Time-of-flight mass spectrometer electronics reading method based on pulse front edge time measurement and amplitude correction algorithm

Abstract

The invention discloses a time-of-flight mass spectrometer electronics reading method which can improve time resolution and a quantitative performance of a time-of-flight mass spectrometer at the same time and is different from an electronics reading scheme of a traditional time-of-flight mass spectrometer by an ADC (Analog to Digital Converter) waveform sampling or a TDC (Time to Digital Converter) pulse time measuring. The pulse front edge time measurement and a pulse forming sampling scheme are combined; the front edge time measured by the TDC is corrected by amplitude information obtained by a middle and low speed ADC for sampling a formed pulse, so that a time resolution effect is obviously improved, and the quantitative performance of an apparatus is improved. According to the reading method, an expensive high-speed ADC (over 1G SPS (samples per second) ) chip is replaced by a pulse forming circuit and the middle and low-speed ADC (about 100M of SPS); a constant fraction discriminator (CFD) circuit in a traditional time-of-flight mass spectrometer reading electronics is replaced by utilizing direct pulse front edge screening, and apparatus cost is reduced when a performance is improved.

Description

technical field [0001] The invention belongs to the field of time-of-flight mass spectrometers, in particular to an electronic readout that combines pulse front time measurement and amplitude-time correction algorithm, can simultaneously improve the time resolution and quantitative performance of time-of-flight mass spectrometers, and can save costs method. Background technique [0002] As a high-end analytical instrument, time-of-flight mass spectrometer has a wide range of applications in environmental monitoring, food safety, biology, pharmaceuticals and other fields. One of the most important indicators for evaluating the performance of a time-of-flight mass spectrometer is its resolution, which is not only related to physical design and machining, but also directly depends on the time measurement accuracy of the instrument's readout electronics. [0003] Typically, the readout electronics of a time-of-flight mass spectrometer tends to employ one of two options: [000...

AI Technical Summary

Problems solved by technology

[0006] The readout electronics of the existing time-of-flight mass spectrometers are basically based on the above two methods. Although the functions can be realized to a certain extent, there are disadvantages that cannot be ignored, which limit the application fields of time-of-flight mass spectrometers, and their Independent industrialization

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