Application of compound alfuzosin hydrochloride in preparing information therapy medicines, preparation method thereof and prepared novel medicine

Abstract

The invention discloses application of compound alfuzosin hydrochloride in preparing information therapy medicines, a preparation method thereof and a prepared novel medicine. The information therapy medicines are not directly contacted with the human body when being used for therapy, medicine substance components are not consumed, only medicine information is utilized for physical therapy, the effect of chemical therapy can be achieved, a therapy window is expanded by more than one thousand times, and the side effects of the chemical therapy are avoided. After the alfuzosin hydrochloride is used as the information therapy medicine, and the contents of effective components of the alfuzosin hydrochloride are not changed. The alfuzosin hydrochloride also can be used as a conventional chemical therapy preparation to be reused effectively.

Description

technical field [0001] The invention relates to the field of medicines, in particular to a novel drug of alfuzosin hydrochloride. Background technique [0002] Compound Alfuzosin hydrochloride (Alfuzosin hydrochloride), chemical name: N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro -2-furan carboxamide hydrochloride, chemical formula C 19 h 27 N 5 o 4 HCl, molecular weight 425.91. Appearance is white crystalline powder. Alfuzosin hydrochloride is a drug for relieving benign prostatic hyperplasia, which is clinically used to treat benign prostatic hyperplasia and hypertension. The pharmaceutical preparations of alfuzosin hydrochloride include tablets, capsules and the like. Known alfuzosin hydrochloride drugs are all used as chemotherapeutic drugs, which is to allow the compound alfuzosin hydrochloride molecules to enter the human body (through oral absorption into the blood), distribute to various tissues, and through the chemical reaction of...

AI Technical Summary

Problems solved by technology

In the prior art, alfuzosin hydrochloride is used as a chemotherapeutic drug, and there are defects that cannot be overcome so far. The first is the toxic and side effects on the human body, and its annoying adverse reactions include dry mouth, nausea and vomiting, diarrhea, abdominal pain , indigestion, constipation, palpitations, orthostatic hypotension, edema, dizziness, headache, impotence, allergies, etc.; second, the treatment window is small, and due to the toxic and side effects on the human body, the effective dose that can be used is very small, which limits the therapeutic effect , the maximum dose of oral administration is 5 mg once, 10 mg per day, and poisoning can occur if the maximum dose is exceeded; the third is that there is only one use of chemotherapy drugs, and the drugs will be metabolized or excreted when they enter the human body, and cannot be used for the second time.

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