of adventitial fibroblasts can be slowly released into vessel wall cells contacted with the bracket body, so that the proliferation of the adventitial fibroblasts can be restrained, the compensatory expansion of vessels is promoted, and the incidence rate of restenosis in the bracket is lowered.

Description

technical field [0001] The present application relates to the technical field of medical devices, in particular to a drug-containing interventional medical device and a preparation method thereof. Background technique [0002] In recent years, in order to avoid the occurrence of in-stent restenosis after interventional treatment, the stent implanted in the human body is coated with a drug coating. Most of the currently used drug stents carry drugs that inhibit the proliferation of vascular intima or media, for example: rapamycin, paclitaxel and their derivatives, etc. When the stent carrying the above drugs is implanted in the human body, the stent will Continuously release drugs that inhibit the proliferation of the intima or media of the vessel to the vessel wall to reduce the incidence of in-stent restenosis. [0003] Studies have shown that the formation mechanism of intravascular restenosis is not only related to intima or media hyperplasia after vascular injury, but a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/82A61L31/10A61L31/16
CPCA61F2240/00A61F2/82A61L2300/416A61L31/08A61F2002/0086A61L31/16A61L31/10A61L31/146A61L2400/00A61L2420/02A61L2420/06B05B17/06B05D1/02B05D1/18
Inventor 蔡煦张大东胡燕黄鹏李俊菲乐承筠唐智荣罗七一
Owner SHANGHAI MICROPORT MEDICAL (GROUP) CO LTD
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