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Microchip and method of producing microchip

A microchip and substrate technology, applied in chemical instruments and methods, fluid controllers, laboratory utensils, etc., can solve problems such as air gap generation, analysis accuracy or analysis efficiency reduction, difficulties, etc.

Active Publication Date: 2012-10-17
SONY CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In micro-TAS, it is difficult to introduce the sample solution into the well or channel due to the use of a trace amount of sample, the introduction of the sample solution may be inhibited by the retention of air in the well and the like, and it takes a long time to introduce the sample. time
In addition, air gaps may be created within wells and the like when sample solutions are introduced
Therefore, the amount of the sample solution introduced into the well changes, resulting in a decrease in the accuracy of the analysis or the efficiency of the analysis
When the sample is heated (for example, in PCR), the residual air gap in the well expands, which will inhibit the reaction or reduce the precision of the analysis

Method used

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  • Microchip and method of producing microchip
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  • Microchip and method of producing microchip

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Experimental program
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Embodiment Construction

[0044] Embodiments of the present application will be described in detail below with reference to the accompanying drawings.

[0045] 1. Microchip A according to the first embodiment

[0046] (1-1) Structure and Formation Method of Microchip A

[0047] (1-2) Introduction of sample solution to microchip A

[0048] 2. Microchip B according to the second embodiment

[0049] (2-1) Structure of microchip B

[0050] (2-2) Introduction of sample solution to microchip B

[0051] 3. Microchip C according to the third embodiment

[0052] (3-1) Structure and Formation Method of Microchip C

[0053] (3-2) Introduction of sample solution to microchip C

[0054] 1. Microchip according to the first embodiment

[0055] (1-1) The structure and formation method of the microchip A.

[0056] figure 1 A schematic diagram of the upper surface of the microchip according to the first embodiment is shown in , figure 2and image 3 A schematic cross-sectional view of it is shown. figur...

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PUM

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Abstract

A microchip is provided. The microchip (A) includes a substrate structure including a fluid channel (2) configured to contain a sample solution, wherein the fluid channel is maintained at a pressure lower than atmospheric pressure prior to injection of the sample solution into the fluid channel.

Description

technical field [0001] This application claims priority from Japanese Priority Patent Application JP2010-028241 filed with the Japan Patent Office on February 10, 2010, the entire contents of which are hereby incorporated by reference. [0002] The present application relates to microchips and methods of manufacturing microchips. More specifically, the present application relates to microchips for chemical or biological analysis of substances introduced into regions provided on a substrate of the microchip. Background technique [0003] In recent years, by applying microfabrication techniques in the semiconductor industry, microchips with wells and flow channels formed on substrates made of silicon or glass for performing chemical and biological analyzes have been developed (for example, see Patent Literature 1). In the field of practical medicine, these microchips have begun to be used, for example, as electrochemical detectors or small electrochemical sensors for liquid ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00
CPCB01L3/50273B01L2400/049B01L2300/044B01L2300/0887B01L2200/141B01L3/5027B01L2200/0689B01L2200/10B01L2300/12B01L2300/123
Inventor 渡边英俊濑川雄司
Owner SONY CORP