6 results about "Anti asthmatic" patented technology

The invention relates to the technical field of aromatherapy products, in particular to a preparation method and application of a saussurea lappa extract, and the preparation method comprises the following steps: crushing saussurea lappa, ultrasonically extracting with an ethanol solution in a specific proportion, filtering, and concentrating under reduced pressure to obtain the extract. The extract can be used in solid aromatherapy, liquid aromatherapy, aromatherapy candles or perfume compositions. The obtained product provides an environment-friendly and safe fragrance selection by utilizing the natural wood medicine fragrance characteristic of the saussurea lappa, meanwhile, the inherent spasmolysis and anti-asthma effects of the saussurea lappa are reserved, the problems of high irritation and low safety of traditional synthetic aromatherapy are solved, and the application value of traditional Chinese medicinal materials in the fragrance field is expanded.

The present application relates to a kind of quercetin and ketotifen co-assembly nanomedicine and its construction method and application, belong to nanomedicine technical field;The construction method includes the following steps: S1, quercetin and ketotifen are dissolved in organic solvent, and mixed uniformly;S2, remove organic solvent, so that quercetin and ketotifen co-assembly occurs, and forms co-assembly solid;S3, to co-assembly solid is added dispersion medium and is hydrated, and is treated by ultrasonic dispersion, and the dispersion liquid of quercetin and ketotifen co-assembly nanomedicine is obtained.The present application is creatively constructed as co-assembly nanomedicine without any exogenous carrier, not only simultaneously solves the technical problems of poor water-solubility of quercetin and obvious central inhibition side effects of ketotifen, but also realizes the treatment goal of high efficiency, low toxicity, synergistic anti-asthma, with significant clinical conversion prospect and industrial application value.

The application provides an animal Bifidobacterium lactis subsp. and an application thereof for preventing and relieving allergic asthma symptoms. The animal Bifidobacterium lactis subsp. is named animal Bifidobacterium lactis subsp. HNU319, has been preserved in the Guangdong Microbial Culture Collection Center (GDMCC) on May 9, 2026, has a preservation number of GDMCC No: 68233, and is classified and named as Bifidobacterium animalis subsp. lactis. The strain exerts an anti-asthma effect through an 'entero-pulmonary axis' regulation network, has the advantages of high safety, clear mechanism and remarkable effect, can be used for developing functional food, microecological preparations or as an active ingredient for the prevention and adjuvant treatment of respiratory diseases, and has a broad industrialization prospect.

The application discloses a new water-soluble phenolic acid salviamarinic acid B extracted from radix salviae miltiorrhizae, adopts a C48 / 80 induced RBL-2H3 cell degranulation in vitro model to simulate the degranulation phenomenon of mast cells in vitro, and first separates and identifies a new water-soluble phenolic acid compound (salviamarinic acid B) from the ethyl acetate part of radix salviae miltiorrhizae, which can inhibit the release of beta-Hex, reduce the levels of mMCP-1, beta-MCT, HIS and LTC4, significantly improve the degranulation phenomenon of RBL-2H3 cells, has significant anti-asthma activity, and has significant social and economic benefits.

The invention provides application of a senecio scandens plant polysaccharide extract in preparation of a medicine for preventing and / or treating asthma, and belongs to the technical field of biological medicine manufacturing. The senecio scandens polysaccharide extract is extracted from senecio scandens by utilizing a water extraction and alcohol precipitation method. According to the invention, a rat asthma model is taken as an experimental subject, a pharmacodynamic evaluation experiment of the senecio scandens polysaccharide extract is carried out, and a result shows that NF-kappa B phosphorylation is prevented and release of inflammation-related cytokines is inhibited by inhibiting mRNA expression of a PI3K / AKT pathway and an MAPKs signal pathway and phosphorylation activation of related proteins, so that a Th1 / Th2 equilibrium state is adjusted, and the efficacy of the senecio scandens polysaccharide extract is improved. The airway inflammatory response and airway remodeling are inhibited, and the anti-asthma effect is achieved. The invention provides the application of the senecio scandens plant polysaccharide extract in preparation of the medicine for preventing and / or asthma, and a new way is provided for clinical treatment of asthma and medicine development.

The invention belongs to the field of medicinal plant development, and particularly relates to an anti-asthma inflammation traditional Chinese medicine extract as well as an extraction method and application thereof. Millettia specisoa champ is used as a raw material, and Millettia specisoa champ total flavonoids and Millettia specisoa champ total The two extracts are subjected to pharmacological experiments, and researches show that the beautiful millettia root extract containing the total flavonoids or the total polysaccharides can remarkably reduce the levels of Th2 inflammatory factors such as IL-4, IL-5, IL-9, IL-13 and GATA-3 in lung tissues, improve the levels of Th1 anti-inflammatory factors such as IFN-gamma, IL-12 and IL-27, regulate the proportion balance of Th1 / Th2 and inhibit airway inflammatory response; in addition, GATA-3 expression can be blocked, Th2 cell activation hyperfunction is inhibited, pathological characteristic change of asthma is relieved, and great development and utilization potential in asthma treatment is achieved.