107 results about "Cell contact" patented technology

A non-volatile memory device comprises a substrate, a mold structure that includes gate electrodes stacked on the substrate and mold insulating layers alternately stacked with the gate electrodes, a cell contact on the substrate, wherein the cell contact is electrically connected to a selection gate electrode of the gate electrodes and is not electrically connected to a non-selection gate electrode of the gate electrodes, an insulating ring on the substrate, wherein the insulating ring is between the non-selection gate electrode and a sidewall of the cell contact and is in contact with the non-selection gate electrode, and a high dielectric constant layer between respective ones of the gate electrodes and the mold insulating layers, wherein the insulating ring includes a first portion that overlaps the high dielectric constant layer in a vertical direction, and a second portion that does not overlap the high dielectric constant layer in the vertical direction.

The present invention relates to reagent-coated cover slips and methods of using them to carry out one or more reactions. The present invention provides methods using reagent-coated cover slips to carry out a test on a carrier slide. The present invention provides methods where sample cells are immobilized on a carrier slide and a test is carried on the carrier slide. The present methods carry out one or more chemical reactions in the embedded sample cells on a carrier slide by contacting reagent-coated cover slips with sample cells immobilized on the carrier slide to result in a reaction product on the carrier slide.

According to some example embodiments, a label pickup module may include a pad part including cells and suction holes penetrating through each cell from one surface of each of the cells contacting labels to the other surface; an adsorption flow path part on an upper portion of the pad part and an air movement passage formed therein, communicating with the suction holes; a rod parts having one side fixed to each of the cells and independently movable up and down; a body part on the other side of the rod parts, including rooms having a hollow shape configured to move while accommodating each of the rod parts, and having air holes configured to move air through each of the rooms; and an air blocking unit configured to open and close the air holes.

The invention relates to a model for representing a cell module for an electrical energy storage device with a number of individual cells electrically connected in parallel by means of a cell contacting unit. According to the invention, each individual cell of the cell module is designed as a potentiometer (1) with an adjustable electrical resistance, wherein each potentiometer (1) has a cell housing (1.1) with electrically insulated electrical poles (P1, P2) arranged on a cell cover (1.2), wherein one electrical pole (P1) is formed by means of a threaded sleeve (2) rotatably mounted about its longitudinal axis, one end of which is electrically insulated from the cell cover (1.2).2) protrudes, a further electrical pole (P2) is formed by means of an electrically conductive conductor track (4) and a sliding contact (3) can be positioned by rotating the threaded sleeve (2) along the conductor track (4) and thus a running length of the conductor track (4) is specified or can be specified for setting an electrical resistance value.

An electrode unit for performing electroporation of a biological cell is provided, including at least one electrode which can contact a cell. A stimulation unit and an impedance measurement device are connected to the cell, respectively to provide signals to provide cell electroporation and to measure the impedance of the electrode in contact with the cell. Further, a memory stores a predetermined value of an impedance parameter of the biological cell, and it is arranged to be readable by a comparing element. The comparing element is configured to compare the value stored in the memory with a value measured with the impedance measurement device, and to produce an adjustment signal to the stimulation unit, forming a feedback loop. The unit is further configured to apply a further electrical signal for providing electroporation of the cell upon receiving the adjustment signal from the comparing element.

A semiconductor device can include a memory region and a peripheral region. The memory region can include cell vertical active patterns, cell gate electrodes, cell upper source / drain patterns, cell contact plugs, cell separation patterns, and data storage structures on the cell contact plugs and the cell separation patterns. The peripheral region can include peripheral vertical active patterns, peripheral gate electrodes having side surfaces facing side surfaces of the peripheral vertical active patterns, and peripheral upper source / drain patterns and peripheral upper interconnects on the peripheral vertical active patterns. Each of the cell upper source / drain patterns can contact a corresponding one of the cell vertical active patterns. The peripheral upper source / drain patterns can include a first peripheral upper source / drain pattern, and the first peripheral upper source / drain pattern can contact a first peripheral vertical active pattern and a second peripheral vertical active pattern among the peripheral vertical active patterns.

A variety of applications can include an apparatus having a memory device, where the memory device includes a digit line coupled to a access transistor of a memory device. The digit line can be at least partially buried below a top surface of substrate cell contacts to the access transistor. The top surface of the substrate cell contacts can be located at the surface of the substrate. The digit line can be formed in a separation of cell contacts first formation process flow or a digit line first formation process.

A method of manufacturing a semiconductor device is provided, including: providing a substrate, including an unit area and a peripheral area; forming a cell contact, a bit line structure and a spacer on the unit area, in which the spacer separates the cell contact and the bit line structure, forming a doped polysilicon layer on the cell contact, thereby forming a cell contact structure including the doped polysilicon layer and the cell contact, in which the doped polysilicon layer is doped with a semiconductor type ion; performing a first cleaning treatment on the cell contact structure by using water; and performing a second cleaning treatment on the cell contact structure by using diluted hydrofluoric acid or the water.

An apparatus comprising a memory array comprising word lines, bit lines, and memory cells, one or more of the memory cells coupled to an associated word line and an associated bit line and comprising active areas and shallow trench isolation (STI) structures adjacent to a base material. The word lines are in the active areas and STI structures and bit line structures are adjacent to the active areas and the STI structures and oriented perpendicular to the word lines. The bit line structures comprise bit lines and bit contacts. Cell contact structures are laterally adjacent to the bit line structures and comprise cell contacts comprising an epitaxial semiconductive material. One or more of the bit contacts and the epitaxial semiconductive material comprise a doped epitaxial silicon material, the doped epitaxial silicon material exhibiting a relatively greater dopant concentration in a [110] crystal orientation than in a [100] or [111] crystal orientation. Methods of forming the apparatus are also disclosed.

Storage cell arrangement (18) for storing electrical energy comprising at least one storage cell (28), preferably a plurality of storage cells (28), such as a battery or accumulator, with a cell shell (30) and with cell contacts (32) which can be contacted from outside the cell shell (30) in order to connect the storage cell (28) electrically to an electrical load or a voltage source, the storage cell arrangement (18) further comprising an arrangement housing (20) surrounding the storage cell (28) with a fluid inlet (48) and a fluid outlet (50) in order to introduce a cooling fluid into the arrangement housing (20) and to discharge it again, wherein at least sectionally between the arrangement housing (20) and the at least one storage cell (28) a fluid flow space (46) is provided, which forms at least part of the flow path of the cooling fluid between the fluid inlet (48) and the fluid outlet (50),characterized in that the cell shell (30) is fluid-tight and the storage cell (28) including its cell contacts (32) is completely enclosed by the arrangement housing (20) and that the fluid flow space (46) is a gap space (46) between an outer wall region of the cell shell (30) and an inner wall region (42) of the arrangement housing (20), wherein the gap height in a section closer to the fluid supply line (48) is greater than in a section closer to the fluid outlet (50) of the flow path of the cooling fluid located inside the arrangement housing (20).

Provided are a chemokine CXCL12 fusion protein and a use thereof. The chemokine CXCL12 fusion protein comprises the chemokine CXCL12 and an antibody against a tumor-associated antigen. The chemokine CXCL12 and the antibody against the tumor-associated antigen are directly fused or fused by means of a linker. On the one hand, the provided chemokine CXCL12 fusion protein can promote T cell infiltration and improve targeting. On the other hand, T cell killing signals are highly dependent on target cells, and T cells generate immune signals to kill the target cells only upon coming into contact with the target cells under the mediation of the fusion protein, thereby reducing toxic side effects.

A cell culture method, using a cell culture medium, excluding human embryonic stem cells, the method comprising: (i) contacting the culture medium with at least one cell; (ii) placing the culture medium in a chamber (40) containing a culture medium; the method being characterized in that the medium comprises particles sensitive to a magnetic field, and that the medium has, along a longitudinal axis, a dimension greater than the dimensions along another axis, the larger dimension forming a length of the medium, the method comprising: (iii) applying a magnetic field in the chamber, the magnetic field forming field lines extending through the chamber; (iv) following (iii) suspending each culture medium in a culture medium contained in a chamber. Figure 6

System (1000) comprising a component (10) and a coating device (100) for applying a coating medium to the component (10), the coating device (100) comprising a detection device (102) configured to detect at least one geometric property (h) of the component (10), and at least one coating nozzle (104) movable relative to the component (10), configured to coat only selective areas of a component surface of the component (10) with the coating medium depending on the at least one geometric property (h) and depending on at least one predetermined, component-dependent coating criterion based on the at least one geometric property (h), wherein the component (10) comprises a cell cluster (16) with several energy storage cells (18), a cell contacting device (20) and a summation current connector (21), wherein the coating device (100) is configured toonly the cell shoulder areas (22) of the energy storage cells (18) are coated with the coating medium, wherein after coating the cell contacting device (20) and the summation current connector (21) are free of coating medium.

The application discloses a biocontrol pantoea agglomerans KBA33 for inhibiting botryosphaeria dothidea and application thereof. The strain KBA33 disclosed by the application can effectively inhibit botryosphaeria dothidea at 16 DEG C and 28 DEG C, and can inhibit botryosphaeria dothidea through cell-cell contact.

The object of the present invention is to provide a method for analyzing the disorder of collagen in living organisms. [Solution] The above problem can be solved by a screening method for cellular senescence-related substances, which includes the step of contacting a candidate substance with cells expressing procollagen C-proteinase, procollagen C-proteinase enhancer, procollagen C-proteinase-cleaved protein, procollagen N-proteinase, procollagen N-proteinase activator, or procollagen N-proteinase-cleaved protein of the present invention.

The invention relates to a cell contacting system by means of which elementary storage cells are electrically connected to one another in series and / or parallel circuits in order to form a battery module and / or pack, and at least one electrical contact for a pole of an elementary storage cell is in the form of an electrical fuse element in the cell contacting system. The aim of the invention is to improve a cell contacting system comprising electrical fuse elements. This is achieved in that the cell contacting system (1) is provided with fuse elements (6, 8) for each elementary storage cell (3) as protection against a low-resistance short circuit and as protection against a medium-resistance short circuit.

The invention relates to a method for manufacturing a battery cell (10) for a vehicle battery, wherein the battery cell (10) comprises an electrochemical energy storage device (14) configured for storing electrical energy, and a battery cell housing (16) enclosing the electrochemical energy storage device (14), which comprises a can (18) and a lid (20), wherein in the method the electrochemical energy storage device (14) is received in a receiving space (22) bounded by the can (18) and the receiving space (22) is closed by connecting the can (18) to the lid (20), wherein two contact lines (24) are attached to the battery cell housing (16) before connecting the lid (20) to the can (18), one of which is electrically contacted with a positive terminal (28) of the battery cell housing (16) and the other with a negative terminal (30) of the battery cell housing (16).the battery cell (10) can be connected to a cell contacting system (12) of the vehicle battery via the contact lines (24).

In cell culture, the microcarriers are brought into contact with cells adhering to the bottom surface of a first culture substrate having a bottom surface treated for cell adhesion.

This invention relates to a battery pack and / or battery module based on cylindrical battery cells, wherein the battery cells are electrically connected to each other in series and parallel via a cell contact system, wherein the two electrodes of each battery cell (2) are in contact on the unoccupied top side (7) of the battery module or battery pack (1), and relates to a battery system thus constituted, which acts as a device for supplying and storing electrical energy. In order to provide a battery pack and / or battery module that can more easily and quickly achieve solutions for specific customers and / or applications without completely or at least largely redeveloping or redesigning the battery system thus constituted and without changing safety, it is proposed that a battery module and / or battery pack (1) consisting of one or more base battery packs having a fixed number of battery cells (2) is arranged in a spatially predefined manner and in contact with a base cell contact system (4a), wherein the electrical characteristics of the battery module and / or battery pack (1) are achieved by connecting several base cell contact systems (4a) of several base battery packs.

Methods of regulating expression of a target gene in a cell are provided. Aspects of the methods contacting the cell with a compound having a first moiety covalently linked to a second moiety, wherein: (i) the first moiety exhibits specific binding to a first endogenous protein; (ii) the second moiety exhibits specific binding to a second endogenous protein distinct from the first endogenous protein; and (iii) upon contacting the cell, the first endogenous protein and the second endogenous protein are spatially complexed to each other via the compound to yield a gain-of-function in the cell and thereby activate a process not normally controlled by either of the first and second endogenous proteins. Embodiments of the methods provide one or more beneficial features, including but not limited to: utilization of less than about 50% of an amount of the second endogenous protein present in the cell; mediation of the gain-of-function with an EC50 of less than about 1 micromolar; modulation of expression of the target gene in less than or equal to about 16 hours; etc. Also provided are compositions that find use in practicing methods of the disclosure.

The invention discloses a method for separating cochlea related cells in situ based on a patch clamp system. The method comprises the following steps: contacting an electrode with a target single cell under a microscope, and carrying out in-situ grabbing on the target single cell through negative pressure adsorption; the target single cell and surrounding cells are kept in a connection state before in-situ grabbing; before the electrode approaches the target single cell, positive pressure is continuously applied, and when the electrode is in contact with the surface of the target single cell, the positive pressure is instantly stopped and switched to negative pressure. According to the method provided by the invention, high-quality cochlea related cells can be obtained in situ for deep sequencing analysis, and the method can be used for basic research and accurate diagnosis and treatment of clinical hearing impairment, and has a good application prospect.

The invention relates to the technical field of biomedical engineering, in particular to Pickering emulsion as well as a preparation method and application thereof. According to the invention, lentinan is selected as an immune agonist and is combined with PLGA, so that the immunocompetence of PLGA as an adjuvant is enhanced; the PLGA-coated lentinan can prevent the antigen from being directly exposed in an organic solvent to influence the activity of the antigen; compared with PLGA nanoparticles, the Pickering emulsion has a larger specific surface area and can adsorb more antigens; the Pickering emulsion has good fluidity and can increase the interaction between the PLGA nanoparticles and cell membranes, when the PLGA nanoparticles are in contact with antigen presenting cells (APCs), a large number of antigens are absorbed by the APCs, and the activated APCs can carry a large number of nanoparticles to enter lymph nodes, so that the Pickering emulsion has good lymph node targeting property. Upon uptake of a large number of antigens, the immune cells induce strong cellular or humoral immune responses in various ways.

The invention relates to a hybrid cell holding structure for a battery system for a motor vehicle. The hybrid cell holding structure comprises an upper cell holding structure, a lower cell holding structure, and at least one spacer, wherein the upper cell holding structure and the lower cell holding structure are arranged parallel to each other and spaced apart. At least two accumulators are arranged between the upper cell holding structure and the lower cell holding structure, wherein the at least two accumulators penetrate the spacer, which is arranged between the upper cell holding structure and the lower cell holding structure, at an angle.The at least two accumulators each comprise a first end face with a first contact area and a second end face with a second contact area, wherein the upper cell holding structure for the at least two accumulators each comprises a through-opening, wherein the through-openings are designed for contacting with a cell contacting system of the first contact area and the second contact area of ​​the at least two accumulators, and the lower cell holding structure for the at least two accumulators each comprises a through-opening, wherein the through-openings are designed for contacting with a cell contacting system of the first contact area and the second contact area of ​​the at least two accumulators.

The present invention relates to a cell contacting system in which elementary storage cells are electrically interconnected in series and / or parallel circuits to form a battery module and / or pack, and in which at least one electrical contact to a pole of an elementary storage cell is designed as an electrical safety element. To improve a cell contacting system comprising electrical safety elements, it is proposed that in the cell contacting system (1) safety elements (6, 8) are provided for each elementary storage cell (3) as protection against a low-resistance short circuit and as protection against a medium-resistance short circuit.

The invention relates to a cell contacting system (1), by means of which elementary storage cells (2) are electrically connected to each other in series and / or parallel circuits in order to form a battery module or pack, and to a battery module or pack, which is provided for constructing a high-voltage battery system as a device for outputting and storing electrical energy while protecting against excessive current flows. The aim of the invention is to improve a cell contacting system (1). This is achieved in that the fuse element (5) is well thermally insulated from the surroundings.

This invention provides a method for manufacturing a semiconductor structure. A substrate is provided. A bitline conductive layer is formed on the substrate. A bitline dielectric layer is formed on the bitline conductive layer. A first hard mask layer and a second hard mask layer are formed on the bitline dielectric layer. A first trench is formed to define the bitline dielectric layer and the bitline conductive layer as a bitline structure, wherein the second hard mask layer on the bitline dielectric layer is removed, while the first hard mask layer on the bitline dielectric layer is retained. A sacrificial layer is formed within the first trench. The sacrificial layer is removed to form a second trench, and the first hard mask layer is removed to expose the top surface of the bitline dielectric layer. Cell contacts are formed within the second trench.

A semiconductor device includes a substrate including a source region and a drain region; a word line structure including a word line dielectric layer in the substrate, a word line conductive layer on the word line dielectric layer and within the substrate, and a word line capping layer on the word line conductive layer; a top thickening layer between the word line conductive layer and the word line capping layer, and between the word line dielectric layer and the word line capping layer; a bottom capping layer on the substrate and adjacent to the word line dielectric layer; a top capping layer covering the bottom capping layer and the word line structure; a bit line penetrating through the top and bottom capping layers and extending into the source region; and a cell contact penetrating through the top and bottom capping layers and extending into the drain region.

The present invention relates to a cell contacting system by which elementary storage cells are electrically interconnected in series and / or parallel circuits to form a battery module or pack, and to a battery module or pack which is provided for the construction of a high-voltage battery system as a device for supplying and storing electrical energy while being protected against excessive current flows. To improve a cell contacting system, it is proposed that the locking element (5) be well thermally insulated from the environment.

Methods, systems, and devices for a selective memory cell contact liner are described. A memory array may implement a protective liner within a memory cell structure including a cell contact for coupling memory storage material with an access device, a bit line associated with accessing the memory cell structure, and a bit line contact associated with activating the bit line. Forming the memory cell structure with the protective liner may include forming memory storage material, insulative material around the memory storage material, the bit line contact, the bit line, and the cavity. Then, a portion of the memory storage material may be replaced with a material associated with impeding deposition of the protective liner. The protective liner may be deposited within the cavity such that the bit line contact is covered by the protective liner but the memory storage material is not covered by the protective liner.