186 results about "Cell contact" patented technology

The utility model relates to the field of batteries, and discloses a collector plate and a battery, the collector plate comprises a plate body, first protrusions, second protrusions and third protrusions, the plurality of first protrusions are uniformly arranged on the plate body at intervals, liquid injection ports are formed between the adjacent first protrusions, the liquid injection ports are formed in the plate body in a penetrating manner, and the second protrusions are arranged on the plate body. The second protrusions are arranged at the ends, facing the center of the disc body, of the first protrusions, and the third protrusions are arranged at the ends, away from the center of the disc body, of the first protrusions. The first protrusions are arranged on the disc body, the second protrusions and the third protrusions are arranged at the two ends of the first protrusions respectively, the first protrusions, the second protrusions and the third protrusions form the bosses, and the bosses can make full contact with the flattened tabs and can flatten the tilted tabs again, so that the tabs make full contact with the tabs, and the tab flattening efficiency is improved. And short circuit caused by poor cell contact is prevented.

A non-volatile memory device comprises a substrate, a mold structure that includes gate electrodes stacked on the substrate and mold insulating layers alternately stacked with the gate electrodes, a cell contact on the substrate, wherein the cell contact is electrically connected to a selection gate electrode of the gate electrodes and is not electrically connected to a non-selection gate electrode of the gate electrodes, an insulating ring on the substrate, wherein the insulating ring is between the non-selection gate electrode and a sidewall of the cell contact and is in contact with the non-selection gate electrode, and a high dielectric constant layer between respective ones of the gate electrodes and the mold insulating layers, wherein the insulating ring includes a first portion that overlaps the high dielectric constant layer in a vertical direction, and a second portion that does not overlap the high dielectric constant layer in the vertical direction.

The present invention relates to reagent-coated cover slips and methods of using them to carry out one or more reactions. The present invention provides methods using reagent-coated cover slips to carry out a test on a carrier slide. The present invention provides methods where sample cells are immobilized on a carrier slide and a test is carried on the carrier slide. The present methods carry out one or more chemical reactions in the embedded sample cells on a carrier slide by contacting reagent-coated cover slips with sample cells immobilized on the carrier slide to result in a reaction product on the carrier slide.

According to some example embodiments, a label pickup module may include a pad part including cells and suction holes penetrating through each cell from one surface of each of the cells contacting labels to the other surface; an adsorption flow path part on an upper portion of the pad part and an air movement passage formed therein, communicating with the suction holes; a rod parts having one side fixed to each of the cells and independently movable up and down; a body part on the other side of the rod parts, including rooms having a hollow shape configured to move while accommodating each of the rod parts, and having air holes configured to move air through each of the rooms; and an air blocking unit configured to open and close the air holes.

An electrical non-destructive real-time cell monitoring device according to an exemplary embodiment of the present invention comprises: a first electrode in contact with a cell; a second electrode provided at a position spaced apart from the first electrode; an impedance measurement unit connected to the first electrode and the second electrode; an LFP measurement unit connected to the first electrode and the second electrode; and a collected signal processing unit connected to the impedance measurement unit and the LFP measurement unit so as to receive and process measurement results, wherein the impedance measurement unit applies an alternating current to the second electrode so as to measure the impedance between the first electrode and the second electrode, the LFP measurement unit measures a local field potential between the first electrode and the second electrode and outputs a first digital signal, the impedance measurement unit and the LFP measurement unit operate simultaneously, and the collected signal processing unit processes a first digital signal so as to obtain a second digital signal.

In one aspect, a novel method that allows for evaluation of an RTK activity is provided. Provided is a method for evaluating an RTK activity, the method including: a step (A1) for determining diffusion dynamics A1 of the RTK by contacting a target substance with a cell that expresses a labeled RTK on a cell membrane, a step (B1) for determining diffusion dynamics B1 of the RTK by contacting the target substance and a ligand that activates the RTK with the cell that expresses the labeled RTK on a cell membrane, a step (C1) for calculating a ratio of the diffusion dynamics A1 of the RTK obtained at the step (A1) and the diffusion dynamics B1 of the RTK obtained at the step (B1), and a step (D1) for evaluating an effect of the target substance on an RTK activity by comparing the ratio of the diffusion dynamics obtained at the step (C1) with a threshold; and at the step (D1), when the ratio of the diffusion dynamics obtained at the step (C1) is equal to or greater than the threshold, it can indicate that the target substance has an effect on a molecular function of the RTK.

The invention relates to an electrical energy storage device (12) for a vehicle (10), comprising a housing (14) with a receiving space (24), at least one battery cell (30) and a cell contacting system (16) with at least one cell connector (34) for electrically contacting the battery cell (30), wherein the receiving space (24) is divided into a first receiving space (26) in which the at least one battery cell (30) is arranged and into a second receiving space (28) in which the cell contacting system (16) is arranged, wherein the first receiving space (26) is filled with a potting compound (36) by means of which the at least one battery cell (30) is connected to the housing (14), and wherein the second receiving space (28) is free of the potting compound (36).Furthermore, the invention relates to a method for manufacturing an electrical energy storage device (12) and to a vehicle comprising at least one such electrical energy storage device (12) and / or at least one electrical energy storage device (12) manufactured using such a method.

The invention relates to a model for representing a cell module for an electrical energy storage device with a number of individual cells electrically connected in parallel by means of a cell contacting unit. According to the invention, each individual cell of the cell module is designed as a potentiometer (1) with an adjustable electrical resistance, wherein each potentiometer (1) has a cell housing (1.1) with electrically insulated electrical poles (P1, P2) arranged on a cell cover (1.2), wherein one electrical pole (P1) is formed by means of a threaded sleeve (2) rotatably mounted about its longitudinal axis, one end of which is electrically insulated from the cell cover (1.2).2) protrudes, a further electrical pole (P2) is formed by means of an electrically conductive conductor track (4) and a sliding contact (3) can be positioned by rotating the threaded sleeve (2) along the conductor track (4) and thus a running length of the conductor track (4) is specified or can be specified for setting an electrical resistance value.

An electrode unit for performing electroporation of a biological cell is provided, including at least one electrode which can contact a cell. A stimulation unit and an impedance measurement device are connected to the cell, respectively to provide signals to provide cell electroporation and to measure the impedance of the electrode in contact with the cell. Further, a memory stores a predetermined value of an impedance parameter of the biological cell, and it is arranged to be readable by a comparing element. The comparing element is configured to compare the value stored in the memory with a value measured with the impedance measurement device, and to produce an adjustment signal to the stimulation unit, forming a feedback loop. The unit is further configured to apply a further electrical signal for providing electroporation of the cell upon receiving the adjustment signal from the comparing element.

A semiconductor device can include a memory region and a peripheral region. The memory region can include cell vertical active patterns, cell gate electrodes, cell upper source / drain patterns, cell contact plugs, cell separation patterns, and data storage structures on the cell contact plugs and the cell separation patterns. The peripheral region can include peripheral vertical active patterns, peripheral gate electrodes having side surfaces facing side surfaces of the peripheral vertical active patterns, and peripheral upper source / drain patterns and peripheral upper interconnects on the peripheral vertical active patterns. Each of the cell upper source / drain patterns can contact a corresponding one of the cell vertical active patterns. The peripheral upper source / drain patterns can include a first peripheral upper source / drain pattern, and the first peripheral upper source / drain pattern can contact a first peripheral vertical active pattern and a second peripheral vertical active pattern among the peripheral vertical active patterns.

A variety of applications can include an apparatus having a memory device, where the memory device includes a digit line coupled to a access transistor of a memory device. The digit line can be at least partially buried below a top surface of substrate cell contacts to the access transistor. The top surface of the substrate cell contacts can be located at the surface of the substrate. The digit line can be formed in a separation of cell contacts first formation process flow or a digit line first formation process.

The disclosure relates to a device for detecting an impairment of a cell contacting system of a cell unit of an electrical energy store. The device is configured to determine a temporal progression of the voltage at the cell unit during a charging process or a discharging process of the energy store and to detect an impairment of the cell contacting system of the cell unit based on the temporal progression of the voltage at the cell unit.

The invention relates to a device for detecting a damage to a cell contact system of a cell unit of an electrical energy store. The device is designed to determine a time curve of the voltage across the cell unit during a charging or discharging process of the energy store, and to detect a damage to the cell contact system of the cell unit on the basis of the time curve of the voltage across the cell unit.

A method of manufacturing a semiconductor device is provided, including: providing a substrate, including an unit area and a peripheral area; forming a cell contact, a bit line structure and a spacer on the unit area, in which the spacer separates the cell contact and the bit line structure, forming a doped polysilicon layer on the cell contact, thereby forming a cell contact structure including the doped polysilicon layer and the cell contact, in which the doped polysilicon layer is doped with a semiconductor type ion; performing a first cleaning treatment on the cell contact structure by using water; and performing a second cleaning treatment on the cell contact structure by using diluted hydrofluoric acid or the water.

A biocompatible membrane composite including a cell impermeable layer and a mitigation layer is provided. The cell impermeable layer is impervious to vascular ingrowth and prevents cellular contact from the host. Additionally, the mitigation layer includes solid features. In at least one embodiment, mitigation layer has therein bonded solid features. In some embodiments, the cell impermeable layer and the mitigation layer are intimately bonded or otherwise connected to each other to form a composite layer having a tight / open structure. A reinforcing component may optionally be positioned external to or within the biocompatible membrane composite to provide support to and prevent distortion. The biocompatible membrane composite may be used in or to form a device for encapsulating biological entities, including, but not limited to, pancreatic lineage type cells such as pancreatic progenitors.

The present application discloses a semiconductor device and a method for fabricating the semiconductor device. The semiconductor device includes a substrate; a drain positioned in the substrate; a top dielectric layer positioned on the substrate; a cell contact structure including a cell contact bottom conductive layer positioned in the top dielectric layer and on the drain, a cell contact top conductive layer positioned in the top dielectric layer and on the cell contact bottom conductive layer, and a cell contact top sealing layer positioned in the top dielectric layer, on the cell contact bottom conductive layer, and surrounding the cell contact top conductive layer; a word line structure positioned in the drain and having a word line capping layer, wherein the word line capping layer has a tapered cross-section profile; and first air gap positioned in the top dielectric layer and surrounding the cell contact bottom conductive layer.

An apparatus comprising a memory array comprising word lines, bit lines, and memory cells, one or more of the memory cells coupled to an associated word line and an associated bit line and comprising active areas and shallow trench isolation (STI) structures adjacent to a base material. The word lines are in the active areas and STI structures and bit line structures are adjacent to the active areas and the STI structures and oriented perpendicular to the word lines. The bit line structures comprise bit lines and bit contacts. Cell contact structures are laterally adjacent to the bit line structures and comprise cell contacts comprising an epitaxial semiconductive material. One or more of the bit contacts and the epitaxial semiconductive material comprise a doped epitaxial silicon material, the doped epitaxial silicon material exhibiting a relatively greater dopant concentration in a [110] crystal orientation than in a [100] or [111] crystal orientation. Methods of forming the apparatus are also disclosed.

The invention relates to a microfluidic device. Said device has at least one magnetic marker, which is designed to bind to surface proteins of cells (30, 31), at least one mixing region, which is designed to bring the at least one magnetic marker into contact with the cells (30, 31), and at least one separating region (14), into which the cells (30, 31) can be introduced and which has at least one magnet (15), preferably on an upper side (16). A method for separating cells by means of the microfluidic device comprises bringing cells (30, 31) into contact with at least one magnetic marker in the mixing region, sedimenting the cells (30, 31) in the separating region (14), applying a magnetic field in the separating region (14), and discharging cells (31) marked with the marker from the separating region by means of a fluid flow (61).

Storage cell arrangement (18) for storing electrical energy comprising at least one storage cell (28), preferably a plurality of storage cells (28), such as a battery or accumulator, with a cell shell (30) and with cell contacts (32) which can be contacted from outside the cell shell (30) in order to connect the storage cell (28) electrically to an electrical load or a voltage source, the storage cell arrangement (18) further comprising an arrangement housing (20) surrounding the storage cell (28) with a fluid inlet (48) and a fluid outlet (50) in order to introduce a cooling fluid into the arrangement housing (20) and to discharge it again, wherein at least sectionally between the arrangement housing (20) and the at least one storage cell (28) a fluid flow space (46) is provided, which forms at least part of the flow path of the cooling fluid between the fluid inlet (48) and the fluid outlet (50),characterized in that the cell shell (30) is fluid-tight and the storage cell (28) including its cell contacts (32) is completely enclosed by the arrangement housing (20) and that the fluid flow space (46) is a gap space (46) between an outer wall region of the cell shell (30) and an inner wall region (42) of the arrangement housing (20), wherein the gap height in a section closer to the fluid supply line (48) is greater than in a section closer to the fluid outlet (50) of the flow path of the cooling fluid located inside the arrangement housing (20).

An electrical energy storage device is described which comprises a housing. The energy storage device further comprises a first storage cell and a second storage cell, which are arranged next to one another in the housing, such that an intermediate space filled with a filling compound is formed between the first storage cell and the second storage cell. The energy storage device further comprises a cell contacting system which electrically connects a contact point of the first storage cell to a contact point of the second storage cell via a connecting line. In addition, the energy storage device comprises a separating element which is designed to interrupt the connecting line when thermal energy acts on the separating element, and a separating element protector which encloses the separating element, wherein the separating element protector comprises a protective material which has a higher melting point than the filling compound.

Provided are a chemokine CXCL12 fusion protein and a use thereof. The chemokine CXCL12 fusion protein comprises the chemokine CXCL12 and an antibody against a tumor-associated antigen. The chemokine CXCL12 and the antibody against the tumor-associated antigen are directly fused or fused by means of a linker. On the one hand, the provided chemokine CXCL12 fusion protein can promote T cell infiltration and improve targeting. On the other hand, T cell killing signals are highly dependent on target cells, and T cells generate immune signals to kill the target cells only upon coming into contact with the target cells under the mediation of the fusion protein, thereby reducing toxic side effects.

A semiconductor device includes a memory region and a peripheral region. The memory region includes a cell vertical active pattern; a cell upper source / drain pattern and a cell contact plug sequentially stacked on the cell vertical active pattern; and a cell isolation pattern on side surfaces of the cell upper source / drain pattern and the cell contact plug. The peripheral region includes a peripheral vertical active pattern; a peripheral upper source / drain pattern and a peripheral contact plug sequentially stacked on the peripheral vertical active pattern; a peripheral isolation pattern on side surfaces of the peripheral upper source / drain pattern and the peripheral contact plug; and an upper wiring on the peripheral contact plug and the peripheral isolation pattern. The cell upper source / drain pattern includes a first cell upper source / drain pattern and a second cell upper source / drain pattern stacked in order.

To provide a surface structure for a cell culture substrate that exhibits high cell adhesiveness, and a cell culture chip.SOLUTION: A surface structure for a cell culture substrate is a surface on which cells are cultured, and the surface includes, at least in regions where the cells come into contact, recesses that allow biomolecules involved in cell adhesion to penetrate. The surface structure of the cell culture substrate is also a surface on which cells are cultured, and the surface includes, at least in regions where the cells come into contact, a plurality of protrusions that define valleys between the protrusions, the valleys being capable of receiving biomolecules involved in adhesion between the cells and the surface.SELECTED DRAWING: Figure 1

The invention is a method for training a system adapted for classifying biosensor signal corresponding to cell, wherein o the system comprises a machine learning-based classification module, and o sensor-surface time-dependent biosensor signals (26) obtained by contacting a sample with cell(s) (32) with functionalised surface of an optical biosensor (24) for detecting refractive index change, representing activation kinetics and defined on pixels (30) of the biosensor (24) are applied, the method comprising, for the sensor-surface time-dependent biosensor signals (26), - a training time-dependent biosensor signal portion comprising a pixel of the given sensor-surface time-dependent biosensor signal (26) corresponding to a cell (32) is determined, and - the classification module is trained with the training time-dependent biosensor signal portion, classification of activation kinetics of the cell (32) is specified. Furthermore, the invention is a system and an evaluation method for classifying biosensor signal corresponding to cell.

The application relates to the photovoltaic technology field and discloses a solar cell, a preparation method thereof and a photovoltaic module. The solar cell comprises a silicon substrate with a first surface and a second surface arranged oppositely; a first intrinsic amorphous silicon layer located on at least a partial region of the first surface of the silicon substrate; a first doped microcrystalline silicon layer located on a side of the first intrinsic amorphous silicon layer away from the silicon substrate; a first doped amorphous silicon layer located on a side of the first doped microcrystalline silicon layer away from the first intrinsic amorphous silicon layer, wherein the first doped amorphous silicon layer and the first doped microcrystalline silicon layer have the same doping type; and a first transparent conductive layer located on a side of the first doped amorphous silicon layer away from the first doped microcrystalline silicon layer. The application can improve the cell contact performance, reduce the cell series resistance and thus improve the cell conversion efficiency.

A cell culture method, using a cell culture medium, excluding human embryonic stem cells, the method comprising: (i) contacting the culture medium with at least one cell; (ii) placing the culture medium in a chamber (40) containing a culture medium; the method being characterized in that the medium comprises particles sensitive to a magnetic field, and that the medium has, along a longitudinal axis, a dimension greater than the dimensions along another axis, the larger dimension forming a length of the medium, the method comprising: (iii) applying a magnetic field in the chamber, the magnetic field forming field lines extending through the chamber; (iv) following (iii) suspending each culture medium in a culture medium contained in a chamber. Figure 6

Disclosed is a battery pack, including a cell contact system, CCS, assembly; a battery box, in which the CCS assembly is mounted and fixed in the battery box; and a sealant component, in which the sealant component is provided between the battery box and the CCS assembly, and the sealant component is extended along a peripheral direction of the CCS assembly to seal an assembly clearance between the CCS assembly and the battery box.

System (1000) comprising a component (10) and a coating device (100) for applying a coating medium to the component (10), the coating device (100) comprising a detection device (102) configured to detect at least one geometric property (h) of the component (10), and at least one coating nozzle (104) movable relative to the component (10), configured to coat only selective areas of a component surface of the component (10) with the coating medium depending on the at least one geometric property (h) and depending on at least one predetermined, component-dependent coating criterion based on the at least one geometric property (h), wherein the component (10) comprises a cell cluster (16) with several energy storage cells (18), a cell contacting device (20) and a summation current connector (21), wherein the coating device (100) is configured toonly the cell shoulder areas (22) of the energy storage cells (18) are coated with the coating medium, wherein after coating the cell contacting device (20) and the summation current connector (21) are free of coating medium.

The application discloses a biocontrol pantoea agglomerans KBA33 for inhibiting botryosphaeria dothidea and application thereof. The strain KBA33 disclosed by the application can effectively inhibit botryosphaeria dothidea at 16 DEG C and 28 DEG C, and can inhibit botryosphaeria dothidea through cell-cell contact.

The object of the present invention is to provide a method for analyzing the disorder of collagen in living organisms. [Solution] The above problem can be solved by a screening method for cellular senescence-related substances, which includes the step of contacting a candidate substance with cells expressing procollagen C-proteinase, procollagen C-proteinase enhancer, procollagen C-proteinase-cleaved protein, procollagen N-proteinase, procollagen N-proteinase activator, or procollagen N-proteinase-cleaved protein of the present invention.