Anti-asthmatic and anti-inflammatory medicament and preparation method and application thereof

A drug and anti-asthma technology, applied in the direction of drug combination, medical formula, plant raw materials, etc., can solve the problems of not meeting clinical needs, not being able to treat both symptoms and root causes, and adverse reactions, achieving good therapeutic effect, no toxic side effects, increasing drug effective effect

Inactive Publication Date: 2013-10-30
唐本芬
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, Western medicine often uses antibiotics combined with cough and asthma drugs to treat such diseases, mainly treating the symptoms and temporarily relieving the disease, but it cannot achieve the goal of treating both symptoms and root causes, and repeated use of antibiotics can easily lead to many adverse reactions.
There are many varieties and quantities of traditional Chinese medicines for the treatment of chronic bronchitis and bronchial asthma, but most of them are old varieties and imitation varieties, the effect is slow and not obvious, and cannot meet the clinical needs, and the products are also facing problems such as replacement

Method used

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  • Anti-asthmatic and anti-inflammatory medicament and preparation method and application thereof
  • Anti-asthmatic and anti-inflammatory medicament and preparation method and application thereof
  • Anti-asthmatic and anti-inflammatory medicament and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Example 1 Medicine of the present invention and preparation method thereof

[0029] Drug formula: Octopus 5 grams; Rock cabbage 5 grams; Iron chopsticks 1 gram; Wanzhangshen 5 grams;

[0030] Preparation method: Weigh the raw materials according to the above-mentioned amount, grind them into fine powder, sieve, mix evenly, pack into capsules, and sterilize to obtain capsules, and each capsule contains 0.32 grams of medicine.

[0031] implement pour 2 Medicine of the present invention and preparation method thereof

[0032] Drug formula: 7 grams of octopus; 7 grams of rock cabbage; 3 grams of iron chopsticks; 7 grams of ten thousand zhangshen; 3 grams of tiger palm;

[0033] Preparation method: Weigh the raw materials according to the above-mentioned amount, grind them into fine powder, sieve, mix evenly, pack into capsules, and sterilize to obtain capsules, and each capsule contains 0.32 grams of medicine.

[0034] implement pour 3 Medicine of the present inventi...

Embodiment 5

[0044] Example 5 Pharmacodynamic research on anti-inflammation, antibacterial and anti-asthma drug of the present invention

[0045] 1. Test drug

[0046] Pingchuan Xiaoyan powder: prepared in Example 3. Distilled water was used to prepare suspensions with four concentrations of 0.5% (g / ml), 1% (g / ml), 2% (g / ml) and 4% (g / ml). Among them, the suspension of 0.5% (g / ml) and 1% (g / ml) is given 0.4ml / kg by intragastric administration, and the dosage is 200mg / kg and 400mg / kg, which is equivalent to 7.4 times of the adult daily dose and 14.8 times.

[0047] Aspirin Tablets: Shenyang Keda Pharmaceutical Factory, made into a suspension of 0.5% (g / ml) concentration with distilled water for use, administered by intragastric administration of 0.4ml / kg, and the dose is 200mg / kg.

[0048] Aminophylline injection: Shanghai Xinyi Pharmaceutical Factory, diluted with normal saline to a 1% (V / V) solution for use.

[0049] 2. Experimental animals

[0050] Kunming white mice, half male an...

Embodiment 6

[0072] Example 6 The clinical curative effect of medicine treatment emphysema of the present invention

[0073] 1. Case selection and diagnostic criteria:

[0074] 1. Case selection

[0075] 674 cases were treated, including 375 males and 299 females, the oldest was 78 years old, the youngest was 13 years old, and the average age was 41 years old.

[0076] 2. Diagnostic criteria: Western medicine diagnostic criteria, with typical symptoms of emphysema such as shortness of breath, dyspnea, chest tightness, and other diseases that can cause the above symptoms.

[0077] 2. Treatment

[0078] Use the capsules prepared in Example 1, 2 capsules each time, 3 times a day. Those who can drink can take it better with wine. Every 20 days is a course of treatment, and each course of treatment can be separated by 1-2 days.

[0079] 3. Efficacy Judgment Criteria

[0080] 1. Clinical cure: shortness of breath, dyspnea, chest tightness, chest pain and other main symptoms basically disap...

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Abstract

The invention relates to an anti-asthmatic and anti-inflammatory medicament and a preparation method and application thereof. The anti-asthmatic and anti-inflammatory medicament is made from the following raw materials in parts by weight: 5 to 8 parts of Ardisia crenata, 5 to 7 parts of Bergenia purpurascens, 1 to 3 parts of Tibetan hellebore, 5 to 7 parts of Crepis phoenix, 1 to 3 parts of Anemone rivularis, 2 to 4 parts of Herba Epimedii, 2 to 4 parts of Gentiana rhodantha and 3 to 4 parts of Polygonum cuspidatum. The medicament has the effects of removing heat and toxic substances, moistening the lung, stopping cough, relieving asthma and tonifying the kidney-yang; and has a high effective rate and a stable long-term efficacy.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine and Miao medicine, and relates to an antiasthmatic and anti-inflammatory drug, a preparation method and application thereof. Background technique [0002] Chronic bronchitis and bronchial asthma belong to the category of "cough" and "asthma" in traditional Chinese medicine. They are common and frequently-occurring diseases, and the incidence rate of middle-aged and elderly people is extremely high. According to statistics, it accounts for more than 75% of the total number of middle-aged and elderly people. Emphysema is more common in middle-aged and elderly people over 40 years old, with a history of various respiratory diseases such as chronic bronchitis and bronchial asthma. At present, Western medicine often uses antibiotics combined with cough and asthma drugs to treat such diseases. It mainly treats the symptoms and can temporarily relieve the disease, but it cannot achieve the go...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/71A61P9/00A61P11/00A61P11/04A61P11/06A61P11/14
Inventor 唐本芬张庆
Owner 唐本芬
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