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48 results about "Percutaneous techniques" patented technology

This technique is known as the modified Seldinger technique. More generally, "percutaneous", via its Latin roots means, 'by way of the skin'. An example would be percutaneous drug absorption from topical medications.

Percutaneous technique and implant for expanding the spinal canal

InactiveUS7166107B2Simple and safe and permanent and minimally invasiveRelieve stressInternal osteosythesisDiagnosticsOsteotomyBiomedical engineering
The present invention expands a spinal canal by drilling a cylindrical passage in each pedicle of a vertebra, making a circumferential pedicle cut (osteotomy) through each pedicle from within the passage, separating each pedicle cut by inserting an implant into the passage which distracts the pedicle cut to expand the spinal canal, and securing each pedicle cut, allowing the vertebra to heal with the spinal canal expanded. The implant includes an outer sleeve, an inner bolt, and expandable flanges. The outer sleeve includes an upper portion and a lower portion, with the expandable flanges connected to the lower portion and housed within the upper portion. Rotation of the inner bolt causes the upper and lower portions of the outer sleeve to separate, causing the pedicle cut to widen and the expandable flanges to radially extend into and stabilize the widened pedicle cut to effectuate expansion of the spinal canal.
Owner:DEPUY ACROMED INC +2

Expandable percutaneous sheath

ActiveUS20050124937A1Small cross-sectional profileEasy to insertGuide needlesCannulasPercutaneous nephrostomyTherapeutic Procedure
Disclosed is an expandable percutaneous sheath, for introduction into the body while in a first, low cross-sectional area configuration, and subsequent expansion to a second, enlarged cross-sectional configuration. The sheath is maintained in the first, low cross-sectional configuration by a tubular restraint. In one application, the sheath is utilized to provide access for a diagnostic or therapeutic procedure such as percutaneous nephrostomy or urinary bladder access.
Owner:ONSET MEDICAL

Systems and methods for performing minimally invasive spinal surgery with a robotic surgical system using a percutaneous technique

Described herein are systems, apparatus, and methods for precise placement and guidance of tools during surgery, particularly spinal surgery, using minimally invasive surgical techniques. Several minimally invasive approaches to spinal surgeries were conceived, percutaneous technique being one of them. This procedures looks to establish a skin opening as small as possible by accessing inner organs via needle-puncture of the skin. The percutaneous technique is used in conjunction with a robotic surgical system to further enhance advantages of manual percutaneous techniques by improving precision, usability and / or shortening surgery time by removal of redundant steps.
Owner:KB MEDICAL SA

Intramedullary Fixation Device for Small Bone Fractures

A fracture fixation system particularly useful for bones of the hand and foot is disclosed. The system uses curved shape-memory alloy (e.g., Nitinol) wires that have a predetermined radius of curvature to accommodate different sized bones. These shape-memory alloy wire forms can be inserted into phalanx, metacarpal or metatarsal bones via a percutaneous technique. The technique uses small skin incisions; a specialized drill guide that has holding K-wires to maintain fixation of the drill guide to the bone so that it does not lose the insertion point; a specialized drill as well as a specialized wire cutter and advancement tool to make sure that the level of the wire is below the level of the outer cortical bone. Shape-memory alloy (e.g., Nitinol) based wires with a pre-bent curve have an advantage over the typical standard K-wire in that they can spring back to their predetermined memory shape when inserted into the intramedullary canal of the bone and heated, i.e., a more aggressive curve. By increasing their bending or flexion to increase the arc of curvature, this allows fixation points for the wire, essentially locking it to bone.
Owner:MAYO FOUND FOR MEDICAL EDUCATION & RES

Expandable percutaneous sheath

ActiveUS8092481B2Prevent rotationSurgeryDilatorsPercutaneous nephrostomyTherapeutic Procedure
Disclosed is an expandable percutaneous sheath, for introduction into the body while in a first, low cross-sectional area configuration, and subsequent expansion to a second, enlarged cross-sectional configuration. The sheath is maintained in the first, low cross-sectional configuration by a tubular restraint. In one application, the sheath is utilized to provide access for a diagnostic or therapeutic procedure such as percutaneous nephrostomy or urinary bladder access.
Owner:ONSET MEDICAL CORP

Microneedle transdermal drug delivery paste for treating rheumatoid arthritis and preparation method of microneedle transdermal drug delivery paste

ActiveCN109528695AImprove the efficiency of transdermal deliveryAvoid wastingAntipyreticAnalgesicsNatural barrierTissue fluid
The invention discloses a microneedle transdermal drug delivery paste for treating rheumatoid arthritis. The microneedle transdermal drug delivery paste comprises a base layer, and a plurality of microneedles, wherein the microneedles are vertically fixed on the surface of the base layer and are arranged at intervals mutually; the microneedles are provided with active medicine components. In treatment, the microneedles puncture through skin cuticle and enter epidermis, and then medicines stored in the microneedles can be released into tissue fluids, so that the purpose of treatment is achieved, defects that a conventional transdermal drug delivery preparation has difficulties in breaking through natural barriers of cuticle and is low in biological utilization rate can be overcome, and thetransdermal drug delivery rate of medicines can be greatly increased. The dissoluble microneedle paste comprises one or more active medicinal components for treating rheumatoid arthritis, and meanwhile a synergetic effect can be taken into play; due to puncture functions of the microneedles, auxiliary treatment can also be achieved. The invention further provides a preparation method of the microneedle transdermal drug delivery paste. By adopting the preparation method, medicines of different types of dissolubility can be carried by one same dissoluble microneedle paste, and multiple medicinescan be also carried to achieve synergetic drug delivery treatment.
Owner:BENGBU MEDICAL COLLEGE

Micro-needle array chip, percutaneous administration device, percutaneous administration patch and preparation method thereof

The invention relates to a micro-needle array chip, a transdermal delivery device, a transdermal delivery patch and a preparation method thereof, wherein a micro-needle is obliquely fixed on a substrate at a set angle, the upper surface of the needle is an elliptic plane parallel to the substrate or obliquely provided with an acute angle, the needle is further treated to have more edge angles, a metal wire bar or tube penetrates a non-metallic material substrate such as polymer and the like along a certain angle, and then a nick of the metal wire bar or tube on the substrate is grinded and polished; and photosensitive resist patterns are formed nearby the nick at one end by adopting photoetching and etching technology, then the metal wire bar or tube is subjected to chemical or electrochemical corrosion to form a needle point and the photosensitive resist is removed, the surface of the manufactured solid micro-needle array chip can be covered with drugs, and the manufactured solid micro-needle array chip can deliver liquid medicine or extract body fluid. The method avoids the skin plugging a transfusion hole, is easy to adjust and control the maximum penetrating depth of the micro-needle, and is suitable for percutaneous transportation of biological macromolecular drugs and cosmetics and skincare and new percutaneous preparation of the prior drugs.
Owner:TSINGHUA UNIV

Flexible Catheter System

A percutaneous delivery system with a high degree of flexibility is provided. In one embodiment, the system includes a catheter having a portion comprising multiple segments, linked in series by at least one connecting wire. Joints between the multiple segments provide a high degree of flexibility. In some embodiments, only a distal portion is made up of segments. In other embodiments, the whole length of the catheter is made up of segments. Manipulation of the at least one connecting wire enables manipulation of the segments to flex a portion of the catheter. In one aspect, the invention provides a delivery system that reduces the impact of the delivery system on the final release position of the implant delivered. The delivery system can be used to deploy and / or retrieve implantable medical devices, for example, patent foramen ovale (PFO) occluder.
Owner:WL GORE & ASSOC INC

Expandable percutaneous sheath

Disclosed is an expandable percutaneous sheath, for introduction into the body while in a first, low cross-sectional area configuration, and subsequent expansion to a second, enlarged cross-sectional configuration. The sheath is maintained in the first, low cross-sectional configuration by a removable tubular restraint. In one application, the sheath is utilized to introduce a formed in place orthopedic fixation rod such as for use in spinal fixation procedures.
Owner:WARSAW ORTHOPEDIC INC

Percutaneous delivery systems for anchoring an implant in a cardiac valve annulus

Mitral valve prolapse and mitral regurgitation can be treating by implanting in the mitral annulus a transvalvular intraannular band. The band has a first end, a first anchoring portion located proximate the first end, a second end, a second anchoring portion located proximate the second end, and a central portion. The central portion is positioned so that it extends transversely across a coaptive edge formed by the closure of the mitral valve leaflets. The band may be implanted via translumenal access or via thoracotomy.
Owner:HEART REPAIR TECH INC

Percutaneous osseointegrated implant assembly for use in supporting an exo-prosthesis

ActiveUS20140195002A1Easy to installReduce dermatological complicationBone implantJoint implantsProsthesisBone ingrowth
An implant assembly for a long bone is adapted to support an exo-prosthesis. The assembly includes a stem, a subdermal component and a percutaneous post. The stem has a proximal end that is adapted to be received in a surgically prepared medullary canal of the long bone, and a distal end having a surface that is adapted to promote bone ingrowth. The subdermal component includes a proximal portion that is adapted for attachment to the distal end of the stem, and a fixation surface that is adapted to promote soft tissue fixation. The percutaneous post has a proximal end that is adapted to be attached to the subdermal component.
Owner:UNIV OF UTAH RES FOUND

Expandable percutaneous sheath

ActiveUS20060200188A1Minimally invasiveGuide needlesEar treatmentPercutaneous nephrostomyTherapeutic Procedure
Disclosed is an expandable percutaneous sheath, for introduction into the body while in a first, low cross-sectional area configuration, and subsequent expansion to a second, enlarged cross-sectional configuration. The sheath is maintained in the first, low cross-sectional configuration by a tubular restraint. In one application, the sheath is utilized to provide access for a diagnostic or therapeutic procedure such as percutaneous nephrostomy or urinary bladder access.
Owner:ONSET MEDICAL CORP

Percutaneous controlled releasing material using nano-sized polymer particles and external application agent containing the same

A percutaneous releasing material and agent having characteristics that include a high stability of an active agent in the formulation, a high topical absorption rate, decreased irritation on the skin, and an increased tactile comfort. The percutaneous releasing material incorporates an external application agent composition that is prepared by using nanometer-sized polymer particles, i.e., particles having a size or diameter between approximately 1 nm and approximately 500 nm, and more preferably having a size between about 30 nm and about 150 nm. Further, the percutaneous releasing material and agent according to the present invention incorporate polymer particles that preferably contain a physiologically active agent that more readily penetrates through the stratum corneum to the upper layer of the dermis, whereby the physiologically active agent is effused into the skin while staying in the upper layer of dermis.
Owner:KWON SUN SANG +7

Percutaneous drug delivery system based on porous microneedle structure

The invention discloses a percutaneous drug delivery system based on a porous microneedle structure. The percutaneous drug delivery system comprises a porous microneedle, a polymer film, a pump, a liquid inlet pipe, a liquid outlet pipe, a liquid medicine feeding tank and a liquid medicine storage tank, wherein the polymer film wraps part of the microneedle, so that a tiny part of the needle point and a microneedle base are exposed out of the porous structure; the porous microneedle is connected with the liquid medicine feeding tank, the liquid medicine feeding tank is connected with one end of the liquid outlet pipe, the other end of the liquid outlet pipe is communicated with one end of the liquid inlet pipe in the pump, and the other end of the liquid inlet pipe is connected with the liquid medicine storage tank. The microneedle has a porous structure, therefore, liquid medicine can enter into an organism through multiple channels; and the pump is provided with a power supply and has stable flow. The whole system is simple in structure, easy to make, small in volume and high in efficiency.
Owner:SHANGHAI JIAO TONG UNIV

Percutaneous osseointegrated implant assembly for use in supporting an exo-prosthesis

An implant assembly (30) for a long bone is adapted to support an exo-prosthesis. The assembly (30) includes a stem (22), a subdermal component (24) and a percutaneous post (26). The stem (22) has a proximal end (34) that is adapted to be received in a surgically prepared medullary canal of the long bone, and a distal end (4) having a surface that is adapted to promote bone ingrowth. The subdermal component (24) includes a proximal portion (44) that is adapted for attachment to the distal end (40) of the stem (22), and a fixation surface (55) that is adapted to promote soft tissue fixation. The percutaneous post (26) has a proximal end that is adapted to be attached to the subdermal component (24).
Owner:UNIV OF UTAH RES FOUND +1

Percutaneous technique and implant for expanding the spinal canal

InactiveUS20070219555A1Simple and safe and permanent and minimally invasiveRelieve stressInternal osteosythesisJoint implantsOsteotomyBiomedical engineering
The present invention expands a spinal canal by drilling a cylindrical passage in each pedicle of a vertebra, making a circumferential pedicle cut (osteotomy) through each pedicle from within the passage, separating each pedicle cut by inserting an implant into the passage which distracts the pedicle cut to expand the spinal canal, and securing each pedicle cut, allowing the vertebra to heal with the spinal canal expanded. The implant includes an outer sleeve, an inner bolt, and expandable flanges. The outer sleeve includes an upper portion and a lower portion, with the expandable flanges connected to the lower portion and housed within the upper portion. Rotation of the inner bolt causes the upper and lower portions of the outer sleeve to separate, causing the pedicle cut to widen and the expandable flanges to radially extend into and stabilize the widened pedicle cut to effectuate expansion of the spinal canal.
Owner:INNOVATIVE SURGICAL DESIGNS

Fabric Retraction Device and Method for Minimally Invasive Surgery

InactiveUS20130066158A1Barrier to reduce body fluidsSurgeryLess invasive surgerySpinal column
The present invention is directed to methods and instruments for performing tissue retraction in minimally invasive spinal surgery. Another specific application includes surgical methods performed through the percutaneously retracted tissue at any location in a patient's body. The tissue retraction is provided by an elongated sleeve formed from fabric materials, which may include the ability to stretch beyond their original length along at least one axis, for passage of instruments or implants.
Owner:RODRIGUEZ CARLOS ANDRES

Universal percutaneous endoscopic gastrostomy tube

A universal percutaneous endoscopic gastrostomy (PEG) tube that may be used with either the push or the pull insertion method. A loop extends from the tube. A void is formed in the tube at or near the proximal end of the tube. The void communicates with the internal void that acts as a conduit for material that is transported by the tube. The tube of the invention provides the option of changing technique from push method to pull method, or from pull method to push method. The device provides a mechanism at the tip or at mid catheter, thereby allowing for change over of method.
Owner:DELEGGE REBECCA

Preparation for percutaneous administration and preparation method and application thereof

The invention relates to a paeoniflorin preparation for percutaneous administration and a preparation method. The paeoniflorin preparation percutaneous administration is prepared by mixing paeoniflorin, skeleton materials, polyacrylate and a percutaneous absorption enhancer in certain proportion. The preparation for percutaneous administration has high drug-loading rate, can effectively maintain blood concentration of a medicament in a body, can significantly improve the bioavailability of the paeoniflorin, is convenient to use, improves the adaptability of a patient, and has significant effect of preventing and treating cardiovascular and cerebrovascular diseases, particularly coronary heart disease.
Owner:北大世佳科技开发有限公司

a percutaneous nephroscope

ActiveCN103070720BLower tolerance requirementsReduce work intensitySurgical needlesTrocarRenal CalixUltimate tensile strength
A percutaneous nephroscope comprises a bridge assembly, a puncture needle, a sheath assembly and a lens assembly, wherein the bridge assembly is provided with a bridge passage and a bridge base, and the sheath assembly is provided with a sheath passage and a sheath base arranged on the end of the sheath passage. In the step of puncture, the front end of the puncture needle is inserted into and extends out of the sheath passage, and the end of the puncture needle abuts against the sheath base; when the sheath base is tightly connected with the bridge base, the sheath passage communicates with the bridge passage, and the lens assembly sequentially passes through the bridge passage and the sheath passage. The percutaneous nephroscope has the following advantages: (1) the operating procedure is simplified, the time of an operation can be shortened, the requirement on the endurance of patients is decreased, and the working intensity of doctors can be decreased; (2) particularly, unnecessary expansion which can cause the pain and tissue injuries of patients is reduced; (3) because the diameter of the sheath is small, the percutaneous nephroscope can be flexibly operated in the narrow spaces of the renal pelvis and the renal calyx, the risk of tearing kidney tissues is reduced, and moreover, the surgical cut is small and can easily heal up after the operation.
Owner:中山市环能缪特斯医疗器械科技有限公司

Percutaneous drug administration cream ,ointment of letrozole and preparation method thereof

The invention relates to the cream and the ointment of Letrozole tablet percutaneous administration and the preparation method of the cream and the ointment thereof, and relates to the cream and the ointment of the percutaneous administration and the preparation method of the cream and the ointment thereof. The invention solves the problems that the prior Letrozole tablet oral preparation cannot avoid the first pass effect of liver and the bad reaction is numerous. The cream and the ointment of the percutaneous administration are characterized in that the cream and the ointment of the percutaneous administration comprise raw materials and penetrating agent with the following percentages: 0.01 to 20 percent of Letrozole tablet and 0.1 to 20 percent of percutaneous penetrating agent. The invention has the method that through vitro and a skin penetration test, the Letrozole tablet only with oral preparation is filtered out a formula with good non-steady state / steady state distribution by a skin release curve, and then the cream and the ointment of the percutaneous administration are prepared, so as to lead principal medicine to avoid the liver first pass effect of oral administration to directly reach mammary gland target tissue, and to lead the concentration of target tissue internal medicine to be improved. Compared with the prior preparation at home and at abroad, the invention technically has the advantages that the prepared external preparation can reduce the side effect of Letrozole tablet and improve the curative effect of the Letrozole tablet, thereby the invention has good promotion and application value.
Owner:INST OF PHARMACY SHANDONG PROV ACAD OF MEDICAL SCI

Activatable medical percutaneous injection filler based on laser

The invention discloses an activatable medical percutaneous injection filler based on laser, which mainly comprises crosslinked hyaluronic acid, and a special particle component with good tissue compatibility, wherein special particles are mixed into the crosslinked hyaluronic acid filler, and are 50-100 micrometers in particle size. The action time of the filler by single injection can be prolonged to be multiple times than before by the action of the laser.
Owner:PEKING UNIV

Indapamide percutaneous controlled releast plaster and its preparation method

A release-controllable percutaneous paster of indopamide for stable releasing within 24 hr is composed of substrate, layer, medicine bearing layer, and antisticking layer. Said medicine bearing layer contains indapamide, pressure sensitive adhesive, composite percutaneous absorption promoter, plasticizer, tackiness agent and antioxidant. Its preparing process is also disclosed.
Owner:SHENYANG PHARMA UNIVERSITY

Trans-dermal drug administration type Cilnidipine paster for treating hypertension and preparation method thereof

The invention provides a trans-dermal drug administration type Cilnidipine paster for treating hypertension, which is prepared by successively stacking a backing, a drug layer and an anti-adhesion layer into a whole, wherein the drug layer is prepared from Cilnidipine, a skin penetration enhancing agent and a pressure-sensitive adhesive by the weight ratio of 1:(0.08-0.23):(0.7-1.1). The Cilnidipine paster of the invention is preferentially pasted behind the neck or the parts with vena and arteries under the skin and belongs to a trans-dermal drug administration type, thereby reducing the change of the peak valley of blood concentration, avoiding the first-pass effect of livers and the degradation of gastrointestinal tract enzymes and reducing adverse reaction; and the release quantity of the drug is controlled to be slow by dissolving the drug in the pressure-sensitive adhesive, without a controlled release film structure, therefore, the structure of the Cilnidipine paster is simple, and the effects of slow and stable drug release and hypertension reduction time extension can be achieved.
Owner:蚌埠丰原涂山制药有限公司
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