363 results about "Cell contact" patented technology

The present application discloses a cell contact structure, a semiconductor device, and a method for fabricating the semiconductor device. The cell contact structure includes a contact layer positioned on a substrate and enclosed by a plurality of bit line structures and a plurality of partition layers; and a liner layer positioned between the contact layer and the substrate, between the contact layer and the plurality of bit line structures, and between the contact layer and the plurality of partition layers. A top surface of the contact layer and a top surface of the liner layer are substantially coplanar. The liner layer includes doped polycrystalline silicon, doped polycrystalline germanium, or doped polycrystalline silicon germanium. The contact layer includes tungsten, titanium, or titanium nitride.

A memory device includes a substrate, a word line buried in the substrate and extending in a first direction, a word line cap layer over the word line, a landing pad over and in contact with the substrate and the word line cap layer, a cell contact over and in contact with the landing pad, and a bit line over the word line and extending in a second direction perpendicular to the first direction.

Methods to identify compounds that accelerate a transition of a cell from an acute hypoxic state to a hypoxic adaptive state include contacting a test compound with the cell in the acute hypoxic state, and detecting the transition of the cell from the acute hypoxic state to the cell in the hypoxic adaptive state and measuring the length of time of the transition; wherein the length of time of the transition is shorter in the presence of the test compound relative to the absence of the test compound, thereby identifying the compound that accelerates the transition of the cell from an acute hypoxic state to a hypoxic adaptive state. The compounds identified by the methods can be used to treat acute hypoxia and acute ischemia.

The utility model relates to the field of batteries, and discloses a collector plate and a battery, the collector plate comprises a plate body, first protrusions, second protrusions and third protrusions, the plurality of first protrusions are uniformly arranged on the plate body at intervals, liquid injection ports are formed between the adjacent first protrusions, the liquid injection ports are formed in the plate body in a penetrating manner, and the second protrusions are arranged on the plate body. The second protrusions are arranged at the ends, facing the center of the disc body, of the first protrusions, and the third protrusions are arranged at the ends, away from the center of the disc body, of the first protrusions. The first protrusions are arranged on the disc body, the second protrusions and the third protrusions are arranged at the two ends of the first protrusions respectively, the first protrusions, the second protrusions and the third protrusions form the bosses, and the bosses can make full contact with the flattened tabs and can flatten the tilted tabs again, so that the tabs make full contact with the tabs, and the tab flattening efficiency is improved. And short circuit caused by poor cell contact is prevented.

The present application discloses a cell contact structure, a semiconductor device, and a method for fabricating the semiconductor device. The cell contact structure includes a contact layer positioned on a substrate and enclosed by a plurality of bit line structures and a plurality of partition layers; and a liner layer positioned between the contact layer and the substrate, between the contact layer and the plurality of bit line structures, and between the contact layer and the plurality of partition layers. A top surface of the contact layer and a top surface of the liner layer are substantially coplanar. The liner layer includes doped polycrystalline silicon, doped polycrystalline germanium, or doped polycrystalline silicon germanium. The contact layer includes tungsten, titanium, or titanium nitride.

The present application discloses a method for injecting exogenous substances into cells based on a single-cell operation device. The single-cell operation device includes a stage carrying a sample, a first probe, a first electrode arranged on the first probe, and a second electrode electrically connected to the sample. The first probe is an elongated hollow structure and includes a front end and a rear end. The front end of the first probe acts on the cell membrane of the target cell in the sample. The method for injecting exogenous substances into cells includes: step S100, establishing a first electric field between the first electrode and the second electrode, and the first probe detects the change of the first electric field signal during the movement to determine whether the front end of the first probe is in contact with the target cell; step S200, the front end of the first probe moves relative to the sample to penetrate the cell membrane of the target cell; step S300, establishing a second electric field between the first electrode and the second electrode, and the exogenous substance is injected into the target cell under the action of the second electric field. The technical solution in the present application has the advantages of high precision, low damage, high throughput, and multifunctionality.

A cell carrier (1) for high-voltage storage cells is provided, which comprises absorption structures (4) and a cell contacting system (5), a cell monitoring system (6), and at least one cell receiving structure (7) on the underside (3) of the cell carrier (1). The cell receiving structure (7) is designed to releasably receive a cylindrical battery cell (2).

A non-volatile memory device comprises a substrate, a mold structure that includes gate electrodes stacked on the substrate and mold insulating layers alternately stacked with the gate electrodes, a cell contact on the substrate, wherein the cell contact is electrically connected to a selection gate electrode of the gate electrodes and is not electrically connected to a non-selection gate electrode of the gate electrodes, an insulating ring on the substrate, wherein the insulating ring is between the non-selection gate electrode and a sidewall of the cell contact and is in contact with the non-selection gate electrode, and a high dielectric constant layer between respective ones of the gate electrodes and the mold insulating layers, wherein the insulating ring includes a first portion that overlaps the high dielectric constant layer in a vertical direction, and a second portion that does not overlap the high dielectric constant layer in the vertical direction.

The present application discloses a cell contact structure, a semiconductor device, and a method for fabricating the semiconductor device. The cell contact structure includes a contact layer positioned on a substrate and enclosed by a plurality of bit line structures and a plurality of partition layers; and a liner layer positioned between the contact layer and the substrate, between the contact layer and the plurality of bit line structures, and between the contact layer and the plurality of partition layers. A top surface of the contact layer and a top surface of the liner layer are substantially coplanar. The liner layer includes doped polycrystalline silicon, doped polycrystalline germanium, or doped polycrystalline silicon germanium. The contact layer includes tungsten, titanium, or titanium nitride.

Disclosed in the present application are a cells contact piece, a cells contact system and a battery pack. The cells contact piece comprises cells contact sub-pieces and flexible conductive connecting pieces, wherein a plurality of cells contact sub-pieces are provided, and the plurality of cells contact sub-pieces are respectively used for collecting working signals of a plurality of battery cell groups; and a connecting piece is provided between every two adjacent cells contact sub-pieces, two ends of each connecting piece are respectively connected to two cells contact sub-pieces adjacent thereto, and each connecting piece has a first bending structure, the first bending structure being configured to deform when two battery cell groups move away from or close to each other.

Cell contacting element (2, 220) for electrical contacting at least one energy storage cell (3) of an energy storage module (1), in particular an energy storage module for a vehicle, comprising an electrically conductive base body (211, 221) with at least one contact surface (212, 222) for electrical contacting a terminal (302) wherein the base body (211, 221) is coated in a partial area (214, 224) with a planar coating (217, 227).

To design a cell contacting system for an electrochemical module comprising multiple cell groups, each comprising multiple electrochemical cells, wherein each electrochemical cell has a first cell terminal and a second cell terminal, wherein the cell terminals are contacted by means of electrically conductive contact areas that follow a contacting direction onto the respective cell terminal, wherein the first cell terminals of a first cell group have the highest electrical potential and the second cell terminals of a second cell group have the lowest electrical potential and In order to create a system which at least partially overcomes the problems of known cell contacting systems, wherein the first cell terminals of the first cell group are electrically connected to a first busbar and the second cell terminals of the second cell group are electrically connected to a second busbar, wherein the electrochemical cells of the first cell group follow one another along a longitudinal direction and the electrochemical cells of the second cell group follow one another along the longitudinal direction and at least one of the busbars has a main surface which extends parallel to the longitudinal direction, it is proposed that the main surface of the at least one busbar extends substantially parallel to the contacting direction of the electrochemical module.

This document provides methods and materials for manipulating telomere length. For example, this document provides methods and materials for using one or more agents that can manipulate (e.g., increase or decrease) telomere length. In some cases, one or more agents that can increase telomere length can be contacted with a cell to increase telomere length in that cell. For example, one or more agents that can increase telomere length can be administered to a mammal having one or more TBDs to increase telomere length in cells within the mammal (e.g., to treat the mammal). In some cases, one or more agents that can decrease telomere length can be contacted with a cell to decrease telomere length in that cell. For example, one or more agents that can decrease telomere length can be administered to a mammal having a disease or disorder associated with increased telomere synthesis and / or increased telomerase activity to decrease telomere length in cells within the mammal (e.g., to treat the mammal).

The present invention provides a method and device for stringing battery cells, wherein the method for stringing battery cells comprises the following steps: setting a first adhesive tape on the reverse side of the battery cell along a direction intersecting with a secondary grid line; turning over the battery cell; setting a second adhesive tape on the front side of the battery cell along a direction intersecting with the secondary grid line; cutting the welding tape into welding tape segments; placing the welding tape segments on the first adhesive tape of the previous battery cell and on the second adhesive tape of the next battery cell to form a battery string; curing the battery string so that the secondary grid line on the battery cell contacts and is fixedly connected with the welding tape segments; the stringing method proposed by the present invention is simpler. Compared with the existing main grid-free string welding scheme, the present invention does not require flux, and alloying does not need to be formed between the welding tape and each secondary grid line of the battery cell. At the same time, the battery string can be subjected to EL detection after being cured, and will not cause the entire battery panel after lamination to be scrapped, and the difficulty of rework is small.

The present application provides a semiconductor device and a method for fabricating the same. The device includes a substrate with a first top surface, first and second gate electrodes within the substrate, a first barrier layer, and a second barrier layer over the first barrier layer and the first gate electrode. A gate capping layer is placed over the second gate electrode, and a cell contact structure is disposed on the first top surface. The second gate electrode is above the first gate electrode, wherein the first gate electrode consists of a first member surrounded by the first barrier layer and a second member extending toward the first top surface, protruding from the first barrier layer. The second gate electrode surrounds the second barrier layer and the second member of the first gate electrode.

The present invention relates to reagent-coated cover slips and methods of using them to carry out one or more reactions. The present invention provides methods using reagent-coated cover slips to carry out a test on a carrier slide. The present invention provides methods where sample cells are immobilized on a carrier slide and a test is carried on the carrier slide. The present methods carry out one or more chemical reactions in the embedded sample cells on a carrier slide by contacting reagent-coated cover slips with sample cells immobilized on the carrier slide to result in a reaction product on the carrier slide.

A CCS assembly (10), a battery module (1), a battery (2) and an electrical device are provided and relate to the technical field of batteries. The CCS assembly includes a first insulation bracket (101), at least one bus bar (102), and an FPC board (103). The first insulating bracket (101) is configured to mount a plurality of cells (20) and is provided with at least a positioning post (1011). The bus bar (102) is configured to be connected to the cells (20). The bus bar (102) is arranged on the first insulating bracket (101) and is provided with a first through hole (1021). The bus bar is sleeved on the positioning post (1011) through the first through hole (1021). The FPC board (103) is connected to the bus bar (102) and is configured to transmit operating signals of the bus bar to a BMS board (30).

A power storage device is provided with: a pair of power storage cells arranged so as to face each other in a first direction; a cooling member that is in thermal contact with the pair of power storage cells in the second direction and cools the pair of power storage cells; and a heat insulating member disposed between the pair of power storage cells. The cooling member has: a pair of power storage unit contact parts that are in thermal contact with each of the pair of power storage units in the second direction; and a connecting portion that connects the pair of power storage cell contact portions to each other. The thermal resistance of the connecting portion is greater than the thermal resistance of the power storage unit contact portion.

The present invention provides a nucleic acid for transfection in which a nucleic acid targeted for introduction into a cell and a cell membrane-permeable group are linked together, the cell membrane-permeable group contains a perfluoroalkyl group having 2 to 10 carbons, and the perfluoroalkyl group may have one to five ether-bonded oxygen atoms between the carbon atoms, and also provides a nucleic acid transfection method that involves bringing the nucleic acid for transfection into contact with a cell to introduce the nucleic acid into the cell.

The utility model relates to a turnover assembly and a battery piece turn-over mechanism, the turnover assembly comprises a turnover unit and a suction cup arranged on the turnover unit and used for adsorbing a product, the suction cup comprises a body, a negative pressure hole and a base plate, the base plate is arranged on the surface, facing the product to be turned over, of the body, and the negative pressure hole is formed in the base plate. The negative pressure hole is arranged on the surface of the body in an area not covered by the backing plate. According to the utility model, the sucking disc is adopted to suck the battery piece, and the sucking disc can accurately position and suck the battery piece, so that the position of the battery piece is not easy to shift in the overturning process, and the production error caused by position deviation is reduced; buffer exists between the battery piece and the negative pressure hole, and the problem of'sucker marks' caused by direct contact of the battery piece is avoided, so that the surface quality of the battery piece is ensured.

A microfluidic chip for in vitro culture, comprising: a chamber, the chamber comprising a primary channel and at least one side channel adjacent thereto, the chamber having a bottom surface and a top surface, the chamber being configured as an open-top chamber having at least one aperture extending through the top surface and in fluid communication with the primary channel; and a separator disposed between the primary channel and the at least one side channel, the separator extending from the bottom surface of the chamber toward the top surface of the chamber; and optionally, an insert, the insert having at least one projection configured obstruct access to the aperture when the projection is placed into register with the one aperture. A method, comprising: contacting a solid tumor cell residing in the primary channel of a microfluidic chip and a sample cell perfused to the primary channel.

According to some example embodiments, a label pickup module may include a pad part including cells and suction holes penetrating through each cell from one surface of each of the cells contacting labels to the other surface; an adsorption flow path part on an upper portion of the pad part and an air movement passage formed therein, communicating with the suction holes; a rod parts having one side fixed to each of the cells and independently movable up and down; a body part on the other side of the rod parts, including rooms having a hollow shape configured to move while accommodating each of the rod parts, and having air holes configured to move air through each of the rooms; and an air blocking unit configured to open and close the air holes.

An electrical non-destructive real-time cell monitoring device according to an exemplary embodiment of the present invention comprises: a first electrode in contact with a cell; a second electrode provided at a position spaced apart from the first electrode; an impedance measurement unit connected to the first electrode and the second electrode; an LFP measurement unit connected to the first electrode and the second electrode; and a collected signal processing unit connected to the impedance measurement unit and the LFP measurement unit so as to receive and process measurement results, wherein the impedance measurement unit applies an alternating current to the second electrode so as to measure the impedance between the first electrode and the second electrode, the LFP measurement unit measures a local field potential between the first electrode and the second electrode and outputs a first digital signal, the impedance measurement unit and the LFP measurement unit operate simultaneously, and the collected signal processing unit processes a first digital signal so as to obtain a second digital signal.

In one aspect, a novel method that allows for evaluation of an RTK activity is provided. Provided is a method for evaluating an RTK activity, the method including: a step (A1) for determining diffusion dynamics A1 of the RTK by contacting a target substance with a cell that expresses a labeled RTK on a cell membrane, a step (B1) for determining diffusion dynamics B1 of the RTK by contacting the target substance and a ligand that activates the RTK with the cell that expresses the labeled RTK on a cell membrane, a step (C1) for calculating a ratio of the diffusion dynamics A1 of the RTK obtained at the step (A1) and the diffusion dynamics B1 of the RTK obtained at the step (B1), and a step (D1) for evaluating an effect of the target substance on an RTK activity by comparing the ratio of the diffusion dynamics obtained at the step (C1) with a threshold; and at the step (D1), when the ratio of the diffusion dynamics obtained at the step (C1) is equal to or greater than the threshold, it can indicate that the target substance has an effect on a molecular function of the RTK.

The invention relates to an electrical energy storage device (12) for a vehicle (10), comprising a housing (14) with a receiving space (24), at least one battery cell (30) and a cell contacting system (16) with at least one cell connector (34) for electrically contacting the battery cell (30), wherein the receiving space (24) is divided into a first receiving space (26) in which the at least one battery cell (30) is arranged and into a second receiving space (28) in which the cell contacting system (16) is arranged, wherein the first receiving space (26) is filled with a potting compound (36) by means of which the at least one battery cell (30) is connected to the housing (14), and wherein the second receiving space (28) is free of the potting compound (36).Furthermore, the invention relates to a method for manufacturing an electrical energy storage device (12) and to a vehicle comprising at least one such electrical energy storage device (12) and / or at least one electrical energy storage device (12) manufactured using such a method.

The invention provides a co-culture system for increasing the yield of endometrial stem cell exosomes and a method for increasing the yield of endometrial stem cell exosomes, firstly, fibroblasts are subjected to mitomycin C pretreatment, so that the cells are stagnated in G1, S and G2 stages of a cell cycle, meanwhile, RNA and protein synthesis continues to be carried out, and the endometrial stem cell exosomes are obtained; the fibroblasts are kept in a non-proliferative but metabolic active state; then, endometrial stem cells extracted from endometrial tissues in the proliferation period and fibroblasts are indirectly co-cultured through a Transwell chamber and are separated through a semi-permeable membrane, and stem cell differentiation caused by inter-cell contact reaction and fusion of the stem cells and somatic cells is eliminated; after co-culture, taking out the endometrial stem cells, putting the endometrial stem cells into a serum-free culture medium special for exosomes for separate culture, harvesting cell supernate, and purifying the exosomes; compared with the endometrial stem cells which are independently cultured in the whole process, the co-culture system disclosed by the invention has the advantages that the amplification speed of the endometrial stem cells and the exosome yield of unit quantity of cells are remarkably improved.

Battery pack and manufacturing method are provided. Battery pack includes cells contact system (CCS) assembly and cell assembly. CCS assembly includes injection molded member, vacuum-molded member, electrical connection plate, wiring harness. Injection molded member is connected to vacuum-molded member. Part of electrical connection plate is connected to injection molded member. Electrical connection plate is connected to vacuum-molded member. Wiring harness is connected to injection molded member, and further connected to electrical connection plate. Cell assembly includes battery cells electrically connected to electrical connection plate. Structural stiffness of injection molded member is greater than vacuum-molded member. Connection between injection molded member and vacuum-molded member reduces possibility of warping and deformation. Electrical connection plate mounted on vacuum-molded member is less prone to bending and deformation, and electrical connection plate is less prone to virtual electrical connection with cell. Electrical connection between electrical connector and cell has higher degree of operational reliability.

A substrate for an implanted microelectrode for implantation into tissue, such as a nerve, or in contact with a single cell for applying and / or recording electrical signals to and / or from the tissue or single cell is provided, the substrate comprising a first layer and a second layer deposited on at least a portion of a first surface of the first layer, the first layer and the second layer each extending in the x-direction and the y-direction, the first layer and the second layer stacked in the z-direction, (i) the first layer is based on a first mixture, the first mixture comprising a first component comprising at least one of: (a) a first photoinitiator, (b) a first monomer, a first oligomer, or a first polymer, the first monomer, (i) a first component, the first monomer or first oligomer or first copolymer comprising a first functional group, the first functional group being capable of being activated by a first photoinitiator such that the first component can be photopolymerized via the first functional group; and (ii) the second layer is based on a second mixture, the second mixture comprising: (c) a second photoinitiator; (d) a second component comprising a second monomer or second oligomer or second polymer, the second monomer or second oligomer or second copolymer comprising a first functional group, the first functional group being capable of being activated by a first photoinitiator such that the first component can be photopolymerized via the first functional group; and a second component, the second oligomer or second polymer being an acid and comprising a second functional group, the second functional group being capable of being activated by a second photoinitiator such that the second component can be linearly photopolymerized via the second functional group; (e) a base, the base being capable of neutralizing the second monomer or the second oligomer or the second polymer, thereby forming a salt; and (f) a third component comprising at least one of a third oligomer or third polymer, the third oligomer or third polymer comprising two functional groups, the two functional groups being a third functional group and a fourth functional group, each of the third functional group and the fourth functional group being capable of being activated by a second photoinitiator such that the third component can crosslink the second component via the third functional group and the fourth functional group; and wherein the swelling volume of the first layer is less than the swelling volume of the second layer.

The invention relates to a model for representing a cell module for an electrical energy storage device with a number of individual cells electrically connected in parallel by means of a cell contacting unit. According to the invention, each individual cell of the cell module is designed as a potentiometer (1) with an adjustable electrical resistance, wherein each potentiometer (1) has a cell housing (1.1) with electrically insulated electrical poles (P1, P2) arranged on a cell cover (1.2), wherein one electrical pole (P1) is formed by means of a threaded sleeve (2) rotatably mounted about its longitudinal axis, one end of which is electrically insulated from the cell cover (1.2).2) protrudes, a further electrical pole (P2) is formed by means of an electrically conductive conductor track (4) and a sliding contact (3) can be positioned by rotating the threaded sleeve (2) along the conductor track (4) and thus a running length of the conductor track (4) is specified or can be specified for setting an electrical resistance value.

The utility model provides an alarm and a battery compartment thereof, the battery compartment comprises a battery compartment shell and a pair of battery contact pieces, a battery mounting cavity is arranged in the battery compartment shell, two ends in the mounting cavity are provided with insert slots for mounting the battery contact pieces, the middle area of the battery contact pieces is provided with a hollow window, and the hollow window is connected with the battery contact pieces. A protruding cell panel is arranged in the hollowed-out window, the cell panel is integrally connected with the inner edge of the hollowed-out window, the edge of one side of the cell contact piece extends to form a printed board contact plate bent in an arc shape, the printed board contact plate is used for abutting against and making contact with a printed circuit board of the alarm under the limiting effect of the inserting piece inserting groove, and the cell contact piece is designed to be of an integral structure. The battery compartment is arranged in the battery compartment shell and is matched with a slot structure at a corresponding position in the battery compartment shell to realize stable matched installation, good contact with a battery electrode is ensured through a raised battery panel at one side, and the stability of contact and conduction with a printed circuit board is ensured through direct contact and conduction with the printed circuit board in the alarm through a printed board touch panel arranged at the other end of the battery compartment shell.