Non-woven fabric for medical use and process for the preparation thereof

A non-woven fabric and medical technology, applied in the application field of the non-woven fabric, can solve the problems that cells cannot maintain a smooth surface, complications, blood vessel bleeding, etc.

Inactive Publication Date: 2012-10-03
无纺技术医学有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the inner region, neovascular intima repeatedly forms at junctional sites, but the cells do not maintain a smooth surface
Vessels made of ePTFE are prone to tube bleeding, which can lead to complications and prolong surgery time during surgery

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0037] In one embodiment, a tubular nonwoven having an inner surface and an outer surface can be produced by spraying onto a generally cylindrical support. In particular, the porosity of the tubular nonwoven according to the invention substantially allows the passage of liquid components of blood while substantially retaining cellular components of blood. An advantage of this is that autonomous ventilation can be created while sealing off non-gaseous components. For example, after blood begins to flow through the implanted blood vessel, the air contained therein can seep out through the stomata, while liquid and solid components can only partially or not pass through the stomata.

[0038] In particular, the inner surface structure of the tubular non-woven fabric of the present invention has a finer structure of the polycarbonate polyurethane microfiber layer compared with the outer surface structure, so that the ratio of the pore size on the lower side to the pore size on the up...

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Abstract

Process for preparing a non-woven fabric for medical use, comprising the following steps: -performing a spraying process in which -a spray jet is generated from a polycarbonate urethane plastic solution having a viscosity of from 800 to 1500 Pa.s using a spraying unit from which the polycarbonate urethane plastic solution exits; -said spray jet includes at least one strand of a single microfiber that may have a diameter of from 1 to 15 [mu]m, preferably a diameter of from 2 to 10 [mu]m; -said at least one strand of the single microfiber is sprayed onto a support, wherein -the support is moved relative to the spraying unit, or the spraying unit is moved relative to the support; -the spraying process is repeated several times to form polycarbonate urethane microfiber layers; -whereby polycarbonate urethane microfibers formed from the individual spraying processes overlay each other and adhere to each other at the respective contact points; and -a non-woven fabric having a fibrillar microporous structure is formed; -and optionally detached from the support after the last spraying process.

Description

technical field [0001] The present invention relates to a medical non-woven fabric and a method for preparing the non-woven fabric of the present invention, in particular to a non-woven fabric composed of interconnected fine fibrous fibers (such as polyurethane), and the application of the non-woven fabric . Background technique [0002] DE-A-28 06 030 describes a process for producing nonwovens from polyurethanes. In the method described above, polyurethane is dissolved in a solvent such as dimethylformamide, acetone or toluene and spun into microfibers using automated spray equipment. The formed microfibers are applied layer by layer at a fixed angle to a rotating forming part, where they bond and fuse together layer by layer at crossing sites. By the method described, nonwovens containing a microporous structure can be produced. Since the basic mechanical properties and biological properties of this material generally meet the requirements of artificial blood vessels (...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/06A61F2/24A61F2/02A61L27/18A61L31/06A61L17/00D04H3/009D04H3/16D04H1/4358D04H1/56D04H3/02D04H3/033D04H3/07
CPCD04H3/07D04H1/4358D04H3/16B29C41/08A61L27/18B29L2031/726B29K2105/122A61F2240/001D04H3/033A61F2/06D04H1/56B29K2069/00D04H3/02B29C41/085B29L2031/7534C08L75/04
Inventor 弗兰克·威廉斯克里斯托夫·克拉森斯蒂芬妮·坎普夫
Owner 无纺技术医学有限公司
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