The present application relates to a kind of
quercetin and
ketotifen co-
assembly nanomedicine and its construction method and application, belong to
nanomedicine technical field;The construction method includes the following steps: S1,
quercetin and
ketotifen are dissolved in
organic solvent, and mixed uniformly;S2, remove
organic solvent, so that
quercetin and
ketotifen co-
assembly occurs, and forms co-
assembly solid;S3, to co-assembly
solid is added dispersion medium and is hydrated, and is treated by
ultrasonic dispersion, and the dispersion liquid of quercetin and ketotifen co-assembly
nanomedicine is obtained.The present application is creatively constructed as co-assembly nanomedicine without any exogenous carrier, not only simultaneously solves the technical problems of poor water-
solubility of quercetin and obvious central inhibition side effects of ketotifen, but also realizes the treatment goal of high efficiency,
low toxicity, synergistic anti-
asthma, with significant clinical conversion prospect and industrial application value.