Percutaneous drug delivery system based on porous microneedle structure

Abstract

The invention discloses a percutaneous drug delivery system based on a porous microneedle structure. The percutaneous drug delivery system comprises a porous microneedle, a polymer film, a pump, a liquid inlet pipe, a liquid outlet pipe, a liquid medicine feeding tank and a liquid medicine storage tank, wherein the polymer film wraps part of the microneedle, so that a tiny part of the needle point and a microneedle base are exposed out of the porous structure; the porous microneedle is connected with the liquid medicine feeding tank, the liquid medicine feeding tank is connected with one end of the liquid outlet pipe, the other end of the liquid outlet pipe is communicated with one end of the liquid inlet pipe in the pump, and the other end of the liquid inlet pipe is connected with the liquid medicine storage tank. The microneedle has a porous structure, therefore, liquid medicine can enter into an organism through multiple channels; and the pump is provided with a power supply and has stable flow. The whole system is simple in structure, easy to make, small in volume and high in efficiency.

Description

technical field [0001] The invention relates to a device in the field of biomedicine, in particular to a transdermal drug delivery system based on a porous microneedle structure. Background technique [0002] In recent years, with the continuous advancement of MEMS (Micro-Electro-Mechanical Systems) technology, many microneedles used in medical transdermal drug delivery have been processed, but these microneedles still require manual operation during drug delivery. How to reduce manual operations and automate drug delivery is an urgent problem to be solved. There are generally two types of transdermal drug delivery systems: hollow microneedle drug delivery system and solid microneedle drug delivery system. Compared with the solid microneedle drug delivery system, the hollow microneedle drug delivery system is conducive to continuous control and is easier to automate. The solid system needs to coat the drug on the surface of the needle body, and it needs to be coated again ...

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to overcome the deficiencies of the prior art, and propose a transdermal drug delivery system based on a porous microneedle structure, so that the driving force of the drug is more effective and durable, and the efficiency of the drug entering the organism is higher, so as to solve the problem of drug passing through directly Direct channel diffusion is slow, driving power is insufficient, etc., and the present invention has the characteristics of simple manufacturing process and more favorable control

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