Micrometer sterilized Oviductus Ranae powder, preparation method and application thereof

A wood frog oil, micron-scale technology, applied in powder delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., to achieve the effects of enhanced hydration performance, easy absorption, and reduced water activity

Inactive Publication Date: 2012-10-03
INFINITUS (CHINA) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no report on the combination of low temperature sterilization ...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] The harvested and dried frog oil was sterilized by soaking in 90% ethanol solution at a volume concentration of -8°C, and then dried naturally in a clean workshop. The sterilized and dried Rana oil is ultrafinely pulverized by ultrafine pulverization equipment in a clean workshop. The pulverization time is 4 minutes and the pulverization temperature is -10°C. The particle diameter of the pulverized Rana oil powder is about 40 microns.

[0016] Take 3 kg of the above-mentioned wood frog oil powder, add Chinese herbal medicine extract powder and mix evenly, enter the automatic tabletting system in the clean workshop for tabletting, bottle the tablet after tabletting, and complete the production process of the wood frog oil tablet.

Embodiment 2

[0018] The harvested and dried frog oil was sterilized by soaking in 60% ethanol solution at a volume concentration of 0°C, and then dried naturally in a clean workshop. The sterilized and dried Rana oil is ultrafinely pulverized by ultrafine pulverization equipment in a clean workshop. The pulverization time is 10 minutes, the pulverization temperature is -2°C, and the particle diameter of the pulverized wood frog oil powder is about 20 microns.

[0019] Get above-mentioned wood frog oil powder 5kg, enter automatic capsule filling machine filling in clean workshop, the capsule after filling is bottled, finish the making process of wood frog oil capsule.

Embodiment 3

[0021] The harvested and dried frog oil was sterilized by soaking in 80% ethanol solution at a volume concentration of 5°C, and then dried naturally in a clean workshop. The sterilized and dried Rana oil is ultrafinely pulverized by ultrafine pulverization equipment in a clean workshop, the pulverization time is 8 minutes, and the pulverization temperature is -5°C. The particle diameter of the pulverized Rana oil powder is about 50 microns.

[0022] Take 4 kg of the above-mentioned Rana oil powder, add Chinese herbal medicine extract powder and mix evenly, enter the automatic tablet compression system in the clean workshop to compress the tablets, bottle the compressed tablets, and complete the production process of the Rana oil tablets.

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Abstract

The invention discloses a micrometer sterilized Oviductus Ranae powder with particle diameter of 0.1-500 micrometer. The Oviductus Ranae powde is prepared from low-temperature sterilized Oviductus Ranae by ultra-micronizing. The invention also discloses preparation method and application of the Oviductus Ranae powder. The invention combines low-temperature sterilizing and ultra-micronizing to produce pure, preservative-free and easily-absorbable fine micrometer Oviductus Ranae powder in large scale, and the preparation method facilitates mass production of high-quality pharmaceutical, food or health food preparation.

Description

technical field [0001] The invention belongs to the technical field of Chinese herbal medicines, and in particular relates to a micron-scale sterilized wood frog oil powder and its preparation method and application. Background technique [0002] Rana Oil ( Oviductus Ranae ), also known as toad oil and frog oil, is the female Chinese Rana ( Rana temporaira chensinensis David ) of the dried fallopian tubes, is a prestigious tonic Chinese medicine. From the theory of traditional Chinese medicine, frog oil tastes sweet, salty, flat in nature, and belongs to the lung and kidney meridian. It has the functions of nourishing kidney and essence, moistening lung and nourishing yin. disease. Analysis of the nutritional components of Rana oil shows that Rana oil is rich in protein, complete in amino acids, and has high nutritional and medicinal value. [0003] Due to the high nutritional value and high water content of Rana oil, it is easy to be contaminated by microorganisms when...

Claims

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Application Information

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IPC IPC(8): A61K35/56A61K9/14A61P1/14A61K35/65
Inventor 李惠森
Owner INFINITUS (CHINA) CO LTD
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