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Chinese medicinal preparation for controlling parasites of aquatic animal as well as preparation method and application thereof

An aquatic animal and extract technology is applied in the application of traditional Chinese medicine preparations, the preparation of traditional Chinese medicine solutions, and the field of traditional Chinese medicine preparations for preventing and controlling ectoparasites in aquatic animals, and can solve problems such as increasing drug dosage and high resistance to chemical insecticides. , to reduce pollution and achieve significant effect

Active Publication Date: 2014-08-06
武汉中博水产生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The object of the present invention is to provide a traditional Chinese medicine preparation for preventing and treating ectoparasites of aquatic animals, which is cost-effective and has remarkable effects. problems, avoid increasing drug dosage due to high drug resistance, and reduce environmental pollution

Method used

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  • Chinese medicinal preparation for controlling parasites of aquatic animal as well as preparation method and application thereof
  • Chinese medicinal preparation for controlling parasites of aquatic animal as well as preparation method and application thereof
  • Chinese medicinal preparation for controlling parasites of aquatic animal as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A traditional Chinese medicine preparation for preventing and treating ectoparasitic diseases of aquatic animals, the composition of which is as follows:

[0029] 5g of ethyl acetate extract of Euphorbia chamaejas, 5g of emulsifier (OP-10 or 656-A), 1g of stabilizer (propylene glycol), and dilute to 100ml with acetone.

[0030] Its preparation method is as follows:

[0031] 1) Weigh 50g of Euphorbia chamaejasma and crush it to 20 meshes, and use 80% ethanol (v / v) for Soxhlet extraction (Pharmacopoeia Committee of the People's Republic of China. Pharmacopoeia of the People's Republic of China [S]. Beijing: Chemical Industry Press , 2005.), collected the extract, recovered ethanol, and obtained about 100ml of concentrated stock solution;

[0032] 2) Extract four times with petroleum ether, 200ml each time, separate the petroleum ether layer, and keep the water phase;

[0033] 3) The aqueous phase was extracted five times with ethyl acetate, 300ml each time, the extracts...

Embodiment 2

[0039] A traditional Chinese medicine preparation for preventing and treating ectoparasitic diseases of aquatic animals, the composition of which is as follows:

[0040] Euphorbia chamaejasbae ethyl acetate extract 3g, emulsifier (656-A) 5g, stabilizer (propylene glycol) 1g, acetone to 100ml.

[0041] Its preparation method is the same as Example 1 except that the weight of raw materials is different.

Embodiment 3

[0043] A traditional Chinese medicine preparation for preventing and treating ectoparasitic diseases of aquatic animals, the composition of which is as follows:

[0044] 10g of ethyl acetate extract of Euphorbia chamaejasma, 10g of emulsifier (OP-10), 3g of stabilizer (propylene glycol), and dilute to 100ml with acetone.

[0045] Its preparation method is the same as Example 1 except that the weight of raw materials is different.

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Abstract

The invention discloses a Chinese medicinal preparation for controlling parasites of aquatic animal as well as a preparation method and application thereof. The Chinese medicinal preparation for controlling the external parasites of the aquatic animals is prepared by the following steps: (1) carrying out Soxhlet extraction on euphorbia fischeriana by using 80% ethanol and collecting an extracting solution; (2) extracting by using petroleum ether; (3) extracting by using ethyl acetate to obtain solid residues; (4) eluting the solid residues by using ethanol, and volatilizing a solvent to obtain an euphorbia fischeriana ethyl acetate extract; and (5) weighing 3-10g of the extract obtained in (4), dissolving the extract completely by using acetone, adding 5-10g of emulsifier and 1-2g of stabilizer, and fixing the volume to be 100ml by using acetone. The method can be used for separating active parasite-killing components of the euphorbia fischeriana, is feasible and is convenient to operate, the safety concentration of the euphorbia fischeriana extract to crucian and grass crap is 2.61ppm and 2.38ppm respectively, thus the Chinese medicinal preparation is relatively safe for fish, can be applied to control of the external parasites of the aquatic animals in aquaculture production and is suitable for meeting the requirements of intensified and large-scale aquaculture.

Description

technical field [0001] The invention belongs to the technical field of prevention and treatment of aquatic animal diseases (fishing medicine), more specifically relates to a traditional Chinese medicine preparation for preventing and treating ectoparasites of aquatic animals, and also relates to a preparation method of a traditional Chinese medicine solution for preventing and controlling ectoparasites of aquatic animals, and also relates to Application of a traditional Chinese medicine preparation for preventing and controlling aquatic animal parasites. Background technique [0002] Fish parasites are common and frequently-occurring diseases in aquaculture. After the fish body is infected by parasites, the light ones will lose weight and the bait coefficient will increase. In recent years, with the increase of breeding density and the deterioration of the breeding water environment, fish parasites are also showing a trend of multiple, frequent, diverse and difficult to cure...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/47A61K36/83A61P33/14
Inventor 喻运珍艾桃山高祥林余少梅张生元余姣龙李勤
Owner 武汉中博水产生物技术有限公司
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