44 results about "Senecio scandens" patented technology

The invention discloses a construction method and an identification method of characteristic chromatograms of a senecio scandens medicinal material as well as decoction pieces, standard decoction and formula granules thereof, and relates to the technical field of traditional Chinese medicine identification. The construction method of the specific chromatogram comprises the following steps: extracting a to-be-detected sample with methanol to obtain a test solution; the method comprises the following steps: dissolving 5-caffeoylquinic acid, chlorogenic acid, caffeic acid, 4-caffeoylquinic acid, rutin, hyperoside, isoquercitrin and 4, 5-dicaffeoylquinic acid with methanol to obtain a reference solution; and a liquid chromatograph is adopted for determination. A chromatographic column of the liquid chromatograph takes phenyl-methyl polysiloxane as a stationary phase, acetonitrile as a mobile phase A and 0.05 vol%-0.3 vol% formic acid aqueous solution as a mobile phase B for gradient elution. The information of the characteristic chromatogram constructed by the method is rich, and the quality of the senecio scandens medicinal material, decoction pieces, standard decoction and formula granules can be quickly and comprehensively reflected.

The invention discloses a weed pathogenic bacterium spiropolyspora roseum JZ-28 and application thereof in weed prevention and removal, and belongs to the technical field of microorganisms. The weed pathogenic bacterium, namely the clonostachys rosea JZ-28, is preserved in the China General Microbiological Culture Collection Center (CGMCC), the preservation number is CGMCC No.41916, and the preservation date is April 15, 2025. The invention further discloses a preparation method of the clonostachys rosea. According to the invention, a weed pathogenic bacterium, namely the spiropolyspora pink JZ-28, is obtained through separation. Through identification, the strain has high pathogenicity to four weeds including chenopodium album, elsholtzia densa, malva verticillata and senecio scandens, the incidence rate of living weed plants reaches 70% or above, and the strain is safe to corn, oilseed rape, cucumber, tomato, eggplant, broad bean and pea, has the potential of being developed into a microbial herbicide for broad-leaf weeds, and is wide in application prospect.

The invention relates to the technical field of plant extraction, and provides a plurality of phenolic compounds in senecio scandens, and a preparation method and application thereof. The method comprises the following steps: crushing senecio scandens, adding ethyl acetate, and performing ultrasonic heating, stirring and extracting to obtain an extracting solution; carrying out rotary evaporation and vacuum concentration on the extracting solution to obtain a crude extract; dissolving the crude extract by using absolute ethyl alcohol through ultrasonic heating, carrying out gradient elution through a macroporous adsorption resin chromatographic column, and collecting an ethanol water eluent; and concentrating the ethanol water eluent under reduced pressure, stirring with a reverse-phase filler, loading with a dry method, packing with a wet method, and sequentially performing isocratic elution with a reverse-phase chromatographic column and purification with a gel column. The dissolution efficiency of phenolic compounds in senecio scandens is improved through ultrasonic and mild heating, the problems that components are degraded due to high temperature in traditional reflux extraction and time and solvent are consumed in dipping extraction are solved, and target component residues are reduced; and then through gradient elution of a chromatographic separation column, isocratic elution of a reversed-phase chromatographic column and purification of a gel column, the problem that phenols are similar in structure and easy to co-elute is accurately solved.

The present application relates to a kind of preparation method of Fugunkang composition and its detection method, the preparation method is cut into section, first using red koji and saccharomyces cerevisiae combined fermentation extraction, dregs is extracted with water before boiling, concentrate and extract the fermentation liquor and water, it is obtained.The metabolic function of microorganism is fully utilized, promote the release and absorption of effective components of traditional Chinese medicine in vivo, so as to improve the curative effect of traditional Chinese medicine, reduce the side effect of traditional Chinese medicine.The detection method includes spray agent in just bed, parsnip medicine thin layer identification and the content detection of rutin, hypericin;The thin layer identification can identify just bed and parsnip medicine under the same chromatographic condition, the content detection increases the content detection of hypericin on the basis of original, and the content of rutin and hypericin can be determined simultaneously, save the detection cost, ensure the quality of raw material and finished product.

The invention relates to a traditional Chinese medicine composition for treating ankylosing spondylitis, a medicine and a preparation method, and relates to the technical field of traditional Chinese medicines. The invention provides a traditional Chinese medicine composition for treating ankylosing spondylitis. The traditional Chinese medicine composition is prepared from the following raw materials: garden balsam stem, herb of Chinese rabdosia, spina gleditsiae, pangolin scales, camellia oleifera, radix angelicae, sargentgloryvine stem, folium artemisiae argyi, herba asari, leech, ficus microcarpa, semiliquidambar cathayensis, radix gleditsiae, sarcandra glabra, fructus liquidambaris and senecio scandens. The traditional Chinese medicine composition has the effects of dredging tendons and activating blood circulation, can deeply permeate into the body of a patient, enables swollen and calcified muscles and bones to recover to be normal, enables the skin color of a diseased region to recover to be normal, has a very good treatment effect on ankylosing spondylitis, is a neutral medicine, can be accepted by wet, cold and damp-heat constitutions, and is free of toxic and side effects. And the method has wide acceptability.

The invention relates to medicine, and more particularly to algology, and can be used in the treatment of pain. The present method includes oral administration of a pharmaceutical composition. Administration begins with a minimum single dose comprising: 1 drop or granule of the composition, dissolved in 15 ml of water, per 10 kg of the patient's weight. The minimum single dose is administered every 15 minutes. An individually tailored single dose is determined by adding up the minimum doses of the composition which induce a subjective sensation of a decrease in pain. The composition is administered in the individually tailored single dose at a dosage frequency of not more than 8 times a day on the first day and not more than four times a day on the second and subsequent days. The pharmaceutical composition contains equal quantities of Eupatorium perfoliatum in a 3D dilution, China officinalis, Secale comutum, Arnica montana in a 3C dilution, Rhus toxicodendron in a 4C dilution, Aconitum napellus, Belladonna, Bryonia alba, Ipecacuanha, Nux vomica in a 5C dilution, Mercurius solubilis in a 6C dilution, Abrotanum, Gallicum acidum, Heloderma suspectum, Senecio aureus in a 7C dilution, and Stramonium in a 9C dilution. The invention provides for a significant decrease in the pain sensations experienced by the patient, irrespective of the source of and reasons for the pain.

The invention relates to a plant extract eye lotion for relieving eye discomfort and a preparation method, and relates to the technical field of eye care, the eye lotion is prepared by compounding an eye protection extracting solution, an eye nourishing extracting solution and a moisturizing mixture, the eye protection extracting solution is prepared by smashing and extracting wild chrysanthemum flower, aloe, cassia seed and camphor tree extracting solution according to a specific proportion, and the moisturizing mixture is prepared by mixing the raw materials. The eye-nourishing extracting solution is prepared by smashing and extracting pearl powder, senecio scandens, felwort powder and menthol according to a specific proportion. Through scientific compatibility and synergistic effect of active ingredients of various traditional Chinese medicines, the eye cream can effectively moisten eyes and remarkably relieve various uncomfortable symptoms such as eye dryness, eye acerbity, soreness and swelling and blurred vision, and meanwhile, the product is mild in property, comfortable to use and high in safety.

The invention provides a method for detecting HPLC (high performance liquid chromatography) characteristic chromatograms of senecio scandens medicinal materials, decoction pieces, standard decoction and formula granules, which comprises the following steps: pre-treating raw materials of a test sample to obtain liquid to be detected; the pretreatment mode comprises solvent dissolution and extraction; measuring the liquid to be measured by adopting HPLC (High Performance Liquid Chromatography) to obtain HPLC characteristic chromatograms of the senecio scandens medicinal material, decoction pieces, standard decoction and formula granules; the preparation method comprises the following steps: preparing a reference substance solution, namely dissolving neochlorogenic acid, protocatechuic aldehyde, chlorogenic acid, caffeic acid, cryptochlorogenic acid, p-coumaric acid, chlorogenic acid methyl ester, rutin, hyperoside, isoquercitrin, chlorogenic acid ethyl ester, isorhamnetin-3-O-galactoside, quercitrin, isochlorogenic acid B, isochlorogenic acid A, isochlorogenic acid C, quercetin and kaempferol by adopting a solvent; obtaining a reference substance solution of the reference substance; the HPLC conditions are as follows: a chromatographic column is a phenyl column; a mobile phase A is an acetonitrile solution, a mobile phase B is a 0.3% phosphoric acid aqueous solution, and gradient elution is carried out; according to the method, a high performance liquid chromatography method is adopted, and an acetonitrile-0. 3% phosphoric acid solution is selected as a mobile phase for gradient elution; the method comprises the following steps: taking neochlorogenic acid, protocatechuic aldehyde, chlorogenic acid, caffeic acid, cryptochlorogenic acid, p-coumaric acid, chlorogenic acid methyl ester, rutin, hyperoside, isoquercitrin, chlorogenic acid ethyl ester, isorhamnetin-3-O-galactoside, quercitrin, isochlorogenic acid B, isochlorogenic acid A, isochlorogenic acid C, quercetin and kaempferol as reference substances; the HPLC characteristic chromatogram method of the senecio scandens medicinal material, the decoction pieces, the standard decoction and the formula granules is established, and more scientific technical means are provided for controlling the medicinal quality of the senecio scandens medicinal material, the decoction pieces, the standard decoction and the formula granules.

The invention relates to the technical field of traditional Chinese medicines, and discloses an external Chinese herbal medicine formula for inhibiting ocular axis growth and a preparation method. The formula comprises the following components in parts by mass: 2 to 5 parts of bat dung, 15 to 25 parts of senecio scandens, 5 to 8 parts of safflower, 6 to 10 parts of snow lotus herb, 5 to 9 parts of Chinese starjasmine stem, 8 to 12 parts of scutellaria baicalensis, 8 to 12 parts of coptis chinensis, 8 to 12 parts of golden cypress, 15 to 25 parts of wild chrysanthemum flower, 6 to 10 parts of mint, 1 to 2 parts of borneol, 25 to 35 parts of calamine, 8 to 12 parts of compound of glauber-salt and liquorice, 1 to 3 parts of storax, 4 to 6 parts of lithospermum, 4 to 6 parts of cassia seed, 6 to 10 parts of butterflybush flower, 5 to 8 parts of pearl liquid and honey. The gel is prepared from the following components in parts by weight: 1-6 parts of a silk fibroin-alginic acid dynamic gel matrix, 8-12 parts of butterflybush flower nanocrystals, 4-6 parts of magnet-indigo naturalis composite particles and 70-80 parts of the silk fibroin-alginic acid dynamic gel matrix. Targeted delivery, magnetically controlled slow release and dynamic gel technologies are fused, and accurate delivery, long-acting stable release and controllable irritation of active ingredients are realized.

The invention discloses a traditional Chinese medicine composition for treating beriberi, eczema and heat miliaria, and belongs to the technical field of traditional Chinese medicine preparations. The traditional Chinese medicine composition is prepared from ginger powder, wormwood, green prickleyash, artemisia apiacea, sambucus chinensis, senecio scandens, black pepper and flos caryophylli. A broad-spectrum antifungal network is formed by the green prickleyash and the flos caryophylli, and dual inhibition is achieved on beriberi pathogenic bacteria and eczema secondary infection bacteria; artemisia argyi and artemisia apiacea are in cold-warm compatibility to regulate damp-heat toxin bidirectionally, the former warms channels, dispels cold and improves microcirculation, the latter clears heat, cools blood and inhibits inflammatory factors, sambucus chinensis can accelerate healing of an erosive surface, black pepper can expand blood capillaries to promote medicine permeation, and meanwhile, the warming, dredging and cold dispelling effects of ginger powder are improved. According to the invention, wormwood and green prickleyash are used as monarch drugs to mainly attack core pathogenesis, ginger powder and black pepper are used as ministerial drugs to enhance transdermal absorption, and cold-warm balance prevents pure heat-clearing drugs from aggravating dampness stagnation or pure warm drugs from stimulating skin.

The present invention relates to the technical field of traditional Chinese medicine, and in particular to a composition for treating cervicitis, comprising the following raw materials in parts by weight: 40-50 parts of euphorbia pulex root, 30-40 parts of groundsel, and 10-20 parts of white wormwood. The composition for treating cervicitis of the present invention is composed of euphorbia pulex root, groundsel, and white wormwood, and combines the anti-inflammatory and detoxifying effects of euphorbia pulex root with the heat-clearing and detoxifying effects of groundsel, as well as the sore-healing and pain-relieving effects. The combined use of the various prescriptions of the present invention interacts with each other, and has strong heat-clearing and detoxifying, antibacterial and anti-inflammatory, analgesic, damp-removing, and necrotizing effects, thereby having a good therapeutic effect on cervicitis. Mulberry branches have the effects of promoting blood circulation, removing blood stasis, eliminating edema, and relieving itching. After adding a small amount of mulberry branches, the effect of treating cervicitis is further improved, and the therapeutic effect is significant.

The invention discloses a decoction preparation method of a traditional Chinese medicine composition of abelmoschus manihot medicated bath soap, and relates to the technical field of traditional Chinese medicine external preparations. Comprising the following steps: (1) raw material compatibility and pretreatment: taking 10-25 parts by mass of abelmoschus manihot, 5-15 parts by mass of tobacco leaf stalks, 8-20 parts by mass of cacumen biotae, 5-15 parts by mass of saponin, 8-20 parts by mass of senecio scandens, 5-15 parts by mass of polygonum multiflorum, 5-15 parts by mass of angelica sinensis, 5-15 parts by mass of folium mori, 5-15 parts by mass of cortex dictamni, 5-15 parts by mass of radix sophorae flavescentis and 10-25 parts by mass of sodium carbonate. The adjuvant cacumen biotae is capable of removing dandruff and growing hair, and the conductant borneol is transdermal and guides channels; a plurality of medicinal materials have a synergistic effect and have a treatment effect on inflammation, pruritus, desquamation and other links of skin diseases; a superfine grinding technology is adopted, so that the dissolution rate of effective components is greatly improved; the extraction efficiency is ensured and the loss of volatile components is avoided by adopting a segmented boiling process; a three-stage filtering system ensures the purity and fineness of the product; the traditional Chinese medicines are combined with the modern soap agent, so that the soap has dual functions of cleaning and treatment.

The present invention provides a kind of Chinese medicine preparation for treating or improving depression, and relates to the technical field of Chinese medicine pharmacy.Chinese medicine preparation of the present invention is made of 10 medicinal materials in total, including safflower seeds, citron, toosendan seeds, cyperus rotundus, herba communis, senecio, fennel, jujube, fenugreek, and liquorice. All medicines are used to soothe the liver and regulate qi, clear the liver and purge fire, regulate the liver and spleen, and clear the meridians and warm the kidney yang, so that liver depression can be solved, qi can be smooth, liver fire can be cleared, and depression can be removed.Chinese medicine preparation of the present invention has a significant improvement effect on the depressive-like behavior of depression mice, and has a significant inhibitory effect on neuroinflammation. At the same time, Chinese medicine preparation of the present invention is combined with western medicine to treat depression, and has a significant effect, which can significantly reduce the HAMD-17, HAMA and TESS scores of depression patients after treatment, significantly improve the depression and anxiety of patients, and alleviate adverse reactions. Chinese medicine preparation of the present invention provides a new idea for traditional Chinese medicine treatment of depression.

The invention provides an external traditional Chinese medicine composition with a bacteriostatic effect and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine compositions. The traditional Chinese medicine composition comprises 20-40 parts of pepper, 20-40 parts of fructus cnidii, 10-30 parts of ligusticum, 5-15 parts of pogostemon cablin, 20-40 parts of schizonepeta, 10-30 parts of senecio scandens and 20-40 parts of mint. A response surface experiment design is adopted to optimize an extraction process of traditional Chinese medicinal materials and medicine residues, and the content of effective components such as total flavonoids in the extract is increased; the oil-soluble matrix and the water-soluble matrix are selected, so that the water-soluble medicine components and the oil-soluble medicine components can be better mixed, and the stability is high. The traditional Chinese medicine composition disclosed by the invention can inhibit the formation of bacterial cell membranes and destroy the structures of the bacterial cell membranes, and the permeability of the cell membranes is improved, so that macromolecular substances and proteins are leaked; the intracellular ATP content is reduced, and the extracellular alkaline phosphatase is increased, so that the growth of bacteria is finally inhibited or the bacteria are killed. According to the extraction process, effective components of the medicine are extracted to the maximum extent, and efficient utilization of the medicinal materials is guaranteed.

The invention relates to the technical field of rice planting, in particular to a herbal nutrient solution as well as a preparation method and application thereof in seed cultivation. The herbal nutrient solution comprises the following components: cinnamomum tamala, platycladus orientalis, radix isatidis, the root of kudzu vine, radix semiaquilegiae, black bamboo, dryopteris pilosa, ardisia japonica, lindera glauca root, coptis chinensis, buddleia, cattail, abelmoschus esculentus, senecio scandens, lycopodium clavatum, lygodium japonicum, purple perilla, canna, chenopodium album, folium artemisiae argyi, fig, pteris multiflora, chinaroot greenbrier, rhizoma smilacis glabrae, folium isatidis, kiwi fruit and folium mori. The root system of a grain seedling cultivated by the herbal nutrient solution provided by the invention grows more vigorously, and the grain seedling is higher and more robust, which indicates that the stress resistance of the plant is better; and moreover, the obtained rice is higher in yield and better in quality.

This invention discloses a SNP marker and detection primer pair associated with the adventitious root primordium trait of *Senecio scandens* with stem nodules, and its application, belonging to the field of molecular biology technology. Based on SNP marker technology, this invention develops an SNP marker and detection primer pair linked to the adventitious root primordium trait of *Senecio scandens* with stem nodules. This invention involves phenotypic identification of mutants induced by EMS mutagenesis in *Senecio scandens* with stem nodules, followed by isolation, purification, population construction, and genetic analysis combined with Mutmap. + The SNP marker associated with adventitious root primordia is located at 10,433,968 bp on chromosome 4 of *Senecio scandens*, involving a C / T mutation. When the genotype is T, *Senecio scandens* lacks adventitious root primordia. This invention's SNP molecular marker can screen F2 populations at the early cotyledon stage, identifying mutants and wild types without phenotypic differences, thus improving screening efficiency, shortening the breeding cycle, and demonstrating value in marker-assisted breeding.

A new and distinct cultivar of Senecio plant named ‘Sene Isifuro’, characterized by its compact, upright and uniformly mounded plant habit; vigorous growth habit; freely branching habit; freely flowering habit; daisy-type inflorescences with spoon-shaped ray florets with dark violet-colored upper surfaces and light violet-colored lower surfaces; and good garden performance.

The invention discloses a transdermal detumescence itching-relieving anti-fatigue eye patch and a preparation method thereof, the transdermal detumescence itching-relieving anti-fatigue eye patch comprises a transdermal patch and a transdermal agent, the transdermal agent is prepared by blending traditional Chinese medicine components and auxiliary materials, the traditional Chinese medicine components comprise honeysuckle flowers, wild chrysanthemum flowers, cassia seeds, rhizoma dioscoreae nipponicae, folium isatidis, mint, dandelions, spina gleditsiae, fructus cnidii, herba schizonepetae, radix saposhnikoviae, radix sophorae flavescentis, senecio scandens, cortex dictamni, pearl powder, borneol, selfheal and thunberg fritillary bulbs; the auxiliary material is yellow vaseline. The eye pad disclosed by the invention has the effects of clearing away heat and toxic materials, soothing the liver and promoting the circulation of qi, removing heat and dampness, softening hardness to dissipate stagnation, diminishing swelling and expelling pus, and eliminating dampness and relieving itching, and achieves the purposes of curing eyelid inflammation, relieving itching, resisting allergy and resisting fatigue.

The invention discloses a pharmaceutical composition for treating hypertrophic scars and / or keloids. The pharmaceutical composition is prepared from the following raw materials in parts by weight: 15-25 parts of gallnut, 15-25 parts of smoked plum, 15-25 parts of senecio scandens, 15-25 parts of fructus cnidii, 10-20 parts of radix angelicae, 10-20 parts of cortex lycii radicis, 170-230 parts of vinegar and 170-230 parts of honey. The composition disclosed by the invention has the effects of detoxifying, diminishing swelling, astringing dampness and relieving itching. The traditional Chinese medicine composition has obvious effects on hypertrophic scars and keloids formed after trauma, operation, burns and scalds, acne, folliculitis and other inflammations, and itching and pain caused by the hypertrophic scars and keloids.

This invention discloses a traditional Chinese medicine composition for treating wind-heat type common cold and its preparation method, relating to the field of traditional Chinese medicine technology. The composition is made from the following raw materials in parts by weight: 15-20 parts of *Ilex asprella*, 10-15 parts of mulberry leaf, 4-10 parts of wild chrysanthemum, 4-10 parts of *Viola yedoensis*, 10-15 parts of *Senecio scandens*, and 4-10 parts of dandelion. The preparation method includes: mixing the raw materials, soaking in 6-10 times the amount of water for 15-60 minutes; decocting twice, maintaining the boil for 1.5-2 hours each time, filtering and combining the filtrates; concentrating to a relative density of 1.14-1.18 at 80°C, cooling, adding 95% ethanol to achieve an alcohol content of 65-70%, stirring and standing for 12-24 hours, collecting the supernatant; recovering the ethanol under reduced pressure to obtain an extract and concentrating to a relative density of 1.25-1.30 at 80°C. This invention solves the problems of existing drugs for treating wind-heat colds having a narrow range of indications, insufficient extraction of effective components or incomplete removal of impurities in the preparation process, and the need to improve product quality stability.

The application discloses a kind of external use herbal essence with improving skin itching, which is composed of Tripterygium wilfordii Hook.f., Selaginella tamariscina, Senecio scandens Buchen, Viburnum dilatatum, water wong root and chestnut shell.The present prescription combines wind-heat, damp-heat and blood-heat, and has the effects of clearing heat and cooling blood, dispelling wind and relieving itching.It has achieved good effects in treating patients with skin itching, especially in treating peeling, dandruff and epidermal crack caused by dry skin after skin itching.The present application not only solves the problem of skin itching, but also makes the skin smooth and moisturized after treatment, and solves the problem of dry skin.Compared with western medicine, the present application has no side effects, fast curative effect, low cost and convenient use.

The application discloses a method for separating alkaloid compounds in Senecio scandens Buchen. The method comprises the following steps: (1) subjecting dried medicinal materials of Senecio scandens Buchen to alcohol extraction, and then concentrating to obtain an ethanol extract; (2) dispersing the ethanol extract with water, and then sequentially extracting with petroleum ether and ethyl acetate to obtain a petroleum ether part, an ethyl acetate part and a water part; (3) subjecting the water part to D101 macroporous resin separation and purification to obtain an alkaloid crude product; (4) subjecting the alkaloid crude product to medium-pressure preparative liquid chromatography separation to obtain a concentrate; and (5) subjecting the concentrate to preparative high-performance liquid chromatography purification to obtain a product. The alkaloid compounds are successfully obtained by adopting the ethanol extraction, D101 macroporous resin column chromatography, medium-pressure preparative liquid chromatography and preparative HPLC separation and purification, the operation method is simple and rapid, and the compounds obtained by the method have high purity.

The invention discloses distiller's yeast of Guizhou Miao rice wine. The invention is characterized in that the distiller's yeast is mainly prepared from the following raw materials: sticky rice, glutinous rice, mother yeast, actinidia eriantha, Chinese actinidia, paederia scandens, honeysuckle, ficus tikoua, melastoma dodecandrum, betula luminifera, schisandra lancea, senecio scandens, white senecio scandens, inula cappa, gerbera piloselloides, indigofera bungeana, desmodium wave, pueraria lobata, gaultheria yunnanensis, pungent litse fruit, raspberry, raspberry, endive, camellia and horsetail. , red bayberry and taxus chinensis.

The invention provides an extraction method of senecio scandens plant polysaccharide and application of the senecio scandens plant polysaccharide in preparation of a medicine for preventing and / or pneumonia, and belongs to the technical field of polysaccharide extraction. The three kinds of senecio scandens polysaccharides are extracted from senecio cannabina, senecio scandens and senecio scandens in shade by utilizing a water extraction and alcohol precipitation method. According to the invention, a rat pneumonia model successfully established by adopting an LPS combined smoke inhalation method is taken as an experimental subject, drug effect evaluation experiments of three kinds of senecio scandens polysaccharides are carried out, and results show that the three kinds of senecio scandens polysaccharides can be used for reducing the cough and asthma times of pneumonia rats, prolonging the cough latency period of the pneumonia rats and improving the oxidation resistance; the senecio cannabina polysaccharide has a certain protection effect on lung tissue injury, wherein the senecio cannabina polysaccharide has the best effect. The invention provides the application of the senecio scandens plant polysaccharide in preparation of the medicine for preventing and / or pneumonia, and a new means is provided for clinical treatment of pneumonia.

The invention discloses a weed pathogenic strain HL-12 and application of the weed pathogenic strain HL-12 in weed control, and belongs to the technical field of microorganisms. The weed pathogenic strain HL-12 disclosed by the invention is preserved in the China General Microbiological Culture Collection Center (CGMCC), the preservation number is CGMCC No.41917, and the preservation date is April 15, 2025. The weed pathogenic strain HL-12 disclosed by the invention has the advantages that the weed pathogenic strain HL-12 is named as HL-12, and the weed pathogenic strain HL-12 is named as HL-12; according to the invention, a pathogen HL-12 is obtained through separation by taking bipolaris as a research object for preventing and controlling weeds. Through identification, the pathogenic bacterium HL-12 has high pathogenicity to four weeds such as chenopodium album, elsholtzia densa, malva verticillata and senecio scandens, the morbidity of living weed plants reaches 90% or above, the pathogenic bacterium HL-12 is safe to wheat and eggplants, and it is proved that the strain has the potential to be developed into a microbial herbicide for broadleaf weeds in wheat fields.

The invention discloses a preparation method of an extract for removing pyrrolizidine alkaloids (PAs) in plants by a one-step method. According to the method, a synchronous reaction system of acid extraction, alkali precipitation and extraction is constructed, and a traditional multi-step process is integrated into one step. The method specifically comprises the following steps: carrying out acid extraction by adopting an ethanol-water solution containing organic acid, directly adding an ammonia water-organic solvent mixed solution to realize synchronous alkalization and extraction, and separating a water phase to obtain a low-toxicity extract. The method has the outstanding advantages that the PAs removal rate is high (greater than or equal to 98%), effective components are well retained (flavonoid is greater than or equal to 95%) and the like. The content of PAs in the obtained extract is less than or equal to 0.001%, completely meets the limit standard of Chinese Pharmacopoeia, and is suitable for safe utilization of medicinal plants containing PAs, such as senecio scandens and tussilago farfara. The method is simple in process, low in cost and suitable for industrial production, and a reliable solution is provided for modern development of traditional Chinese medicines containing PAs.

This invention relates to the field of pharmaceutical technology, specifically to a combination of traditional Chinese medicine (TCM) preparations for antibacterial and health-promoting treatment throughout the entire life cycle, and its method of use. The kit comprises three independent preparations: a rapid-release protective spray using Litsea cubeba essential oil nanoemulsion as a solvent, loaded with a compound alcoholic extract derived from Polygonum cuspidatum, Senecio scandens, Clematis chinensis, and Glycyrrhiza uralensis in a weight ratio of 4:3:1:1; a sustained-release repair gel patch using a thermosensitive poloxamer F127 and gelatin-sodium alginate double-network hydrogel as a matrix, encapsulating a concentrated aqueous extract obtained from freeze-dried powders of Polygonum cuspidatum, Portulaca oleracea, dried ginger, Bletilla striata, and honey in a weight ratio of 4:2:1:2:1; and a soluble healing-promoting bath film, a biodegradable film made from polyvinyl alcohol and carboxymethyl chitosan via a casting method, in which ultrafine powders of the core active pharmaceutical ingredient and nano-silver-bioglass composite material are dispersed. This application aims to construct a multi-layered, responsive product system from rapid protection to deep repair.

The invention relates to the technical field of traditional Chinese medicines, and particularly discloses a traditional Chinese medicine composition for improving eyesight and a preparation method thereof. The traditional Chinese medicine composition for improving eyesight is prepared from the following raw materials in parts by weight: 10 to 20 parts of fructus lycii, 5 to 10 parts of flos chrysanthemi, 15 to 30 parts of flos buddlejae, 1 to 5 parts of herba menthae, 1 to 5 parts of indigo naturalis, 1 to 5 parts of bamboo leaves, 10 to 30 parts of semen cassiae, 1 to 5 parts of folium mori, 1 to 5 parts of pearl, 1 to 5 parts of herba senecionis scandentis, 5 to 15 parts of herba equiseti hiemalis and 1 to 10 parts of borneol. The traditional Chinese medicine composition disclosed by the invention has the beneficial effects that through the synergistic effect of multiple traditional Chinese medicines, the traditional Chinese medicine composition has the effects of clearing liver channel and head and eye wind-heat and fire toxin, dispelling wind and heat, detoxifying, removing nebula, nourishing yin and relieving urgency, and can quickly and effectively eliminate inflammation and stimulation symptoms such as red, swollen, hot, pain, itching, astringent, tears, gums and the like of eyes; corneal inflammation and opacity are relieved, and blurred vision caused by inflammation or ocular opacity is improved; the liver heat type asthenopia and concomitant blurred vision can be relieved; certain antioxidant protection and nutrition support are provided for eye tissues; and the effect of efficiently and directly reaching the disease site is ensured through the powerful channel-inducing medicine borneol.

The invention discloses a suction type rosemary moxibustion traditional Chinese medicine composition and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine preparations. The composition is prepared from semen cassiae, dendrobe, senecio scandens, folia perillae acutae, agilawood powder, folium artemisiae argyi, fennel, asarum, ligusticum wallichii, radix angelicae and plant source protease according to a specific weight part ratio. The preparation method comprises the following steps: carrying out superfine grinding on the medicinal materials except the agilawood, adding water for wetting, carrying out enzymolysis reaction by utilizing plant source protease, drying at low temperature, adding the agilawood powder, uniformly mixing, and finally sterilizing and sub-packaging. A traditional Chinese medicine formula and a modern preparation technology are combined, and the prepared fragrant moxibustion product can directly act on the respiratory tract and the nervous system in an inhalation way, has the effects of restoring consciousness, soothing the nerves, opening orifices and resisting allergy and is used for relieving symptoms such as dizziness, dizziness, insomnia, dreaminess and allergic rhinitis. The product is safe and convenient to use, quick to take effect and stable in product quality.

This invention discloses a method for preparing edible Chinese herbal eye drops using traditional distillation techniques, belonging to the field of Chinese herbal eye preparation technology. It addresses the problems of low safety, poor user experience, low component utilization, and insufficient adaptability to various scenarios in existing eye care preparations. The method uses medicinal and edible herbs such as *Senecio scandens* and *Eriocaulon buergerianum* as the core ingredients, with purified water as the only excipient. The process involves purification, processing, traditional static conditioning, distillation to obtain the dew, followed by refined treatment through low-temperature extraction, multi-stage ultrafiltration, and low-temperature deodorization. Finally, the product is aseptically filled to a fixed volume. This invention allows for adjustments to the formula and replacement of processes according to needs. It can also be formulated into freeze-dried powder or a special dosage form suitable for nebulizers. The resulting eye drops are colorless, with a pH of 6.5-7.0, meeting edible standards. The active ingredients are molecularly dissolved, allowing for eye drops, nebulization, external application, and oral administration. It is safe and non-irritating, with high component utilization, adaptable to multiple scenarios, green and additive-free, suitable for long-term eye care, and safe for the elderly and children.