Improvements to the tight connection and tight transfer between two housings in view of an aseptic transfer therebetween

A shell and connection device technology, applied in chemical instruments and methods, gas/liquid distribution and storage, and protected small chambers, etc., can solve the problems of large volume, no partition configuration, soft nozzle pollution, etc.

Active Publication Date: 2012-12-12
SARTORIUS STEDIM ASEPTICS SA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The technique of using nozzles poses several problems: the risk of forgetting to install the nozzles or positioning them incorrectly when manufacturing the second housing, errors in use, risk of contamination when installing soft nozzles, etc.
The technique of using rigid tubes brings other problems: larger volume occupied in the first housing, risk of particles, etc.
However, none of these documents provides the configuration of the communicating space and the divider between the inner critical line of the annulus and the outer critical line of the annulus

Method used

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  • Improvements to the tight connection and tight transfer between two housings in view of an aseptic transfer therebetween
  • Improvements to the tight connection and tight transfer between two housings in view of an aseptic transfer therebetween
  • Improvements to the tight connection and tight transfer between two housings in view of an aseptic transfer therebetween

Examples

Experimental program
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Embodiment Construction

[0158] The aseptic and sealed transfer device between the first housing 1 and the second housing 2 considered here is referred to as a "double door" device. By way of example but not limitation, such devices are known brand and of the type described in patent document EP-A-0688020.

[0159] This transfer may involve as many technical fields as necessary, especially but not exclusively the field of biopharmaceuticals.

[0160] A first housing 1 (eg fixed, rigid and relatively large in size) comprises a structure comprising a first wall 3 which is closed, solid and rigid but provided with a first opening 4 which itself Delimited by a first annular flange 5 having an outer surface 5a, both the opening 4 and the flange 5 are for example circular, this embodiment being non-limitative. According to this embodiment, the first wall is vertical or inclined at an angle of about 30° to 45° with respect to the vertical. A wall 3 having an inner surface 3 b delimits the inner space 1 a...

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Abstract

The invention relates to a device for a tight connection between two housings (1, 2), a first housing (1) comprising a wall (3), an opening (4), a flange (5) and a door (6), and a second housing (2) comprising a wall (7), an opening (8), a flange (9) and a door (10). The flanges (5 and 9) are complementary, and means are used to displace the door (6). Means are used to hold said two doors (6 and 10) against each other, and the housings (1 and 2) communicate between each other via a communication space (13). There is an inner annular critical line (LCi) on the door (6) and an outer annular critical line (LCe) of risk of contamination on the flange (9). The device comprises means (25 and / or 26) that are structurally integrated into the door (6) and / or the flange (9) and can form a separation (25, 26) between the communication space (13) and the inner annular critical line (LCi) and / or the outer annular critical line (LCe), when the door (6) and the door (10) are open.

Description

technical field [0001] The invention relates to an improvement in the aseptic transfer between two housings for a sealed connection and a sealed transfer, limiting the risk of contamination at the position of the internal and external critical lines. [0002] A more specific object of the present invention is to provide a sealed connection between two housings, an aseptic transfer device comprising such a sealed connection, and a first housing and a second housing as part of such an aseptic transfer device, It also consists in the method of operation of the seal connection device and the method of operation of the seal transfer device. Background technique [0003] Aseptic transfer devices of the double door type are known. By way of example only, the Known device of the brand and patent document EP-A-0688020, which describes a sealed connection device between two housings isolated from the external medium. [0004] There is an embodiment of a structure being part of a f...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L1/02B08B15/02B25J21/02F16J13/18F16J13/20F16J13/22G21F7/005
CPCF16J13/18B01L2300/041B01L2300/043B01L2300/045G21F7/005B01L1/02F16J13/02B01L2200/141F16J13/22
Inventor S·阿莫I·盖伊M·拉贝达恩G·诺迪恩
Owner SARTORIUS STEDIM ASEPTICS SA
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